『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=134420EID:134420, Map:0, LastModified:2016年7月22日(金) 14:36:04, Operator:[三好 小文], Avail:TRUE, Censor:0, Owner:[勢井 宏義], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
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カテゴリ (推奨):
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学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Sakata Mie (日) (読)
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2.勢井 宏義 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.生理系.統合生理学])
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3.樋田 一徳
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4.藤原 広明
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5. (英) Urushihara Ryo (日) (読)
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6.森田 雄介
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題名 (必須): (英) Mesolimbic dopaminergic system is involved in diurnal blood pressure regulation  (日)    [継承]
副題 (任意):
要約 (任意): (英) Parkinson's disease (PD) patients with autonomic failure show no nocturnal decrease in blood pressure (BP). At present, it is not clear if this symptom is attributable to the disturbance of the dopaminergic (DA) system that is responsible for PD. In the present study, we determined that the mesolimbic DA system is involved in diurnal profiles of the mean BP (MBP) by destroying the A10 DA system in rats with 6-hydroxydopamine. In control rats, a clear dip in the MBP and heart rate (HR) occurs during the light, that is, resting period, analogous to the nocturnal dip in normal humans. This normal daytime decrease in MBP and HR was disturbed by inducing a lesion of the ventral tegmental area (VTA) DA neurons, although the rhythms of wake-sleep duration and behavioral activity remained relatively intact. On the basis of this evidence, the absence of a nocturnal dip in BP in PD patients is attributed to impairment of the mesolimbic DA system.  (日)    [継承]
キーワード (推奨): 1.血圧 (blood pressure) [継承]
2. (英) heart rate (日) (読) [継承]
3. (英) nocturnal dip (日) (読) [継承]
4. (英) Non-dipper (日) (読) [継承]
5. (英) ventral tegmental area (日) (読) [継承]
6.ドーパミン (dopamine) [継承]
7. (英) 6-hydroxydopamine (日) (読) [継承]
8.ラット (rat) [継承]
発行所 (推奨): Elsevier (->組織[Elsevier Science]) [継承]
誌名 (必須): Brain Research ([Elsevier Science])
(pISSN: 0006-8993, eISSN: 1872-6240)

ISSN (任意): 0006-8993
ISSN: 0006-8993 (pISSN: 0006-8993, eISSN: 1872-6240)
Title: Brain research
Title(ISO): Brain Res.
Publisher: Elsevier BV
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 928 [継承]
(必須): 1-2 [継承]
(必須): 194 201 [継承]
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年月日 (必須): 西暦 2002年 2月 22日 (平成 14年 2月 22日) [継承]
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DOI (任意): 10.1016/S0006-8993(01)03402-3    (→Scopusで検索) [継承]
PMID (任意): 11844487    (→Scopusで検索) [継承]
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WOS (任意): 000174374800022 [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Physiology, School of Medicine, The University of Tokushima, Tokushima 770-8503, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Mie Sakata, Hiroyoshi Sei, Kazunori Toida, Hiroaki Fujihara, Ryo Urushihara and Yusuke Morita : Mesolimbic dopaminergic system is involved in diurnal blood pressure regulation, Brain Research, Vol.928, No.1-2, 194-201, 2002.
欧文冊子 ● Mie Sakata, Hiroyoshi Sei, Kazunori Toida, Hiroaki Fujihara, Ryo Urushihara and Yusuke Morita : Mesolimbic dopaminergic system is involved in diurnal blood pressure regulation, Brain Research, Vol.928, No.1-2, 194-201, 2002.

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Number of session users = 0, LA = 0.54, Max(EID) = 362759, Max(EOID) = 970276.