『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
ID: Pass:

登録内容 (EID=135395)

EID=135395EID:135395, Map:0, LastModified:2013年7月2日(火) 14:25:22, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[山田 博胤], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.徳島大学.病院.診療科.内科 (2003年10月1日〜) [継承]
著者 (必須): 1. (英) Popović B Zoran (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2.山田 博胤 ([徳島大学.大学院医歯薬学研究部.医学域.連携研究部門(医学域).寄附講座系(医学域).地域循環器内科学])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3. (英) Mowrey A Kent (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
4. (英) Zhang Youhua (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
5. (英) Wallick W Don (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
6. (英) Grimm A Richard (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
7. (英) Thomas D James (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
8. (英) Mazgalev N Todor (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Frank-Starling mechanism contributes modestly to ventricular performance during atrial fibrillation  (日)    [継承]
副題 (任意):
要約 (任意): (英) The aim of this study was to assess whether Frank-Starling mechanism has an independent effect on left ventricular (LV) performance in atrial fibrillation (AF). Ventricular performance in AF depends on variable contractility through the interval-force mechanism based on the ratio of preceding and pre-preceding RR intervals (RR(p)/RR(pp)). The impact of end-diastolic volume (EDV) variability, through the Frank-Starling mechanism, is not well understood. We induced AF in 16 open chest dogs. RR intervals, LV pressure, LV volume, and aortic flow were collected for >400 beats during rapid AF (ventricular cycle length 292 +/- 66 ms). In six of the dogs, additional data were collected while average ventricular cycle length was prolonged from 258 +/- 34 ms to 445 +/- 80 ms by selective vagal nerve stimulation of the AV node. The relations of maximal LV power (LVPower) and peak LV pressure derivative (dP/dt) versus RR(p)/RR(pp) were fitted to the equation y = A * (1 - EXP (RR(p)/RR(pp)min - RR(p)/RR(pp))/C) and the residuals (RES) of these relations were analyzed. LVPower and dP/dt strongly correlated with RR(p)/RR(pp) (r(2) = 0.67 +/- 0.12 and 0.66 +/- 0.12, P < .0001 for all correlations). Importantly, RES-LVPower and RES-dP/dt showed linear correlation with EDV (r(2) = 0.20 +/- 0.14 and r(2) = 0.24 +/- 0.17, P < .01 for all correlations). In the six dogs with slowed average ventricular rate, the slope of both residual relationships (RES-LVPower vs EDV and RES- dP/dt vs EDV) decreased (P < .03 for both). The Frank-Starling mechanism contributes to ventricular performance in AF independently of the interval-force effects of the beat-to-beat variability in cardiac contractility. The Frank-Starling mechanism is sensitive to the average ventricular rate.  (日)    [継承]
キーワード (推奨): 1. (英) Atrial fibrillation (日) (読) [継承]
2. (英) Hemodynamics (日) (読) [継承]
3. (英) Preload (日) (読) [継承]
4. (英) Tachyarrhythmia (日) (読) [継承]
5. (英) Contractility (日) (読) [継承]
6. (英) Frank-Starling mechanism (日) (読) [継承]
発行所 (推奨): (英) Heart Rhythm Society (日) (読) [継承]
誌名 (必須): Heart Rhythm (Heart Rhythm Society/Cardiac Electrophysiology Society)
(pISSN: 1547-5271, eISSN: 1556-3871)

ISSN (任意): 1547-5271
ISSN: 1547-5271 (pISSN: 1547-5271, eISSN: 1556-3871)
Title: Heart rhythm
Title(ISO): Heart Rhythm
Publisher: Elsevier BV
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
[継承]
[継承]
(必須): 1 [継承]
(必須): 4 [継承]
(必須): 482 489 [継承]
都市 (任意):
年月日 (必須): 西暦 2004年 10月 初日 (平成 16年 10月 初日) [継承]
URL (任意): http://dx.doi.org/10.1016/j.hrthm.2004.06.016 [継承]
DOI (任意): 10.1016/j.hrthm.2004.06.016    (→Scopusで検索) [継承]
PMID (任意): 15851203    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意): 000226395900015 [継承]
Scopus (任意):
評価値 (任意):
被引用数 (任意):
指導教員 (推奨):
備考 (任意): 1.(英) Article.Affiliation: Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Ohio 44195, USA.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, N.I.H., Extramural  (日)    [継承]
4.(英) Article.PublicationTypeList.PublicationType: Research Support, U.S. Gov't, P.H.S.  (日)    [継承]
5.(英) KeywordList.Keyword: Non-programmatic  (日)    [継承]

標準的な表示

和文冊子 ● Zoran B Popović, Hirotsugu Yamada, Kent A Mowrey, Youhua Zhang, Don W Wallick, Richard A Grimm, James D Thomas and Todor N Mazgalev : Frank-Starling mechanism contributes modestly to ventricular performance during atrial fibrillation, Heart Rhythm, Vol.1, No.4, 482-489, 2004.
欧文冊子 ● Zoran B Popović, Hirotsugu Yamada, Kent A Mowrey, Youhua Zhang, Don W Wallick, Richard A Grimm, James D Thomas and Todor N Mazgalev : Frank-Starling mechanism contributes modestly to ventricular performance during atrial fibrillation, Heart Rhythm, Vol.1, No.4, 482-489, 2004.

関連情報

Number of session users = 4, LA = 0.51, Max(EID) = 382699, Max(EOID) = 1022094.