| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○組織 (推奨): | 1. | 徳島大学.総合科学部.養護教員養成充実化プログラム (2005年4月1日〜2008年3月31日)
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| 2. | 徳島大学.大学院ヘルスバイオサイエンス研究部.生体システム栄養科学部門.医療栄養科学講座 (2004年4月1日〜)
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| 3. | 徳島大学.大学院ヘルスバイオサイエンス研究部.発達予防医歯学部門.病態予防医学講座 (2004年4月1日〜)
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| ○著者 (必須): | 1. | (英) Kondo Noriyasu (日) (読)
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| 2. | 野村 昌弘
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| 3. | 中屋 豊
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| 4. | 伊東 進
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| 5. | (英) Ohguro Takashi (日) (読)
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| ○題名 (必須): | □ | (英) Association of Inflammatory Marker and Highly Sensitive C-Reactive Protein With Aerobic Exercise Capacity, Maximum Oxygen Uptake and Insulin Resistance in Healthy Middle-Aged Volunteers (日)
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| ○要約 (任意): | □ | (英) Increased levels of inflammation markers, such as C-reactive protein (CRP) and tumor necrosis factor-alpha , have been found in insulin resistance syndrome. Those with elevated levels of high-sensitive CRP (hs-CRP) are at a higher risk for coronary heart disease. In the present study, we evaluated whether maximum oxygen uptake and insulin resistance are related to hs-CRP for the primary prevention of coronary heart disease. The subjects were 50 subjects who did not have diabetes mellitus. A multi-step treadmill exercise test was performed to obtain the maximum oxygen uptake when assessed by computerized breath-by-breath analysis. As an index of insulin resistance, the homeostasis model insulin resistance index (HOMA-R; fasting glucose x fasting insulin/405) was used. In addition, bodyweight, body mass index, subcutaneous fat thickness, total cholesterol, high-density lipoprotein (HDL) cholesterol, and triglyceride were measured. Multivariate analysis revealed that hs-CRP was significantly correlated with HDL-cholesterol, uric acid, gamma-glutamyl transpeptidase and maximum oxygen uptake. The maximum oxygen uptake showed the smallest odds ratio was in terms of the relationship with hs-CRP. The present study suggests that the development of exercising habits increases the maximum oxygen uptake. Furthermore, an elevated maximum oxygen uptake decreases HOMA-R and reduces the inflammatory marker CRP, suggesting that exercising habit plays an important role in the primary prevention of coronary heart disease. (日)
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| ○キーワード (推奨): | 1. | (英) Exercising habits (日) (読)
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| 2. | (英) High-sensitive C-reactive protein (日) (読)
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| 3. | インスリン抵抗性 (insulin resistance)
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| 4. | (英) Maximum oxygen uptake (日) (読)
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| ○発行所 (推奨): | □ | 社団法人 日本循環器学会
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| ○誌名 (必須): | □ | Circulation Journal ([社団法人 日本循環器学会])
(pISSN: 1346-9843, eISSN: 1347-4820)
| ○ISSN (任意): | □ | 1346-9843
ISSN: 1346-9843
(pISSN: 1346-9843, eISSN: 1347-4820) Title: Circulation journal : official journal of the Japanese Circulation SocietyTitle(ISO): Circ JSupplier: 社団法人日本循環器学会Publisher: Japanese Circulation Society (NLM Catalog)
(Webcat Plus)
(医中誌Web)
(J-STAGE)
(Scopus)
(CrossRef)
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| ○巻 (必須): | □ | 69
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| ○号 (必須): | □ | 4
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| ○頁 (必須): | □ | 452 457
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2005年 4月 初日 (平成 17年 4月 初日)
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| ○URL (任意): | □ | http://www.jstage.jst.go.jp/article/circj/69/4/69_452/_article
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| ○DOI (任意): | □ | 10.1253/circj.69.452 (→Scopusで検索)
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| ○PMID (任意): | □ | 15791041 (→Scopusで検索)
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| ○Scopus (任意): | □ | 2-s2.0-17044408083
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| ○備考 (任意): | 1. | (英) Article.Affiliation: Department of Health Examination, Kochi Red Cross Hospital, Kochi, Japan. (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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