| ○種別 (必須): | □ | 学術論文 (審査論文)
| [継承] |
| ○言語 (必須): | □ | 英語
| [継承] |
| ○招待 (推奨): |
| ○審査 (推奨): | □ | Peer Review
| [継承] |
| ○カテゴリ (推奨): | □ | 研究
| [継承] |
| ○共著種別 (推奨): |
| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Nakashima Akio (日) (読) なかしま あきお
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 2. | 長谷川 敬展 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.基礎歯学系.口腔分子生理学])
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 3. | (英) Mori Saori (日) (読) もり さおり
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 4. | (英) Ueno Masaru (日) 上野 勝 (読) うえの まさる
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 5. | (英) Tanaka Shigeyasu (日) 田中 滋康 (読) たなか しげやす
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 6. | (英) Ushimaru Takashi (日) 丑丸 敬 (読) うしまる たかし
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 7. | (英) Sato Shusei (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 8. | (英) Uritani Masahiro (日) 瓜谷 真裕 (読) うりたに まさひろ
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| ○題名 (必須): | □ | (英) A starvation-specific serine protease gene, isp6+, is involved in both autophagy and sexual development in Schizosaccharomyces pombe. (日)
| [継承] |
| ○副題 (任意): |
| ○要約 (任意): | □ | (英) Schizosaccharomyces pombe isp6(+) gene encodes a vacuolar serine protease, which is specifically induced during nitrogen starvation. An isp6-disruption mutant, isp6Delta, grew normally under normal conditions but was defective in large-scale protein degradation during nitrogen starvation, a hallmark of autophagy. Vacuoles are the organelles for such drastic protein degradation but those of isp6Delta were apparently aberrant. isp6Delta was infertile under nitrogen source-free conditions with poor expression of ste11(+), a gene critical for sexual development. A protein kinase A-disruption mutant, pka1Delta, is prone to sexual development because expression of ste11(+) is derepressed. However, isp6Deltapka1Delta still showed defects in ste11(+) expression and sexual development under nitrogen source-free conditions. isp6Delta and isp6Deltapka1Delta were able to initiate sexual development to produce spores when only a small amount of a nitrogen source was present. Pat1 protein kinase negatively controls meiosis, and a temperature-sensitive mutant of pat1, pat1-114, initiates meiosis irrespective of ploidy at the restrictive temperature. However, isp6Deltapat1-114 did not start meiosis under nitrogen source-free conditions even at the restrictive temperature. These observations suggest that isp6(+) contributes to sexual development by providing a nitrogen source through autophagy. (日)
| [継承] |
| ○キーワード (推奨): | 1. | (英) Autophagy (日) (読)
| [継承] |
| 2. | (英) Epistasis, Genetic (日) (読)
| [継承] |
| 3. | (英) Gene Expression Regulation, Fungal (日) (読)
| [継承] |
| 4. | (英) Meiosis (日) (読)
| [継承] |
| 5. | (英) Membrane Proteins (日) (読)
| [継承] |
| 6. | (英) Nitrogen (日) (読)
| [継承] |
| 7. | (英) Schizosaccharomyces (日) (読)
| [継承] |
| 8. | (英) Schizosaccharomyces pombe Proteins (日) (読)
| [継承] |
| 9. | (英) Serine Endopeptidases (日) (読)
| [継承] |
| 10. | (英) Signal Transduction (日) (読)
| [継承] |
| 11. | (英) Transcription Factors (日) (読)
| [継承] |
| ○発行所 (推奨): | □ | (英) Springer International (日) (読)
| [継承] |
| ○誌名 (必須): | □ | Current Genetics ([Springer-Verlag])
(pISSN: 0172-8083, eISSN: 1432-0983)
| ○ISSN (任意): | □ | 0172-8083
ISSN: 0172-8083
(pISSN: 0172-8083, eISSN: 1432-0983) Title: Current geneticsTitle(ISO): Curr GenetSupplier: Springer Online Journal ArchivePublisher: Springer (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
| [継承] |
| ○巻 (必須): | □ | 49
| [継承] |
| ○号 (必須): | □ | 6
| [継承] |
| ○頁 (必須): | □ | 403 413
| [継承] |
| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2006年 6月 初日 (平成 18年 6月 初日)
| [継承] |
| ○URL (任意): |
| ○DOI (任意): | □ | 10.1007/s00294-006-0067-0 (→Scopusで検索)
| [継承] |
| ○PMID (任意): | □ | 16550352 (→Scopusで検索)
| [継承] |
| ○CRID (任意): |
| ○WOS (任意): |
| ○Scopus (任意): |
| ○評価値 (任意): |
| ○被引用数 (任意): |
| ○指導教員 (推奨): |
| ○備考 (任意): | 1. | (英) Article.Affiliation: Department of Chemistry, Faculty of Science, Shizuoka University, 836 Oya, 422-8539, Shizuoka, Japan. (日)
| [継承] |
| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
| [継承] |
| 3. | (英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't (日)
| [継承] |