○種別 (必須): | □ | 学術論文 (審査論文)
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○言語 (必須): | □ | 英語
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○招待 (推奨): |
○審査 (推奨): |
○カテゴリ (推奨): |
○共著種別 (推奨): |
○学究種別 (推奨): |
○組織 (推奨): |
○著者 (必須): | 1. | (英) Niwa Mineo (日) (読)
○役割 (任意): |
○貢献度 (任意): |
○学籍番号 (推奨): |
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| 2. | (英) Tsutsumishita Yasuyuki (日) (読)
○役割 (任意): |
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○学籍番号 (推奨): |
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| 3. | (英) Kawai Yumiko (日) (読)
○役割 (任意): |
○貢献度 (任意): |
○学籍番号 (推奨): |
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| 4. | (英) Takahara Hideo (日) (読)
○役割 (任意): |
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○学籍番号 (推奨): |
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| 5. | (英) Nakamura Noriko (日) (読)
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○学籍番号 (推奨): |
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| 6. | (英) Futaki Shiroh (日) (読)
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○学籍番号 (推奨): |
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| 7. | 高石 喜久 ([徳島大学.デザイン型AI教育研究センター])
○役割 (任意): |
○貢献度 (任意): |
○学籍番号 (推奨): |
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| 8. | (英) Kondoh Wataru (日) (読)
○役割 (任意): |
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○学籍番号 (推奨): |
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| 9. | (英) Moritoki Hideki (日) (読)
○役割 (任意): |
○貢献度 (任意): |
○学籍番号 (推奨): |
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○題名 (必須): | □ | (英) Suppression of Inducible Nitric Oxide Synthase mRNA Expression by Tryptoquinone A (日)
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○副題 (任意): |
○要約 (任意): | □ | (英) Triptoquinone A (TQA), which is an anti-inflammatory constituent in plants, was studied for its suppressive effect on nitric oxide production by LPS. TQA significantly suppressed smooth muscle relaxation and increase in cyclic GMP levels by nitric oxide (NO) in an L-arginine-induced relaxation experiment. The mechanistic studies showed that TQA did not directly inhibit NO radicals and inducible nitric oxide synthase (iNOS) enzyme but suppressed IL-1 beta and iNOS mRNA expression by LPS. The suppression level of iNOS gene expression by TQA was comparable to that by dexamethasone. TQA may be a useful candidate for the development of a drug as a potent inhibitor of iNOS gene over-expression. (日)
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○キーワード (推奨): | 1. | (英) Animals (日) (読)
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| 2. | (英) Anti-Inflammatory Agents, Non-Steroidal (日) (読)
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| 3. | (英) Aorta, Thoracic (日) (読)
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| 4. | (英) Arginine (日) (読)
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| 5. | (英) Base Sequence (日) (読)
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| 6. | (英) Cyclic GMP (日) (読)
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| 7. | (英) DNA Primers (日) (読)
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| 8. | (英) Dexamethasone (日) (読)
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| 9. | (英) Diterpenes (日) (読)
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| 10. | (英) Gene Expression Regulation, Enzymologic (日) (読)
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| 11. | (英) Interleukin-1 (日) (読)
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| 12. | (英) Isoenzymes (日) (読)
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| 13. | (英) Kinetics (日) (読)
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| 14. | (英) Male (日) (読)
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| 15. | (英) Molecular Sequence Data (日) (読)
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| 16. | (英) Muscle Relaxation (日) (読)
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| 17. | (英) Muscle, Smooth, Vascular (日) (読)
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| 18. | (英) Nitric Oxide Synthase (日) (読)
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| 19. | (英) Nitroprusside (日) (読)
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| 20. | (英) Phenylephrine (日) (読)
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| 21. | (英) Plants (日) (読)
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| 22. | (英) Polymerase Chain Reaction (日) (読)
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| 23. | (英) RNA, Messenger (日) (読)
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| 24. | (英) Rats (日) (読)
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| 25. | (英) Rats, Wistar (日) (読)
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| 26. | (英) Time Factors (日) (読)
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| 27. | (英) Transcription, Genetic (日) (読)
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| 28. | (英) Vasodilator Agents (日) (読)
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○発行所 (推奨): | □ | Academic Press (->組織[Elsevier Science])
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○誌名 (必須): | □ | Biochemical and Biophysical Research Communications ([Elsevier])
(pISSN: 0006-291X, eISSN: 1090-2104)
○ISSN (任意): | □ | 0006-291X
ISSN: 0006-291X
(pISSN: 0006-291X, eISSN: 1090-2104) Title: Biochemical and biophysical research communicationsTitle(ISO): Biochem Biophys Res CommunPublisher: Elsevier B.V. (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login])
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○巻 (必須): | □ | 224
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○号 (必須): | □ | 2
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○頁 (必須): | □ | 579 585
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○都市 (任意): |
○年月日 (必須): | □ | 西暦 1996年 6月 16日 (平成 8年 6月 16日)
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○URL (任意): | □ | http://dx.doi.org/10.1006/bbrc.1996.1067
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○DOI (任意): | □ | 10.1006/bbrc.1996.1067 (→Scopusで検索)
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○PMID (任意): | □ | 8702429 (→Scopusで検索)
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○備考 (任意): | 1. | (英) Article.Affiliation: Faculty of Pharmaceutical Sciences, University of Tokushima, Japan. mniwa@ph.tokushima-u.ac.ip (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: In Vitro (日)
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| 3. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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