『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=134417EID:134417, Map:0, LastModified:2017年5月26日(金) 15:36:09, Operator:[三好 小文], Avail:TRUE, Censor:0, Owner:[勢井 宏義], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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著者 (必須): 1.勢井 宏義 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.生理系.統合生理学])
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2.佐野 敦子
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3. (英) Ohno Hiromi (日) (読)
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4. (英) Yamabe Kazue (日) (読)
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5.西岡 安彦 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.呼吸器・膠原病内科学])
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6.曽根 三郎
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7.森田 雄介
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題名 (必須): (英) Age-related changes in control of blood pressure and heart rate during sleep in the rat  (日)    [継承]
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要約 (任意): (英) The aim of this study was to determine age-related changes in the control of mean arterial pressure (MAP) and heart rate (HR) during sleep, and its relationship to the baroreflex in aging. MAP, HR, body temperature (TP), spontaneous activity (ACT), and sleeping/waking duration were monitored for 24 hours in groups of young (10-12 wk old) and old (23-24 mo old) rats. The sleep laboratory at the University of Tokushima. Subjects were 8 young (10-12 wk old) and 7 old (23-24 mo old) Wistar rats. Reflex control of HR was evaluated by examining various pressure responses to an intravenous bolus injection of phenylephrine and sodium nitroprusside. MAP and TP were recorded by a radiotelemetry system. HR was detected from the AP signal. ACT was counted by a photo-sensor system. In the case of old rats, the sensitivity of baroreflex control of HR was significantly depressed, and the spontaneous increase of MAP and HR during REM sleep and the MAP drop at the end of REM sleep were significantly enhanced. The old rats showed no large deterioration of the circadian profiles of MAP, HR, TP, and the amount of sleep. The baroreflex dysfunction is considered to appear in an early stage of the aging process, and to affect the control of MAP and HR during sleep.  (日)    [継承]
キーワード (推奨): 1.加齢 (aging/->キーワード[老化]) [継承]
2. (英) rat (日) (読) [継承]
3. (英) arterial pressure (日) (読) [継承]
4. (英) heart rate (日) (読) [継承]
5.睡眠 (sleep) [継承]
発行所 (推奨):
誌名 (必須): Sleep (Associated Professional Sleep Societies)
(pISSN: 0161-8105, eISSN: 1550-9109)

ISSN (任意): 0161-8105
ISSN: 0161-8105 (pISSN: 0161-8105, eISSN: 1550-9109)
Title: Sleep
Title(ISO): Sleep
Publisher: Oxford University Press
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 25 [継承]
(必須): 3 [継承]
(必須): 279 285 [継承]
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年月日 (必須): 西暦 2002年 5月 1日 (平成 14年 5月 1日) [継承]
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PMID (任意): 12003158    (→Scopusで検索) [継承]
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Scopus (任意): 2-s2.0-0036570598 [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Physiology, School of Medicine, The University of Tokushima, Japan. sei@basic.med.tokushima-u.ac.jp  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Hiroyoshi Sei, Atsuko Sano, Hiromi Ohno, Kazue Yamabe, Yasuhiko Nishioka, Saburo Sone and Yusuke Morita : Age-related changes in control of blood pressure and heart rate during sleep in the rat, Sleep, Vol.25, No.3, 279-285, 2002.
欧文冊子 ● Hiroyoshi Sei, Atsuko Sano, Hiromi Ohno, Kazue Yamabe, Yasuhiko Nishioka, Saburo Sone and Yusuke Morita : Age-related changes in control of blood pressure and heart rate during sleep in the rat, Sleep, Vol.25, No.3, 279-285, 2002.

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