『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
ID: Pass:

登録内容 (EID=136921)

EID=136921EID:136921, Map:0, LastModified:2017年12月4日(月) 14:07:46, Operator:[[ADMIN]], Avail:TRUE, Censor:0, Owner:[細井 和雄], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.徳島大学.大学院ヘルスバイオサイエンス研究部.生体システム栄養科学部門.栄養医科学講座 (2004年4月1日〜) [継承]
2.徳島大学.大学院ヘルスバイオサイエンス研究部.生体システム栄養科学部門.摂食機能制御学講座 (2004年4月1日〜2015年3月31日) [継承]
著者 (必須): 1. (英) Alizadeh, Mohammad (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2.太田 房雄
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3.細井 和雄
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
4. (英) Kato, Makoto (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
5. (英) Sakai, Tohru (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
6. (英) Satter, A., Mohammed (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Altered allergic cytokine and antibody response in mice treated with Bisphenol A  (日)    [継承]
副題 (任意):
要約 (任意): (英) The objective of this study was to elucidate if Bisphenol A (BPA) administration modulates T helper (Th) cell component of immune responses in a mouse challenged with ovalbumin (OVA), a major food antigen. BALB/c mice, (6 weeks old, female) were orally given either OVA (OVA-fed) or water (Water-fed), immunized intraperitoneally with OVA and injected with either BPA in corn oil or the vehicle alone. After subsequent 2nd immunization, serum titers of total IgE, OVA-specific IgE, IgG, IgG1 IgG2a and ability of their splenocytes for production of interferon (IFN) -gamma, interleukin (IL) -4 and IL-12 were examined by ELISA. Lymphocyte proliferation assay against concanavalin A (Con A) or OVA was also performed for 3H-Thymidine incorporation. In Water-fed groups, treatment with BPA resulted in lower titers of total IgE (P<0.01) and higher levels IgG2a (P<0.05) followed by a higher IFN-gamma (P<0.05) and IL-12 (P<0.05) with an intact IL-4. When OVA-fed groups were examined, the compound did not change production of total and OVA-specific IgE and -IgG2a but resulted in lower production of IFN-gamma (P<0.05). Also, BPA resulted in impaired lymphocyte proliferation to Con A in Water-fed groups (P<0.05) but not in tolerated animals. The findings indicate that BPA results in augmentation of Th1 immune responses but no significant effect on an established tolerance to OVA.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Antibody Formation (日) (読) [継承]
3. (英) Cytokines (日) (読) [継承]
4. (英) Endocrine Disruptors (日) (読) [継承]
5. (英) Lymphocyte Activation (日) (読) [継承]
6. (英) Mice (日) (読) [継承]
7. (英) Mice, Inbred BALB C (日) (読) [継承]
8. (英) Ovalbumin (日) (読) [継承]
9. (英) Phenols (日) (読) [継承]
10. (英) T-Lymphocytes, Helper-Inducer (日) (読) [継承]
発行所 (推奨):
誌名 (必須): The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)

ISSN (任意): 1343-1420
ISSN: 1343-1420 (pISSN: 1343-1420, eISSN: 1349-6867)
Title: The journal of medical investigation : JMI
Title(ISO): J Med Invest
Supplier: 徳島大学
Publisher: Tokushima Daigaku Igakubu
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
[継承]
[継承]
(必須): 53 [継承]
(必須): 1, 2 [継承]
(必須): 70 80 [継承]
都市 (任意): 徳島 (Tokushima/[日本国]) [継承]
年月日 (必須): 西暦 2006年 2月 初日 (平成 18年 2月 初日) [継承]
URL (任意):
DOI (任意): 10.2152/jmi.53.70    (→Scopusで検索) [継承]
PMID (任意): 16537998    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意):
Scopus (任意):
機関リポジトリ : 110790 [継承]
評価値 (任意):
被引用数 (任意):
指導教員 (推奨):
備考 (任意): 1.(英) Article.Affiliation: Department of Preventive Environment and Nutrition, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Mohammad Alizadeh, Fusao Ota, Kazuo Hosoi, Makoto Kato, Tohru Sakai and Mohammed A. Satter : Altered allergic cytokine and antibody response in mice treated with Bisphenol A, The Journal of Medical Investigation : JMI, Vol.53, No.1, 2, 70-80, 2006.
欧文冊子 ● Mohammad Alizadeh, Fusao Ota, Kazuo Hosoi, Makoto Kato, Tohru Sakai and Mohammed A. Satter : Altered allergic cytokine and antibody response in mice treated with Bisphenol A, The Journal of Medical Investigation : JMI, Vol.53, No.1, 2, 70-80, 2006.

関連情報

Number of session users = 0, LA = 0.97, Max(EID) = 377113, Max(EOID) = 1009913.