『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=154915EID:154915, Map:0, LastModified:2012年10月29日(月) 21:11:53, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[木戸 博], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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カテゴリ (推奨):
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組織 (推奨): 1.徳島大学.分子酵素学研究センター (〜2007年3月31日/->組織[徳島大学.疾患酵素学研究センター]) [継承]
著者 (必須): 1.矢野 仁康
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2. (英) Kanesaki Y. (日) (読)
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3. (英) Koumoto Y. (日) (読)
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4. (英) Inoue M. (日) (読)
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5.木戸 博 ([徳島大学.先端酵素学研究所.重点研究部門])
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学籍番号 (推奨):
[継承]
題名 (必須): (英) Chaperone Activities of the 26S and 20S Proteasome  (日)    [継承]
副題 (任意):
要約 (任意): (英) The accumulation of misfolded or damaged proteins causes the failure of normal cell structure and functions necessary for growth and viability. To abort this adverse development, defective proteins must be rapidly repaired by molecular chaperones or destroyed by energy-dependent cytoplasmic proteases. A balance among these processes ultimately maintains cellular homeostasis. In eukaryotes, the 26S proteasome, a protease/chaperone complex, is a central component in the protein triage decision process. The 26S proteasome generally acts as a ubiquitination system, though it also selectively degrades structurally abnormal proteins in an ubiquitin-independent manner. In either case, all substrate proteins must undergo structural changes and stabilization necessary for their rapid degradation. It has, therefore, often been suggested that several chaperone functions are closely related to the stimulation of proteasomal degradation. This review summarizes recent discoveries pertaining to chaperone activities in the proteasomal degradation pathway, and to their regulation of protein breakdown mediated by the proteasome.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Humans (日) (読) [継承]
3. (英) Molecular Chaperones (日) (読) [継承]
4. (英) Proteasome Endopeptidase Complex (日) (読) [継承]
5. (英) Proteins (日) (読) [継承]
6. (英) Ubiquitin (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Current Protein & Peptide Science (Bentham Science Publishers)
(pISSN: 1389-2037, eISSN: 1875-5550)

ISSN (任意): 1389-2037
ISSN: 1389-2037 (pISSN: 1389-2037, eISSN: 1875-5550)
Title: Current protein & peptide science
Title(ISO): Curr Protein Pept Sci
Publisher: Bentham Science Publishers
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 197 203 [継承]
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年月日 (必須): 西暦 2005年 4月 3日 (平成 17年 4月 3日) [継承]
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DOI (任意): 10.2174/1389203053545453    (→Scopusで検索) [継承]
PMID (任意): 15853655    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) Article.Affiliation: Division of Enzyme Chemistry, Institute for Enzyme Research, The University of Tokushima, Tokushima 770-8503, Japan. yano@ier.tokushima-u.ac.jp  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Review  (日)    [継承]
4.(英) NumberOfReferences: 68  (日)    [継承]

標準的な表示

和文冊子 ● Mihiro Yano, Y. Kanesaki, Y. Koumoto, M. Inoue and Hiroshi Kido : Chaperone Activities of the 26S and 20S Proteasome, Current Protein & Peptide Science, Vol.6, No.2, 197-203, 2005.
欧文冊子 ● Mihiro Yano, Y. Kanesaki, Y. Koumoto, M. Inoue and Hiroshi Kido : Chaperone Activities of the 26S and 20S Proteasome, Current Protein & Peptide Science, Vol.6, No.2, 197-203, 2005.

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