『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.徳島大学.分子酵素学研究センター (〜2007年3月31日/->組織[徳島大学.疾患酵素学研究センター]) [継承]
著者 (必須): 1.木戸 博 ([徳島大学.先端酵素学研究所.重点研究部門])
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[継承]
2. (英) Izumi K. (日) (読)
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[継承]
3. (英) Otsuka H. (日) (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
4. (英) Fukusen N. (日) (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
5. (英) Kato Y. (日) (読)
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学籍番号 (推奨):
[継承]
6. (英) Katunuma N. (日) (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) A Chymotrypsin-type Serine Protease in Rat Basophilic Leukemia Cells: Evidence for its Immunological Identity with Atypical Mast Cell Protease  (日)    [継承]
副題 (任意):
要約 (任意): (英) Activity of a chymotrypsin-type serine protease was found in a subline of rat basophilic leukemia (RBL-2H3) cells. The protease was immunologically cross-reactive with anti-atypical mast cell protease immunoglobulin (Ig) G, and its activity was inhibited in a dose-dependent manner by the antibody. The apparent m.w. of the protease that reacted with the antibody was 25,000, which was identical with that of atypical mast cell protease in rat mucosal mast cells. These results show that the chymotrypsin type serine protease in RBL-2H3 cells is immunologically identical with atypical mast cell protease, which was first purified from rat small intestine. Immunohistochemical studies showed that the protease was located not only in intracytoplasmic granules but also in organelles synthesizing protein, such as cisternae of the rough endoplasmic reticulum, perinuclear spaces, and the Golgi apparatus. However, no immunoreactivity was demonstrated in rat basophils. The activity of the protease increased in the exponential phase of growth of RBL-2H3 cells in which some activity was also detected in the medium, and it decreased in the late stationary phase.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Basophils (日) (読) [継承]
3. (英) Cell Line (日) (読) [継承]
4. (英) Chymases (日) (読) [継承]
5. (英) Chymotrypsin (日) (読) [継承]
6. (英) Cross Reactions (日) (読) [継承]
7. (英) Endopeptidases (日) (読) [継承]
8. (英) Histocytochemistry (日) (読) [継承]
9. (英) Immunoglobulin G (日) (読) [継承]
10. (英) Leukemia (日) (読) [継承]
11. (英) Male (日) (読) [継承]
12. (英) Mast Cells (日) (読) [継承]
13. (英) Rats (日) (読) [継承]
14. (英) Rats, Inbred Strains (日) (読) [継承]
15. (英) Serine Endopeptidases (日) (読) [継承]
16. (英) Staining and Labeling (日) (読) [継承]
発行所 (推奨):
誌名 (必須): The Journal of Immunology ([The American Association of Immunologists])
(pISSN: 0022-1767, eISSN: 1550-6606)

ISSN (任意): 0022-1767
ISSN: 0022-1767 (pISSN: 0022-1767, eISSN: 1550-6606)
Title: Journal of immunology (Baltimore, Md. : 1950)
Title(ISO): J Immunol
Publisher: American Association of Immunologists
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 136 [継承]
(必須): 3 [継承]
(必須): 1061 1065 [継承]
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年月日 (必須): 西暦 1986年 4月 1日 (昭和 61年 4月 1日) [継承]
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PMID (任意): 2416825    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Hiroshi Kido, K. Izumi, H. Otsuka, N. Fukusen, Y. Kato and N. Katunuma : A Chymotrypsin-type Serine Protease in Rat Basophilic Leukemia Cells: Evidence for its Immunological Identity with Atypical Mast Cell Protease, The Journal of Immunology, Vol.136, No.3, 1061-1065, 1986.
欧文冊子 ● Hiroshi Kido, K. Izumi, H. Otsuka, N. Fukusen, Y. Kato and N. Katunuma : A Chymotrypsin-type Serine Protease in Rat Basophilic Leukemia Cells: Evidence for its Immunological Identity with Atypical Mast Cell Protease, The Journal of Immunology, Vol.136, No.3, 1061-1065, 1986.

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