『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1.新垣 尚捷
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2. (英) Kazi A. Jamil (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3. (英) Kajihara Takehiro (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
4. (英) Ohnishi Tomokazu (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
5. (英) Daikuhara Yasushi (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Hepatocyte growth factor/scatter factor activates the apoptosis signaling pathway by increasing caspase-3 activity in sarcoma 180 cells  (日)    [継承]
副題 (任意):
要約 (任意): (英) Hepatocyte growth factor, which is now known to be the same protein as scatter factor, induced oligonucleosomal fragmentation of nuclear DNA of Sarcoma 180 cells and increased the activity of caspase-3, a key component in control of the apoptotic cell death pathway to about 2.6 times that in control cells on 48 hr incubation, but did not increase the activity of caspase-1. Both HGF-induced DNA fragmentation and caspase-3 activity were completely inhibited by co-incubation with an inhibitor of caspase-3, Ac-DEVD-H. In contrast, HGF did not affect the expression of the apoptosis suppressors Bcl-2 and Bcl-x. These results indicate that HGF activates the apoptosis signaling pathway by increasing caspase-3 activity in Sarcoma 180 cells.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Apoptosis (日) (読) [継承]
3. (英) Caspase 1 (日) (読) [継承]
4. (英) Caspase 3 (日) (読) [継承]
5. (英) Caspases (日) (読) [継承]
6. (英) Cell Survival (日) (読) [継承]
7. (英) Cysteine Endopeptidases (日) (読) [継承]
8. (英) DNA Fragmentation (日) (読) [継承]
9. (英) Enzyme Activation (日) (読) [継承]
10. (英) Enzyme Inhibitors (日) (読) [継承]
11. (英) Gene Expression Regulation, Neoplastic (日) (読) [継承]
12. (英) Hepatocyte Growth Factor (日) (読) [継承]
13. (英) Mice (日) (読) [継承]
14. (英) Neoplasm Proteins (日) (読) [継承]
15. (英) Oligopeptides (日) (読) [継承]
16. (英) Proto-Oncogene Proteins c-bcl-2 (日) (読) [継承]
17. (英) Sarcoma (日) (読) [継承]
18. (英) Signal Transduction (日) (読) [継承]
19. (英) Suppression, Genetic (日) (読) [継承]
20. (英) Tumor Cells, Cultured (日) (読) [継承]
21. (英) bcl-X Protein (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Biochemical and Biophysical Research Communications ([Elsevier])
(pISSN: 0006-291X, eISSN: 1090-2104)

ISSN (任意): 0006-291X
ISSN: 0006-291X (pISSN: 0006-291X, eISSN: 1090-2104)
Title: Biochemical and biophysical research communications
Title(ISO): Biochem Biophys Res Commun
Publisher: Elsevier Inc.
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 245 [継承]
(必須): 1 [継承]
(必須): 211 215 [継承]
都市 (任意):
年月日 (必須): 西暦 1998年 4月 7日 (平成 10年 4月 7日) [継承]
URL (任意):
DOI (任意): 10.1006/bbrc.1998.8397    (→Scopusで検索) [継承]
PMID (任意): 9535810    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意): 000073279400038 [継承]
Scopus (任意): 2-s2.0-0032492547 [継承]
評価値 (任意):
被引用数 (任意):
指導教員 (推奨):
備考 (任意): 1.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Naokatu Arakaki, Jamil A. Kazi, Takehiro Kajihara, Tomokazu Ohnishi and Yasushi Daikuhara : Hepatocyte growth factor/scatter factor activates the apoptosis signaling pathway by increasing caspase-3 activity in sarcoma 180 cells, Biochemical and Biophysical Research Communications, Vol.245, No.1, 211-215, 1998.
欧文冊子 ● Naokatu Arakaki, Jamil A. Kazi, Takehiro Kajihara, Tomokazu Ohnishi and Yasushi Daikuhara : Hepatocyte growth factor/scatter factor activates the apoptosis signaling pathway by increasing caspase-3 activity in sarcoma 180 cells, Biochemical and Biophysical Research Communications, Vol.245, No.1, 211-215, 1998.

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