『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
ID: Pass:

登録内容 (EID=132367)

EID=132367EID:132367, Map:0, LastModified:2017年4月19日(水) 14:15:55, Operator:[三好 小文], Avail:TRUE, Censor:0, Owner:[植野 哲], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.徳島大学.医学部.保健学科.検査技術科学専攻.機能系検査学講座 [継承]
著者 (必須): 1.福澤 健治
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2.德村 彰
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3.小暮 健太朗 ([徳島大学.大学院医歯薬学研究部.薬学域.薬科学部門.創薬科学系.衛生薬学])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
4. (英) Iemura Masahito (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
5. (英) Gondoh Naoto (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
6.藤井 正信
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
7.植野 哲 ([徳島大学.大学院医歯薬学研究部.薬学域.薬科学部門.総合薬学教育学系.総合薬学研究推進学])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
8.柴田 瑩
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) A comparative study of the ability of ferric nitrilotriacetate and other iron chelators to assist membrane lipid peroxidation by superoxide radicals  (日)    [継承]
副題 (任意):
要約 (任意): (英) This study examined some of the variables determining the efficiency of lipid peroxidation in egg yolk phosphatidylcholine liposomes and in microsomes exposed to enzymatically-generated superoxide radicals. The initiation of peroxidation required the presence of preformed lipid peroxides and a chelated metal catalyst. Comparison of the relative effectiveness of four iron chelating agents showed that the chelate must bind to the membrane by coulombic attraction between the charged membrane and a chelate carrying an opposite net charge. Of the chelates tested, only the carcinogenic ferric nitrilotriacetate [corrected] (Fe(3+)-NTA) was an effective catalyst of oxidation of all membranes, whether carrying a net charge, or not. We postulate that the unique catalytic capacity of the ferric nitrilotriacetate [corrected] (Fe(3+)-NTA) can be explained by its existence in two forms at neutral pH, each binding to oppositely charged membranes and initiating their peroxidation. This gives the complex the unique ability to bind to any membrane, which may be a factor in its carcinogenicity.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Ascorbic Acid (日) (読) [継承]
3. (英) Carcinogens (日) (読) [継承]
4. (英) Ferric Compounds (日) (読) [継承]
5. (英) Hydrogen-Ion Concentration (日) (読) [継承]
6. (英) Iron Chelating Agents (日) (読) [継承]
7. (英) Lipid Peroxidation (日) (読) [継承]
8. (英) Liposomes (日) (読) [継承]
9. (英) Male (日) (読) [継承]
10. (英) Microsomes, Liver (日) (読) [継承]
11. (英) NADP (日) (読) [継承]
12. (英) Nitrilotriacetic Acid (日) (読) [継承]
13. (英) Oxidation-Reduction (日) (読) [継承]
14. (英) Oxygen (日) (読) [継承]
15. (英) Phosphatidylcholines (日) (読) [継承]
16. (英) Rats (日) (読) [継承]
17. (英) Rats, Wistar (日) (読) [継承]
18. (英) Superoxides (日) (読) [継承]
19. (英) Thiobarbituric Acid Reactive Substances (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Chemistry and Physics of Lipids ([Elsevier Science])
(pISSN: 0009-3084, eISSN: 1873-2941)

ISSN (任意): 0009-3084
ISSN: 0009-3084 (pISSN: 0009-3084, eISSN: 1873-2941)
Title: Chemistry and physics of lipids
Title(ISO): Chem Phys Lipids
Publisher: Elsevier BV
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
[継承]
[継承]
(必須): 110 [継承]
(必須): 1 [継承]
(必須): 69 84 [継承]
都市 (任意):
年月日 (必須): 西暦 2001年 3月 初日 (平成 13年 3月 初日) [継承]
URL (任意):
DOI (任意):
PMID (任意): 11245836    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意):
Scopus (任意):
評価値 (任意):
被引用数 (任意):
指導教員 (推奨):
備考 (任意): 1.(英) Article.PublicationTypeList.PublicationType: Comparative Study  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Kenji Fukuzawa, Akira Tokumura, Kentaro Kogure, Masahito Iemura, Naoto Gondoh, Masanobu Fujii, Satoru Ueno and Akira Shibata : A comparative study of the ability of ferric nitrilotriacetate and other iron chelators to assist membrane lipid peroxidation by superoxide radicals, Chemistry and Physics of Lipids, Vol.110, No.1, 69-84, 2001.
欧文冊子 ● Kenji Fukuzawa, Akira Tokumura, Kentaro Kogure, Masahito Iemura, Naoto Gondoh, Masanobu Fujii, Satoru Ueno and Akira Shibata : A comparative study of the ability of ferric nitrilotriacetate and other iron chelators to assist membrane lipid peroxidation by superoxide radicals, Chemistry and Physics of Lipids, Vol.110, No.1, 69-84, 2001.

関連情報

Number of session users = 0, LA = 1.84, Max(EID) = 383263, Max(EOID) = 1024353.