| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○カテゴリ (推奨): |
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| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Ueda Chizuru (日) (読)
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| 2. | 高岡 司
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| 3. | (英) Sarukura Nobuko (日) (読)
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| 4. | (英) Matsuda Kazunori (日) (読)
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| 5. | 北村 嘉章 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.耳鼻咽喉科学]/[徳島大学.病院.診療科.感覚·皮膚·運動機能科.耳鼻咽喉科・頭頸部外科])
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| 6. | (英) Toda Naoki (日) (読)
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| 7. | (英) Tanaka Takeshi (日) (読)
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| 8. | 山本 茂
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| 9. | 武田 憲昭
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| ○題名 (必須): | □ | (英) Zinc nutrition in healthy subjects and patients with taste impairment from the view point of zinc ingestion, serum zinc concentration and angiotensin converting enzyme activity. (日)
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| ○要約 (任意): | □ | (英) To estimate the zinc nutrition in healthy subjects and patients with taste impairment. Dietary zinc intake, zinc concentration in the serum and the ratio of apo/holo-activities of angiotensin converting enzyme (ACE), a zinc dependent enzyme in the serum (ACE ratio) were used as indices. Healthy paramedical volunteers from a local hospital and patients with taste impairment seen in the Department of Otolaryngology, Tokushima University Hospital. Dietary zinc intake was estimated with the food frequency questionnaire (FFQ). Zinc concentration in the serum was measured by means of atomic absorption spectrometry. The ACE activity in the serum was measured spectrophotometrically as the activity of holo-ACE, which contains zinc and shows full ACE activity. The activity of apo-ACE, which dose not contain zinc, was determined as the increase of its activity over that of the initial holo-ACE activity after the addition of zinc to the serum in vitro. ACE ratio was used as a more sensitive indicator of zinc nutrition than measuring zinc concentration in the serum. There were no differences in dietary intake of zinc after adjusting for energy and zinc concentration in the serum between patients and age-adjusted healthy subjects. The ACE ratio in patients with taste impairment was significantly higher than that in age-adjusted healthy subjects (P<0.05). Our date demonstrate that zinc deficiency is a predominant factor underlying taste impairment and we hypothesize that patients with taste impairment may have malabsorption of dietary zinc. (日)
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| ○キーワード (推奨): | 1. | (英) Adult (日) (読)
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| 2. | (英) Aged (日) (読)
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| 3. | (英) Case-Control Studies (日) (読)
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| 4. | (英) Colorimetry (日) (読)
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| 5. | (英) Diet (日) (読)
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| 6. | (英) Female (日) (読)
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| 7. | (英) Humans (日) (読)
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| 8. | (英) Male (日) (読)
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| 9. | (英) Middle Aged (日) (読)
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| 10. | (英) Multivariate Analysis (日) (読)
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| 11. | (英) Peptidyl-Dipeptidase A (日) (読)
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| 12. | (英) Questionnaires (日) (読)
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| 13. | (英) Spectrophotometry, Atomic (日) (読)
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| 14. | (英) Taste Disorders (日) (読)
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| 15. | (英) Zinc (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Auris, Nasus, Larynx (Society for Promotion of International Otorhinolaryngology)
(pISSN: 0385-8146, eISSN: 1879-1476)
| ○ISSN (任意): | □ | 0385-8146
ISSN: 0385-8146
(pISSN: 0385-8146, eISSN: 1879-1476) Title: Auris, nasus, larynxTitle(ISO): Auris Nasus LarynxPublisher: Elsevier Ireland Ltd (NLM Catalog)
(医中誌Web)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 33
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| ○号 (必須): | □ | 3
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| ○頁 (必須): | □ | 283 288
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2006年 3月 10日 (平成 18年 3月 10日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1016/j.anl.2006.01.006 (→Scopusで検索)
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| ○PMID (任意): | □ | 16530365 (→Scopusで検索)
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| ○備考 (任意): | 1. | (英) Article.Affiliation: Department of International Public Health Nutrition, Institute of Health Bioscience University of Tokushima Graduate School, 3-18-15 Kuramoto, Tokushima 770-8503, Japan. (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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| 3. | (英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't (日)
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