『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=162893EID:162893, Map:0, LastModified:2018年5月23日(水) 17:08:29, Operator:[[ADMIN]], Avail:TRUE, Censor:0, Owner:[[学科長]/[徳島大学.医学部.医科栄養学科]], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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審査 (推奨): Peer Review [継承]
カテゴリ (推奨): 研究 [継承]
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学究種別 (推奨):
組織 (推奨): 1.徳島大学.大学院ヘルスバイオサイエンス研究部.生体システム栄養科学部門.医療栄養科学講座 (2004年4月1日〜) [継承]
著者 (必須): 1. (英) Ikefuji Hiroyuki (日) (読)
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2.野村 昌弘
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3.中屋 豊
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4. (英) Mori Toshifumi (日) (読)
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5. (英) Kondo Noriyasu (日) (読)
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6. (英) Leishi Kiyoshi (日) (読)
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7. (英) Fujimoto Sayuri (日) (読)
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8.伊東 進
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題名 (必須): (英) Visualization of cardiac dipole using a current density map: detection of cardiac current undetectable by electrocardiography using magnetocardiography.  (日)    [継承]
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要約 (任意): (英) A close relationship exists between electric current and the magnetic field. However, electricity and magnetism have different physical characteristics, and magnetocardiography (MCG) may provide information on cardiac current that is difficult to obtain by electrocardiography (ECG). In the present study, we investigated the issue of whether the current density map method, in which cardiac current is estimated from the magnetic gradient, facilitates the visualization of cardiac current undetectable by ECG. The subjects were 50 healthy adults (N group), 40 patients with left ventricular overloading (LVO group), 15 patients with right ventricular overloading (RVO group), 10 patients with an old inferior myocardial infarction (OMI group), and 30 patients with diabetes mellitus (DM group). MCGs were recorded with a second derivative superconducting quantum interference device (SQUID) gradiometer using liquid helium. Isopotential maps and current density maps from unipolar precordial ECG leads and MCGs, respectively, were prepared, and the cardiac electric current was examined. The current density map at the ventricular depolarization phase showed one peak of current density in the N group. However, in the OMI group, the current density map showed multiple peaks of current density areas. In the RVO group, two peaks of current densities were detected at the right superior region and left thoracic region and these two diploles appeared to be from the right and left ventricular derived cardiac currents, respectively. Moreover, there was a significant correlation between the magnitude of the current density from the right ventricle and the systolic pulmonary arterial pressure. The current density map at the ventricular repolarization phase in the N group showed only a single current source. However, abnormal current sources in the current density maps were frequently detected even in patients showing no abnormalities on isopotential maps in the LVO, DM, and OMI groups. The findings herein suggest that opposing dipoles of the ventricular depolarization and repolarization vectors were summed and evaluated as a single dipole in the electrocardiogram. However, MCG facilitated the detection of multiple dipoles because of its superior spatial resolution as well as difference in physical properties between magnetic and electrical fields. Our results suggest that MCG with a current density map is useful for detecting cardiac current undetectable by ECG in an early stage.  (日)    [継承]
キーワード (推奨): 1. (英) Adult (日) (読) [継承]
2. (英) Aged (日) (読) [継承]
3.糖尿病 (diabetes mellitus) [継承]
4. (英) Electrocardiography (日) (読) [継承]
5. (英) Female (日) (読) [継承]
6.心臓 (heart) [継承]
7. (英) Humans (日) (読) [継承]
8. (英) Magnetocardiography (日) (読) [継承]
9. (英) Male (日) (読) [継承]
10. (英) Middle Aged (日) (読) [継承]
11. (英) Myocardial Infarction (日) (読) [継承]
12. (英) Ventricular Dysfunction, Left (日) (読) [継承]
発行所 (推奨):
誌名 (必須): The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)

ISSN (任意): 1343-1420
ISSN: 1343-1420 (pISSN: 1343-1420, eISSN: 1349-6867)
Title: The journal of medical investigation : JMI
Title(ISO): J Med Invest
Supplier: 徳島大学
Publisher: Tokushima Daigaku Igakubu
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年月日 (必須): 西暦 2007年 2月 初日 (平成 19年 2月 初日) [継承]
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DOI (任意): 10.2152/jmi.54.116    (→Scopusで検索) [継承]
PMID (任意): 17380022    (→Scopusで検索) [継承]
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Scopus (任意): 2-s2.0-34247869051 [継承]
機関リポジトリ : 111502 [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Cardiology, JA Kochi Hospital, Kochi, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Hiroyuki Ikefuji, Masahiro Nomura, Yutaka Nakaya, Toshifumi Mori, Noriyasu Kondo, Kiyoshi Leishi, Sayuri Fujimoto and Susumu Ito : Visualization of cardiac dipole using a current density map: detection of cardiac current undetectable by electrocardiography using magnetocardiography., The Journal of Medical Investigation : JMI, Vol.54, No.1-2, 116-123, 2007.
欧文冊子 ● Hiroyuki Ikefuji, Masahiro Nomura, Yutaka Nakaya, Toshifumi Mori, Noriyasu Kondo, Kiyoshi Leishi, Sayuri Fujimoto and Susumu Ito : Visualization of cardiac dipole using a current density map: detection of cardiac current undetectable by electrocardiography using magnetocardiography., The Journal of Medical Investigation : JMI, Vol.54, No.1-2, 116-123, 2007.

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