『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=124380EID:124380, Map:0, LastModified:2012年8月31日(金) 19:22:37, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[有持 秀喜], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.大学院ヘルスバイオサイエンス研究部.神経情報医学部門.病態情報医学講座 (2004年4月1日〜) [継承]
著者 (必須): 1.森田 恭二
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2.有持 秀喜 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.病理系.生体防御医学])
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3. (英) Yoshida Sigeru (日) 吉田 繁 (読) よしだ しげる
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題名 (必須): (英) Down-regulation of immediate early gene egr-1 expression in rat C6 glioma cells by short-term exposure to high salt culture medium.  (日)    [継承]
副題 (任意):
要約 (任意): (英) Influence of high salt culture conditions on the expression of immediate early gene egr-1 in rat C6 glioma cells was investigated by measuring both Egr-1 mRNA and protein levels in the cells exposed to the medium containing high concentrations of NaCl. The exposure to high salt medium reduced Egr-1 mRNA and protein levels, while Egr-1 mRNA levels were not altered by the medium containing either sucrose or glycerol. Veratridine and monensin also reduced Egr-1 mRNA levels, similar in extent to that induced by high salt medium. Imaging analysis indicated that the exposure to high salt medium induced the elevation of Na+ levels within the cells. These results indicate that neither hyperosmotic pressure nor ionic strength of high salt medium contribute to the reduction of Egr-1 expression, and suggest that the elevation of intracellular Na+ concentration is closely associated with the down-regulation of egr-1 gene expression.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Calcium (日) (読) [継承]
3. (英) Cell Line, Tumor (日) (読) [継承]
4. (英) Culture Media (日) (読) [継承]
5. (英) DNA-Binding Proteins (日) (読) [継承]
6. (英) Down-Regulation (日) (読) [継承]
7. (英) Early Growth Response Protein 1 (日) (読) [継承]
8. (英) Gene Expression Regulation (日) (読) [継承]
9. (英) Genes, Immediate-Early (日) (読) [継承]
10. (英) Glioma (日) (読) [継承]
11. (英) Immediate-Early Proteins (日) (読) [継承]
12. (英) Monensin (日) (読) [継承]
13. (英) Osmolar Concentration (日) (読) [継承]
14. (英) Rats (日) (読) [継承]
15. (英) Saline Solution, Hypertonic (日) (読) [継承]
16. (英) Sodium (日) (読) [継承]
17. (英) Transcription Factors (日) (読) [継承]
18. (英) Veratridine (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Cell Biology International (International Federation for Cell Biology)
(pISSN: 1065-6995, eISSN: 1095-8355)

ISSN (任意): 1065-6995
ISSN: 1065-6995 (pISSN: 1065-6995, eISSN: 1095-8355)
Title: Cell biology international
Title(ISO): Cell Biol. Int.
Supplier: International Federation for Cell Biology
Publisher: Blackwell
 (NLM Catalog  (Wiley  (Scopus  (CrossRef (Scopus information is found. [need login])
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年月日 (必須): 西暦 2005年 4月 初日 (平成 17年 4月 初日) [継承]
URL (任意):
DOI (任意): 10.1016/j.cellbi.2005.01.002    (→Scopusで検索) [継承]
PMID (任意): 15905107    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Pharmacology, Tokushima University School of Medicine, 3-18-15 Kuramoto, Tokushima 770-8503, Japan. km@basic.med.tokushima-u.ac.jp  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Kyoji Morita, Hideki Arimochi and Sigeru Yoshida : Down-regulation of immediate early gene egr-1 expression in rat C6 glioma cells by short-term exposure to high salt culture medium., Cell Biology International, Vol.29, No.4, 261-268, 2005.
欧文冊子 ● Kyoji Morita, Hideki Arimochi and Sigeru Yoshida : Down-regulation of immediate early gene egr-1 expression in rat C6 glioma cells by short-term exposure to high salt culture medium., Cell Biology International, Vol.29, No.4, 261-268, 2005.

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