『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=124346EID:124346, Map:0, LastModified:2016年9月9日(金) 14:34:12, Operator:[三木 ちひろ], Avail:TRUE, Censor:0, Owner:[[学科長]/[徳島大学.歯学部.歯学科]], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Hino Satoshi (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2. (英) Kawamata Hitoshi (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3.内田 大亮
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学籍番号 (推奨):
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4.表原 文江
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学籍番号 (推奨):
[継承]
5. (英) Miwa Yoshihiro (日) (読)
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学籍番号 (推奨):
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6. (英) Begum Nasima Mila (日) (読)
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学籍番号 (推奨):
[継承]
7.吉田 秀夫
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学籍番号 (推奨):
[継承]
8.佐藤 光信
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学籍番号 (推奨):
[継承]
題名 (必須): (英) Nuclear translocation of TSC-22 (TGF-beta-stimulated clone-22) concomitant with apoptosis: TSC-22 as a putative transcriptional regulator  (日)    [継承]
副題 (任意):
要約 (任意): (英) We examined the alteration of the subcellular localization of TSC-22 (TGF-beta-stimulated clone-22) after induction of apoptosis and the transcription-regulatory activity of TSC-22. In the living cells, TSC-22-green fluorescent protein (GFP) fusion protein was clearly localized to the cytoplasm, however, in the apoptotic cells, the TSC-22-GFP fusion protein was translocated from the cytoplasm to the nucleus. TSC-22 fused to GAL4-DNA binding domain (GAL4BD) did not show the transcriptional activity on the reporter genes in yeast and in HSG (salivary gland cancer cells) and Hela. However, in CHO cells, TSC-22-GAL4BD fusion protein strongly activated the reporter gene. The transcriptional activity of the leucine zipper structure of TSC-22 is greater than that of the full-length TSC-22. These findings suggest that after receiving the apoptotic stimuli, TSC-22 translocates from the cytoplasm to the nucleus and shows the transcription-regulatory activity.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2.アポトーシス (apoptosis) [継承]
3. (英) CHO Cells (日) (読) [継承]
4. (英) Cell Nucleus (日) (読) [継承]
5. (英) Cricetinae (日) (読) [継承]
6. (英) Cytoplasm (日) (読) [継承]
7. (英) DNA-Binding Proteins (日) (読) [継承]
8. (英) Fungal Proteins (日) (読) [継承]
9. (英) Genes, Reporter (日) (読) [継承]
10. (英) Genetic Vectors (日) (読) [継承]
11. (英) Green Fluorescent Proteins (日) (読) [継承]
12. (英) HeLa Cells (日) (読) [継承]
13. (英) Humans (日) (読) [継承]
14. (英) Leucine Zippers (日) (読) [継承]
15. (英) Luminescent Proteins (日) (読) [継承]
16. (英) Recombinant Fusion Proteins (日) (読) [継承]
17. (英) Repressor Proteins (日) (読) [継承]
18. (英) Saccharomyces cerevisiae (日) (読) [継承]
19. (英) Saccharomyces cerevisiae Proteins (日) (読) [継承]
20. (英) Transcription Factors (日) (読) [継承]
21. (英) Transcription, Genetic (日) (読) [継承]
22. (英) Transfection (日) (読) [継承]
23. (英) Tumor Cells, Cultured (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Biochemical and Biophysical Research Communications ([Elsevier])
(pISSN: 0006-291X, eISSN: 1090-2104)

ISSN (任意): 0006-291X
ISSN: 0006-291X (pISSN: 0006-291X, eISSN: 1090-2104)
Title: Biochemical and biophysical research communications
Title(ISO): Biochem. Biophys. Res. Commun.
Publisher: Elsevier Inc.
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 278 [継承]
(必須): 3 [継承]
(必須): 659 664 [継承]
都市 (任意):
年月日 (必須): 西暦 2000年 11月 30日 (平成 12年 11月 30日) [継承]
URL (任意):
DOI (任意): 10.1006/bbrc.2000.3840    (→Scopusで検索) [継承]
PMID (任意): 11095965    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意): 000165701900026 [継承]
Scopus (任意): 2-s2.0-0034735991 [継承]
評価値 (任意):
被引用数 (任意):
指導教員 (推奨):
備考 (任意): 1.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Satoshi Hino, Hitoshi Kawamata, Daisuke Uchida, Fumie Omotehara, Yoshihiro Miwa, Mila Nasima Begum, Hideo Yoshida and Mitsunobu Sato : Nuclear translocation of TSC-22 (TGF-beta-stimulated clone-22) concomitant with apoptosis: TSC-22 as a putative transcriptional regulator, Biochemical and Biophysical Research Communications, Vol.278, No.3, 659-664, 2000.
欧文冊子 ● Satoshi Hino, Hitoshi Kawamata, Daisuke Uchida, Fumie Omotehara, Yoshihiro Miwa, Mila Nasima Begum, Hideo Yoshida and Mitsunobu Sato : Nuclear translocation of TSC-22 (TGF-beta-stimulated clone-22) concomitant with apoptosis: TSC-22 as a putative transcriptional regulator, Biochemical and Biophysical Research Communications, Vol.278, No.3, 659-664, 2000.

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