| ○種別 (必須): | □ | 学術論文 (審査論文)
| [継承] |
| ○言語 (必須): | □ | 英語
| [継承] |
| ○招待 (推奨): |
| ○審査 (推奨): | □ | Peer Review
| [継承] |
| ○カテゴリ (推奨): |
| ○共著種別 (推奨): |
| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Hu Ying (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 2. | 馬 寧
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 3. | (英) Yang Miao (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 4. | (英) Semba Reiji (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| ○題名 (必須): | □ | (英) Expression and Distribution of Heme Oxygenase-2 mRNA and Protein in Rat Kidney (日)
| [継承] |
| ○副題 (任意): |
| ○要約 (任意): | □ | (英) Recent studies suggest that carbon monoxide (CO), which is formed by the enzyme heme oxygenase (HO) during the conversion of heme to biliverdin, shares some of the chemical and biological properties of nitric oxide (NO) and may play roles similar to those of NO. Heme oxygenase activity in the kidney has been reported for many years, and there are some reports on the expression of mRNA for two HO isozymes (HO-1 and HO-2) and cellular localization of HO-1 protein. However, cellular localization of HO-2 protein in the kidney under normal conditions has not been reported. In the present study we examined the expression and distribution of HO-2 mRNA and HO-2 protein in rat kidney using RNA protection assay and light and electron immunocytochemistry. RNA protection assay confirmed constitutive expression of HO-2 transcript in rat kidney. HO-2 immunoreactivity was selectively found in epithelial cells of the thick ascending limb and distal convoluted tubule, connecting tubule cells, and principal cells of the collecting duct. These results suggest that HO-2 is synthesized in the kidney and that HO-2 in the epithelial cells of renal tubules may serve as a source for CO generation under normal conditions. (日)
| [継承] |
| ○キーワード (推奨): | 1. | (英) Animals (日) (読)
| [継承] |
| 2. | (英) Blotting, Western (日) (読)
| [継承] |
| 3. | (英) Epithelial Cells (日) (読)
| [継承] |
| 4. | 遺伝子発現 (gene expression)
| [継承] |
| 5. | (英) Heme Oxygenase (Decyclizing) (日) (読)
| [継承] |
| 6. | 免疫組織化学 (immunohistochemistry)
| [継承] |
| 7. | (英) Isoenzymes (日) (読)
| [継承] |
| 8. | (英) Kidney (日) (読)
| [継承] |
| 9. | (英) Kidney Tubules (日) (読)
| [継承] |
| 10. | (英) Kidney Tubules, Distal (日) (読)
| [継承] |
| 11. | (英) Microscopy, Immunoelectron (日) (読)
| [継承] |
| 12. | (英) RNA, Messenger (日) (読)
| [継承] |
| 13. | (英) Rats (日) (読)
| [継承] |
| 14. | (英) Rats, Wistar (日) (読)
| [継承] |
| ○発行所 (推奨): |
| ○誌名 (必須): | □ | The Journal of Histochemistry and Cytochemistry (The Histochemical Society)
(pISSN: 0022-1554, eISSN: 1551-5044)
| ○ISSN (任意): | □ | 0022-1554
ISSN: 0022-1554
(pISSN: 0022-1554, eISSN: 1551-5044) Title: The journal of histochemistry and cytochemistry : official journal of the Histochemistry SocietyTitle(ISO): J Histochem CytochemPublisher: Histochemical Society (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
| [継承] |
| ○巻 (必須): | □ | 46
| [継承] |
| ○号 (必須): | □ | 2
| [継承] |
| ○頁 (必須): | □ | 249 256
| [継承] |
| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 1998年 2月 初日 (平成 10年 2月 初日)
| [継承] |
| ○URL (任意): |
| ○DOI (任意): | □ | 10.1177/002215549804600214 (→Scopusで検索)
| [継承] |
| ○PMID (任意): | □ | 9446832 (→Scopusで検索)
| [継承] |
| ○CRID (任意): |
| ○WOS (任意): |
| ○Scopus (任意): |
| ○評価値 (任意): |
| ○被引用数 (任意): |
| ○指導教員 (推奨): |
| ○備考 (任意): | 1. | (英) Article.Affiliation: Department of Anatomy, Mie University School of Medicine, Mie, Japan. (日)
| [継承] |
| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
| [継承] |