『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Sasagawa Takayo (日) (読)
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[継承]
2. (英) Oka Tatsuzo (日) (読)
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3.德村 彰
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4. (英) Nishimoto Yuriko (日) (読)
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5. (英) Munoz Saturnino (日) (読)
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6. (英) Kuwahata Masashi (日) (読)
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7. (英) Okita Misako (日) (読)
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8. (英) Tsuji Hideaki (日) (読)
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9. (英) Natori Yasuo (日) (読)
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題名 (必須): (英) Analysis of the fatty acid components in a perchloric acid-soluble protein  (日)    [継承]
副題 (任意):
要約 (任意): (英) We had previously found that a perchloric acid-soluble protein (PSP1) occurs in rat liver, and that this novel protein inhibits protein synthesis in a rabbit reticulocyte lysate system (T. Oka, H. Tsuji, C. Noda, K. Sakai, Y.-H. Hong, I. Suzuki, S. Muñoz, Y. Natori, J. Biol. Chem. 270 (1995) 30060-30067). In the present study, we analyzed lipid components bound to PSP1. Native PSP1 was purified from rat liver using Sephadex G-75, DE-52 cellulose and IgGPSP-affinity chromatography, and the lipid components were extracted. The components obtained from the purified PSP1 were shown to be free fatty acids by thin-layer chromatography. By GC-MS, six major fatty acids were identified as 14:0, 16:0, 18:0, 18:1, 18:2 and 20:4. 1 mol of PSP1 contained 1.26 mol of total fatty acid components. The fatty acid-binding assay of PSP1 showed that the Bmax was 1.25 mol fatty acid/mol PSP1 and the Kd value for palmitic acid was 6.03 microM. The concentration of PSP1 mRNA in rat liver increased 2.3-fold by the administration of peroxisome proliferator, bezafibrate. These findings show that PSP1 is a fatty acid-binding protein-like protein, which is involved in the intracellular metabolism of fatty acid and is quite different from the known fatty acid-binding proteins.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Carrier Proteins (日) (読) [継承]
3. (英) Fatty Acid-Binding Proteins (日) (読) [継承]
4. (英) Fatty Acids (日) (読) [継承]
5. (英) Heat-Shock Proteins (日) (読) [継承]
6. (英) Liver (日) (読) [継承]
7. (英) Male (日) (読) [継承]
8. (英) Myelin P2 Protein (日) (読) [継承]
9.心筋 (myocardium) [継承]
10. (英) Neoplasm Proteins (日) (読) [継承]
11. (英) Nerve Tissue Proteins (日) (読) [継承]
12. (英) Protein Synthesis Inhibitors (日) (読) [継承]
13. (英) RNA, Messenger (日) (読) [継承]
14. (英) Rats (日) (読) [継承]
15. (英) Rats, Wistar (日) (読) [継承]
16. (英) Recombinant Proteins (日) (読) [継承]
17. (英) Ribonucleases (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids ([Elsevier Science])
(pISSN: 1388-1981, eISSN: 1879-2618)

ISSN (任意): 1388-1981
ISSN: 1388-1981 (pISSN: 1388-1981, eISSN: 1879-2618)
Title: Biochimica et biophysica acta. Molecular and cell biology of lipids
Title(ISO): Biochim Biophys Acta Mol Cell Biol Lipids
Publisher: Elsevier B.V.
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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年月日 (必須): 西暦 1999年 3月 25日 (平成 11年 3月 25日) [継承]
URL (任意): http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VNN-3W4GK5W-5&_coverDate=03%2F25%2F1999&_alid=436025813&_rdoc=1&_fmt=&_orig=search&_qd=1&_cdi=6183&_sort=d&view=c&_acct=C000008258&_version=1&_urlVersion=0&_userid=106892&md5=d5e49fe292242eb83201fcddb7e1dc68 [継承]
DOI (任意): 10.1016/S1388-1981(99)00025-6    (→Scopusで検索) [継承]
PMID (任意): 10101265    (→Scopusで検索) [継承]
CRID (任意):
WOS (任意): 000079641400005 [継承]
Scopus (任意): 2-s2.0-0033602463 [継承]
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備考 (任意): 1.(英)   (日) 著者6.確認済 参照不要   [継承]

標準的な表示

和文冊子 ● Takayo Sasagawa, Tatsuzo Oka, Akira Tokumura, Yuriko Nishimoto, Saturnino Munoz, Masashi Kuwahata, Misako Okita, Hideaki Tsuji and Yasuo Natori : Analysis of the fatty acid components in a perchloric acid-soluble protein, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Vol.1437, No.3, 317-324, 1999.
欧文冊子 ● Takayo Sasagawa, Tatsuzo Oka, Akira Tokumura, Yuriko Nishimoto, Saturnino Munoz, Masashi Kuwahata, Misako Okita, Hideaki Tsuji and Yasuo Natori : Analysis of the fatty acid components in a perchloric acid-soluble protein, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Vol.1437, No.3, 317-324, 1999.

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