| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○審査 (推奨): |
| ○カテゴリ (推奨): |
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| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Oarada Motoko (日) (読)
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| 2. | (英) Gonoi Tohru (日) (読)
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| 3. | (英) Tsuzuki Tsuyoshi (日) (読)
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| 4. | (英) Igarashi Miki (日) (読)
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| 5. | 平坂 勝也
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| 6. | (英) Nikawa Takeshi (日) (読)
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| 7. | (英) Onishi Yuko (日) (読)
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| 8. | (英) Toyotome Takahito (日) (読)
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| 9. | (英) Kamei Katsuhiko (日) (読)
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| 10. | (英) Miyazawa Teruo (日) (読)
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| 11. | (英) Nakagawa Kiyotaka (日) (読)
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| 12. | (英) Kashima Minoru (日) (読)
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| 13. | (英) Kurita Nobuyuki (日) (読)
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| ○題名 (必須): | □ | (英) Effect of dietary oils on lymphocyte immunological activity in psychologically stressed mice (日)
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| ○要約 (任意): | □ | (英) Psychological stress has been shown to modulate immune functions. In this study, we investigated the effect of dietary oils (olive oil, soybean oil, and fish oil) on the social isolation stress-induced modulation of lymphocyte immunological activities in mice. In olive oil-fed, but not soybean oil- or fish oil-fed, mice, a 2-week isolation stress decreased the lymphocyte proliferative response, reduced the interferon-gamma and interleukin (IL)-10 secretions and increased the IL-4 secretion by lymphocytes. The isolation stress reduced the arachidonic acid content of lymphocytes markedly, moderately, and not at all in the olive oil-, soybean oil-, and fish oil-fed mice, respectively. In the olive oil-fed, but not soybean oil- or fish oil-fed, mice, the isolation stress up-regulated the expression level of mRNA for splenic heat-shock protein 70 and increased lymphocyte sensitivity to the antiproliferative effect of corticosterone. This is the first demonstration that effect of psychological stress on lymphocyte immunological activities can vary depending upon the dietary fatty acid composition. (日)
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| ○キーワード (推奨): | 1. | (英) Animals (日) (読)
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| 2. | (英) Appetitive Behavior (日) (読)
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| 3. | (英) Body Weight (日) (読)
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| 4. | (英) Cell Proliferation (日) (読)
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| 5. | (英) Cells, Cultured (日) (読)
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| 6. | (英) Corticosterone (日) (読)
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| 7. | 細胞質分裂 (cytokinesis)
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| 8. | (英) Dietary Fats, Unsaturated (日) (読)
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| 9. | (英) Female (日) (読)
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| 10. | 遺伝子発現 (gene expression)
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| 11. | (英) Lymphocytes (日) (読)
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| 12. | (英) Mice (日) (読)
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| 13. | (英) Mice, Inbred BALB C (日) (読)
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| 14. | (英) Organ Size (日) (読)
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| 15. | (英) RNA, Messenger (日) (読)
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| 16. | (英) Spleen (日) (読)
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| 17. | (英) Stress, Physiological (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Bioscience, Biotechnology, and Biochemistry ([社団法人 日本農芸化学会])
(pISSN: 0916-8451, eISSN: 1347-6947)
| ○ISSN (任意): | □ | 0916-8451
ISSN: 0916-8451
(pISSN: 0916-8451, eISSN: 1347-6947) Title: Bioscience, biotechnology, and biochemistryTitle(ISO): Biosci Biotechnol BiochemSupplier: 社団法人日本農芸化学会Publisher: Oxford University Press (NLM Catalog)
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(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 71
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| ○号 (必須): | □ | 1
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| ○頁 (必須): | □ | 174 182
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2007年 1月 7日 (平成 19年 1月 7日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1271/bbb.60425 (→Scopusで検索)
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| ○PMID (任意): | □ | 17213666 (→Scopusで検索)
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| ○CRID (任意): |
| ○WOS (任意): | □ | 000243915600023
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| ○Scopus (任意): | □ | 2-s2.0-33846557992
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| ○指導教員 (推奨): |
| ○備考 (任意): | 1. | (英) Article.Affiliation: Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Japan. motoko.o@faculty.chiba-u.jp (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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