『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=160591EID:160591, Map:0, LastModified:2017年12月4日(月) 14:07:55, Operator:[[ADMIN]], Avail:TRUE, Censor:0, Owner:[佐藤 陽一], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Nakano Takuro (日) (読)
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2.新家 利一
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3.勢井 雅子
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4.佐藤 陽一 ([徳島大学.大学院医歯薬学研究部.薬学域.薬科学部門.生命薬学系.医薬品情報学])
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5.梅野 真由美
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6. (英) Sakamoto Kozue (日) (読)
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7.野村 以徂子
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8.中堀 豊
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題名 (必須): (英) A/G heterozygote of the A-3826G polymorphism in the UCP-1 gene has higher BMI than A/A and G/G homozygote in young Japanese males  (日)    [継承]
副題 (任意):
要約 (任意): (英) UCP-1 is suggested to have important roles for thermogenesis and energy expenditure. To elucidate whether the A-3826G polymorphism that is located in the 5' flanking region of the UCP-1 gene has roles in healthy young people, the polymorphism was genotyped among 251 young Japanese men whose mean age is 22.7 years old. We analyzed relationship between the A-3826G polymorphism and body mass index (BMI) or six biochemical parameters, serum concentration of total cholesterol (TC), high density lipoprotein (HDL) cholesterol, triglyceride (TG), asparatate aminotransferase (AST), alanine aminotransferase (ALT), fasting plasma glucose. The genotype frequencies were observed at the frequencies of 24.3% for AA, 48.2% for AG and 27.5% for GG, respectively. When BMI and the biochemical parameters were compared by ANOVA among individuals with each genotype, the statistical difference was observed only for BMI (P=0.016). Bonferroni's test demonstrated that the men with the AG genotype have higher BMI than those with the AA genotype (22.4+/-2.8 vs. 21.4+/-2.2) (P=0.04). The individuals with the AG genotype also showed trend to have higher BMI than those with the GG, although the difference was not statistically apparent (22.4+/-2.8 vs. 21.5+/-2.3) (P=0.07). Our results indicated that the young healthy Japanese men with the AG heterozygote showed higher BMI than those with other genotypes.  (日)    [継承]
キーワード (推奨): 1. (英) Adenine (日) (読) [継承]
2. (英) Adult (日) (読) [継承]
3. (英) Alleles (日) (読) [継承]
4. (英) Asian Continental Ancestry Group (日) (読) [継承]
5. (英) Body Composition (日) (読) [継承]
6. (英) Body Mass Index (日) (読) [継承]
7. (英) DNA (日) (読) [継承]
8. (英) Genotype (日) (読) [継承]
9. (英) Guanine (日) (読) [継承]
10. (英) Heterozygote (日) (読) [継承]
11. (英) Homozygote (日) (読) [継承]
12. (英) Humans (日) (読) [継承]
13. (英) Ion Channels (日) (読) [継承]
14. (英) Japan (日) (読) [継承]
15. (英) Male (日) (読) [継承]
16. (英) Mitochondrial Proteins (日) (読) [継承]
17. (英) Obesity (日) (読) [継承]
18. (英) Polymorphism, Genetic (日) (読) [継承]
発行所 (推奨):
誌名 (必須): The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)

ISSN (任意): 1343-1420
ISSN: 1343-1420 (pISSN: 1343-1420, eISSN: 1349-6867)
Title: The journal of medical investigation : JMI
Title(ISO): J Med Invest
Supplier: 徳島大学
Publisher: Tokushima Daigaku Igakubu
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 53 [継承]
(必須): 3,4 [継承]
(必須): 218 222 [継承]
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年月日 (必須): 西暦 2006年 8月 初日 (平成 18年 8月 初日) [継承]
URL (任意):
DOI (任意): 10.2152/jmi.53.218    (→Scopusで検索) [継承]
PMID (任意): 16953057    (→Scopusで検索) [継承]
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機関リポジトリ : 110811 [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Human Genetics and Public Health, Institute of Health Biosciences, The University of Tokushima Graduate School.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Comparative Study  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
4.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Takuro Nakano, Toshikatsu Shinka, Masako Sei, Youichi Sato, Mayumi Umeno, Kozue Sakamoto, Isoko Nomura and Yutaka Nakahori : A/G heterozygote of the A-3826G polymorphism in the UCP-1 gene has higher BMI than A/A and G/G homozygote in young Japanese males, The Journal of Medical Investigation : JMI, Vol.53, No.3,4, 218-222, 2006.
欧文冊子 ● Takuro Nakano, Toshikatsu Shinka, Masako Sei, Youichi Sato, Mayumi Umeno, Kozue Sakamoto, Isoko Nomura and Yutaka Nakahori : A/G heterozygote of the A-3826G polymorphism in the UCP-1 gene has higher BMI than A/A and G/G homozygote in young Japanese males, The Journal of Medical Investigation : JMI, Vol.53, No.3,4, 218-222, 2006.

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