『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=162861EID:162861, Map:0, LastModified:2012年10月24日(水) 14:09:03, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[六反 一仁], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨):
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組織 (推奨):
著者 (必須): 1. (英) Wada T (日) (読)
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2.勢井 宏義 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.生理系.統合生理学])
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3. (英) Kusumoto K (日) (読)
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4. (英) Kitaoka K (日) (読)
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[継承]
5. (英) Chikahisa S (日) (読)
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6.六反 一仁
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7. (英) Morita Y (日) (読)
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題名 (必須): (英) Geranylgeranylacetone, an inducer of HSP 70, attenuates REM sleep rebound after sleep deprivation.  (日)    [継承]
副題 (任意):
要約 (任意): (英) The effect of pretreatment of geranylgeranylacetone (GGA), an inducer of heat shock protein (HSP) 70, on responses in sleep and core body temperature (Tcore) against sleep deprivation (SD) was examined in rats. After 3 days of GGA or vehicle injection, a 6-h period of SD was performed. During the recovery period, both rapid-eye movement (REM) and non-REM (NREM) sleep were increased in both GGA- and vehicle-injected rats. However, in GGA-injected rats, REM-sleep rebound was significantly suppressed, while NREM-sleep rebound remained unaffected. In addition, the increase of Tcore caused by SD was also attenuated in GGA-injected rats. In the hippocampus, both SD and the GGA pretreatment induced an increase in the expression of HSP70 mRNA, indicating that the SD functions as a stress for hippocampal neurons and that the GGA induces HSP70 expression. The findings suggest that pretreatment with GGA suppresses REM sleep rebound and the response of Tcore against SD.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Diterpenes (日) (読) [継承]
3. (英) HSP70 Heat-Shock Proteins (日) (読) [継承]
4. (英) Male (日) (読) [継承]
5. (英) RNA, Messenger (日) (読) [継承]
6. (英) Rats (日) (読) [継承]
7. (英) Rats, Wistar (日) (読) [継承]
8. (英) Sleep Deprivation (日) (読) [継承]
9. (英) Sleep, REM (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Brain Research Bulletin ([Elsevier])
(pISSN: 0361-9230, eISSN: 1873-2747)

ISSN (任意): 0361-9230
ISSN: 0361-9230 (pISSN: 0361-9230, eISSN: 1873-2747)
Title: Brain research bulletin
Title(ISO): Brain Res. Bull.
Publisher: Elsevier BV
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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年月日 (必須): 西暦 2006年 3月 3日 (平成 18年 3月 3日) [継承]
URL (任意):
DOI (任意): 10.1016/j.brainresbull.2006.02.004    (→Scopusで検索) [継承]
PMID (任意): 16624670    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Integrative Physiology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● T Wada, Hiroyoshi Sei, K Kusumoto, K Kitaoka, S Chikahisa, Kazuhito Rokutan and Y Morita : Geranylgeranylacetone, an inducer of HSP 70, attenuates REM sleep rebound after sleep deprivation., Brain Research Bulletin, Vol.69, No.4, 388-392, 2006.
欧文冊子 ● T Wada, Hiroyoshi Sei, K Kusumoto, K Kitaoka, S Chikahisa, Kazuhito Rokutan and Y Morita : Geranylgeranylacetone, an inducer of HSP 70, attenuates REM sleep rebound after sleep deprivation., Brain Research Bulletin, Vol.69, No.4, 388-392, 2006.

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