『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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著者 (必須): 1.前川 正彦
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2. (英) Kamada Masaharu (日) (読)
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3.苛原 稔
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4.山本 哲史
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5. (英) Yoshikawa Shuji (日) (読)
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6. (英) Kasai Yuka (日) (読)
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7. (英) Ohmoto Yasukazu (日) (読)
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8. (英) Gima Hironori (日) (読)
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9. (英) Thaler J Christian (日) (読)
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10.青野 敏博
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題名 (必須): (英) A repertoire of cytokines in human seminal plasma  (日)    [継承]
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要約 (任意): (英) The pathophysiological significance of seminal cytokines in sperm function is still controversial. We determined the repertoire of cytokines in seminal plasma obtained from men with or without abnormalities in semen and assessed the pathophysiological significance of seminal cytokines. After conventional analysis of semen samples obtained from 86 men, levels of seminal cytokines (interleukin [IL]-1alpha, IL-2, IL-4, IL-6, IL-8, tumor necrosis factor-alpha [TNF-alpha], interferon-gamma, granulocyte colony-stimulating factor [G-CSF], macrophage CFS [M-CSF]) and granulocyte elastase were measured by an enzyme-linked immunosorbent assay. Leukocytospermia was defined as seminal plasma, which has > or =1000 ng/ml granulocyte elastase. Leukocytospermia was found in nine of 62 of the subjects in the normozoospermic group but in none of the 24 subjects showing abnormal sperm parameters (azoospermia, n=5; oligozoospermia, n=4; asthenozoospermia, n=15). The IL-8 level in the leukocytospermic group was significantly higher than those in the normal and oligozoospermic groups. IL-1alpha and TNF-alpha levels in the leukocytospermic group were significantly higher than those in the normal and asthenozoospermic groups. Although the G-CSF level in the leukocytospermic group was significantly higher than that in the normal group, high levels of M-CSF were detected in all groups. The IL-8 level was strongly correlated with IL-1alpha (r=0.935, P<0.0001) and G-CSF (r=0.916, P<0.0001) levels. Cytokines detected in seminal plasma are associated with the pathogenesis of leukocytospermia but not with the pathogenesis of asthenozoospermia and oligozoospermia.  (日)    [継承]
キーワード (推奨): 1. (英) Granulocyte elastase (日) (読) [継承]
2. (英) Leukocytospermia (日) (読) [継承]
3. (英) Seminal plasma (日) (読) [継承]
発行所 (推奨): Elsevier (->組織[Elsevier Science]) [継承]
誌名 (必須): Journal of Reproductive Immunology (European Society of Reproductive Immunology)
(pISSN: 0165-0378, eISSN: 1872-7603)

ISSN (任意): 0165-0378
ISSN: 0165-0378 (pISSN: 0165-0378, eISSN: 1872-7603)
Title: Journal of reproductive immunology
Title(ISO): J Reprod Immunol
Publisher: Elsevier Ireland Ltd
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 54 [継承]
(必須): 1-2 [継承]
(必須): 33 42 [継承]
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年月日 (必須): 西暦 2002年 3月 初日 (平成 14年 3月 初日) [継承]
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DOI (任意): 10.1016/S0165-0378(01)00063-8    (→Scopusで検索) [継承]
PMID (任意): 11839394    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Obstetrics and Gynecology, School of Medicine, The University of Tokushima, 3-18-15 Kuramoto-cho, 770-8503, Tokushima, Japan. masahiko@clin.med.tokushima-u.ac.jp  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Masahiko Maegawa, Masaharu Kamada, Minoru Irahara, Satoshi Yamamoto, Shuji Yoshikawa, Yuka Kasai, Yasukazu Ohmoto, Hironori Gima, Christian J Thaler and Toshihiro Aono : A repertoire of cytokines in human seminal plasma, Journal of Reproductive Immunology, Vol.54, No.1-2, 33-42, 2002.
欧文冊子 ● Masahiko Maegawa, Masaharu Kamada, Minoru Irahara, Satoshi Yamamoto, Shuji Yoshikawa, Yuka Kasai, Yasukazu Ohmoto, Hironori Gima, Christian J Thaler and Toshihiro Aono : A repertoire of cytokines in human seminal plasma, Journal of Reproductive Immunology, Vol.54, No.1-2, 33-42, 2002.

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