『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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登録内容 (EID=135309)

EID=135309EID:135309, Map:0, LastModified:2013年4月30日(火) 21:22:07, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[山田 博胤], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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カテゴリ (推奨):
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学究種別 (推奨):
組織 (推奨): 1.徳島大学.病院.診療科.内科 (2003年10月1日〜) [継承]
著者 (必須): 1.山田 博胤 ([徳島大学.大学院医歯薬学研究部.医学域.連携研究部門(医学域).寄附講座系(医学域).地域循環器内科学])
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2. (英) Mowrey A. Kent (日) (読)
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[継承]
3. (英) Popović B. Zoran (日) (読)
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[継承]
4. (英) Martin O. David (日) (読)
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[継承]
5. (英) Thomas D. James (日) (読)
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[継承]
6. (英) Wallick W. Don (日) (読)
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[継承]
題名 (必須): (英) Coupled pacing improves cardiac efficiency during acute atrial fibrillation with or without cardiac depression  (日)    [継承]
副題 (任意):
要約 (任意): (英) Coupled pacing (CP), a method for controlling ventricular rate during atrial fibrillation (AF), consists of a single electrical stimulation applied to the ventricles after each spontaneous activation. CP results in a mechanical contraction rate approximately one-half the rate during AF. Paired stimulation in which two electrical stimuli are delivered to the ventricles has also been proposed as a therapy for heart failure. Although paired stimulation enhances contractility, it greatly increases energy consumption. The primary hypothesis of the present study is that CP improves cardiac function during acute AF without a similar increase in energy consumption because of the reduced rate of ventricular contractions. In a canine model, CP was applied during four stages: sinus rhythm (SR), acute AF, cardiac dysfunction (CD), and AF in the presence of cardiac dysfunction. The rate of ventricular contraction decreased in all four stages as the result of CP. In addition, we determined the changes in external cardiac work, myocardial oxygen consumption, and myocardial efficiency in the each of four stages. CP partially reversed the effects of AF and CD on external cardiac work, whereas myocardial oxygen consumption increased only moderately. In all stages but SR, CP increased myocardial efficiency because of the marked increases in cardiac work compared with the moderate increases in total energy consumed. Thus this pacing therapy may be a viable therapy for patients with concurrent atrial fibrillation and heart failure.  (日)    [継承]
キーワード (推奨): 1. (英) Acute Disease (日) (読) [継承]
2. (英) Animals (日) (読) [継承]
3. (英) Atrial Fibrillation (日) (読) [継承]
4. (英) Cardiac Pacing, Artificial (日) (読) [継承]
5. (英) Dogs (日) (読) [継承]
6. (英) Electrocardiography (日) (読) [継承]
7. (英) Heart (日) (読) [継承]
8. (英) Myocardial Contraction (日) (読) [継承]
9. (英) Myocardium (日) (読) [継承]
10. (英) Oxygen Consumption (日) (読) [継承]
11. (英) Ventricular Function (日) (読) [継承]
発行所 (推奨): アメリカ生理学会 [継承]
誌名 (必須): American Journal of Physiology, Heart and Circulatory Physiology ([アメリカ生理学会])
(pISSN: 0363-6135, eISSN: 1522-1539)

ISSN (任意): 0363-6135
ISSN: 0363-6135 (pISSN: 0363-6135, eISSN: 1522-1539)
Title: American journal of physiology. Heart and circulatory physiology
Title(ISO): Am J Physiol Heart Circ Physiol
Publisher: American Physiological Society
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 287 [継承]
(必須): 5 [継承]
(必須): H2016 H2022 [継承]
都市 (任意):
年月日 (必須): 西暦 2004年 11月 初日 (平成 16年 11月 初日) [継承]
URL (任意): http://ajpheart.physiology.org/cgi/content/abstract/287/5/H2016 [継承]
DOI (任意): 10.1152/ajpheart.00347.2004    (→Scopusで検索) [継承]
PMID (任意): 15284067    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Ave., Cleveland, OH 44195, USA.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]
4.(英) Article.PublicationTypeList.PublicationType: Validation Studies  (日)    [継承]

標準的な表示

和文冊子 ● Hirotsugu Yamada, Kent A. Mowrey, Zoran B. Popović, David O. Martin, James D. Thomas and Don W. Wallick : Coupled pacing improves cardiac efficiency during acute atrial fibrillation with or without cardiac depression, American Journal of Physiology, Heart and Circulatory Physiology, Vol.287, No.5, H2016-H2022, 2004.
欧文冊子 ● Hirotsugu Yamada, Kent A. Mowrey, Zoran B. Popović, David O. Martin, James D. Thomas and Don W. Wallick : Coupled pacing improves cardiac efficiency during acute atrial fibrillation with or without cardiac depression, American Journal of Physiology, Heart and Circulatory Physiology, Vol.287, No.5, H2016-H2022, 2004.

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