| ○種別 (必須): | □ | 学術論文 (審査論文)
| [継承] |
| ○言語 (必須): | □ | 英語
| [継承] |
| ○招待 (推奨): |
| ○審査 (推奨): |
| ○カテゴリ (推奨): |
| ○共著種別 (推奨): |
| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Yesilada Erdem (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 2. | (英) Deliorman Didem (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 3. | (英) Ergun Fatma (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 4. | 高石 喜久 ([徳島大学.デザイン型AI教育研究センター])
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 5. | (英) Ono Yukihisa (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| ○題名 (必須): | □ | (英) Effects of the Turkish subspecies of Viscum album on macrophage-derived cytokines (日)
| [継承] |
| ○副題 (任意): |
| ○要約 (任意): | □ | (英) Viscum album L. herbs are used for the treatment of various diseases. Apart from their immunostimulatory, antitumor, and hypotension inducing activities, anti-inflammatory effects has also been recorded in the literature. Since the immunostimulatory activity of mistletoe is mainly attributed to a stimulation of the mononuclear phagocytic system and to an induction of inflammation by macrophage-derived cytokines, utilization based on anti-inflammatory activity seems in contrast with its use as immunostimulant. The inhibitory effects of 80% ethanol extracts and subfractions obtained by petroleum ether, diethylether, ethylacetate and n-butanol from three Turkish subspecies of V. album L. (ssp. album, ssp. abietis, ssp. austriacum) against interleukins (IL-1alpha and IL-1beta) and tumor necrosis factor-alpha were studied. Ethanolic (80%) extracts of all three subspecies exhibited almost no significant inhibitory activity on the proinflammatory cytokines, at least in the concentrations applied in this study. In contrast, they induce a concentration dependent stimulation of these cytokines. On the other hand, moderate to weak, dose dependent inhibitory effects were observed on fractionation, which may be attributed to the existence of less polar components with anti-inflammatory activity. Based on our results, it was concluded that the utilization of ethanol extracts for anti-inflammatory purposes would not be beneficial probably due to the partial extraction of the low-molecular-weight polypeptides, i.e. viscotoxins, which induce an inflammatory response. Moreover, for anti-inflammatory effects, extracts of Viscum album ssp. austriacum may be preferred, since higher inhibitory ratios were obtained against inflammatory cytokines than with the other two subspecies. (日)
| [継承] |
| ○キーワード (推奨): | 1. | (英) Interleukin-1α (日) (読)
| [継承] |
| 2. | (英) Interleukin-1β (日) (読)
| [継承] |
| 3. | (英) Loranthaceae (日) (読)
| [継承] |
| 4. | (英) Mistletoe (日) (読)
| [継承] |
| 5. | (英) Tumor necrosis factor-α (日) (読)
| [継承] |
| 6. | (英) Viscum album ssp. abietis (日) (読)
| [継承] |
| 7. | (英) Viscum album ssp.album (日) (読)
| [継承] |
| 8. | (英) Viscum album ssp. austriacum (日) (読)
| [継承] |
| ○発行所 (推奨): | □ | (英) Elsevier Science Ireland Ltd. (日) (読)
| [継承] |
| ○誌名 (必須): | □ | Journal of Ethnopharmacology ([Elsevier Science])
(pISSN: 0378-8741, eISSN: 1872-7573)
| ○ISSN (任意): | □ | 0378-8741
ISSN: 0378-8741
(pISSN: 0378-8741, eISSN: 1872-7573) Title: Journal of ethnopharmacologyTitle(ISO): J EthnopharmacolPublisher: Elsevier Ireland Ltd (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
| [継承] |
| ○巻 (必須): | □ | 61
| [継承] |
| ○号 (必須): | □ | 3
| [継承] |
| ○頁 (必須): | □ | 195 200
| [継承] |
| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 1998年 7月 初日 (平成 10年 7月 初日)
| [継承] |
| ○URL (任意): | □ | http://dx.doi.org/10.1016/S0378-8741(98)00038-5
| [継承] |
| ○DOI (任意): | □ | 10.1016/S0378-8741(98)00038-5 (→Scopusで検索)
| [継承] |
| ○PMID (任意): | □ | 9705010 (→Scopusで検索)
| [継承] |
| ○CRID (任意): |
| ○WOS (任意): |
| ○Scopus (任意): |
| ○評価値 (任意): |
| ○被引用数 (任意): |
| ○指導教員 (推奨): |
| ○備考 (任意): | 1. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
| [継承] |