『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=121836EID:121836, Map:0, LastModified:2015年7月21日(火) 13:51:57, Operator:[三木 ちひろ], Avail:TRUE, Censor:0, Owner:[北村 光夫], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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審査 (推奨): Peer Review [継承]
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組織 (推奨): 1.徳島大学.大学院ヘルスバイオサイエンス研究部.発達予防医歯学部門.病態予防医学講座 (2004年4月1日〜) [継承]
著者 (必須): 1.池原 敏孝 ([徳島文理大学])
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2.山口 久雄 ([徳島文理大学])
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3.細川 敬子
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4.芳地 一
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5.朴 基豪 (University of Medicine and Dentistry of New Jersey)
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6.水口 和生
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7. (英) Kashimoto Hideki (日) 樫本 英樹 (読) かしもとひでき
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8.北村 光夫 ([徳島大学.技術支援部])
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9.木内 陽介
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10.吉﨑 和男
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11.宮本 博司 ([徳島文理大学])
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題名 (必須): (英) Effects of a time-varying strong magnetic field on transient increase in Ca2+ release induced by cytosolic Ca2+ in cultured pheochromocytoma cells  (日)    [継承]
副題 (任意):
要約 (任意): (英) Exposure of pheochromocytoma (PC 12) cells to a time-varying 1.51 T magnetic field inhibited an increase in the intracellular Ca2+ concentration ([Ca2+]i) induced by addition of caffeine to Ca(2+)-free medium. This inhibition occurred after a 15-min exposure and was maintained for at least 2 h. [Ca2+]i sharply increased in cells loaded with cyclic ADP-ribose, and 2-h exposure significantly suppressed the increase. Addition of ATP induced a transient increase in intracellular Ca2+ release mediated by IP3 receptor, and this increase was strongly inhibited by the exposure. Results indicated that the magnetic field exposure strongly inhibited Ca2+ release mediated by both IP3 and ryanodine receptors in PC 12 cells. However, thapsigargin-induced Ca2+ influx (capacitative Ca2+ entry) across the cell membrane was unaffected. The ATP content was maintained at the normal level during the 2-h exposure, suggesting that ATP hydrolysis was unchanged. Therefore, Mg2+ which is known to be released by ATP hydrolysis and inhibit intracellular Ca2+ release may not relate the exposure-caused inhibition. Eddy currents induced in culture medium appear to change cell membrane properties and indirectly inhibit Ca2+ release from endoplasmic reticulum and other Ca2+ stores in PC 12 cells.  (日)    [継承]
キーワード (推奨): 1. (英) ryanodine receptor (日) (読) [継承]
2. (英) caffeine (日) (読) [継承]
3. (英) cyclic ADP-ribose (日) (読) [継承]
4. (英) time-varying magnetic field (日) (読) [継承]
5. (英) eddy current (日) (読) [継承]
発行所 (推奨): Elsevier Science [継承]
誌名 (必須): Biochimica et Biophysica Acta (BBA) - General Subjects ([Elsevier Science])
(pISSN: 0304-4165)

ISSN (任意): 0304-4165
ISSN: 0304-4165 (pISSN: 0304-4165, eISSN: 1872-8006)
Title: Biochimica et biophysica acta. General subjects
Title(ISO): Biochim Biophys Acta Gen Subj
Publisher: Elsevier BV
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 1724 [継承]
(必須): 1-2 [継承]
(必須): 8 16 [継承]
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年月日 (必須): 西暦 2005年 4月 2日 (平成 17年 4月 2日) [継承]
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DOI (任意): 10.1016/j.bbagen.2005.03.008    (→Scopusで検索) [継承]
PMID (任意): 15890451    (→Scopusで検索) [継承]
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WOS (任意): 000230182400002 [継承]
Scopus (任意): 2-s2.0-20444422530 [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Physiology, Pathophysiological Preventive Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Toshitaka Ikehara, Hisao Yamaguchi, Keiko Hosokawa, Hitoshi Houchi, Ki Ho Park, Kazuo Minakuchi, Hideki Kashimoto, Mitsuo Kitamura, Yohsuke Kinouchi, Kazuo Yoshizaki and Hiroshi Miyamoto : Effects of a time-varying strong magnetic field on transient increase in Ca2+ release induced by cytosolic Ca2+ in cultured pheochromocytoma cells, Biochimica et Biophysica Acta (BBA) - General Subjects, Vol.1724, No.1-2, 8-16, 2005.
欧文冊子 ● Toshitaka Ikehara, Hisao Yamaguchi, Keiko Hosokawa, Hitoshi Houchi, Ki Ho Park, Kazuo Minakuchi, Hideki Kashimoto, Mitsuo Kitamura, Yohsuke Kinouchi, Kazuo Yoshizaki and Hiroshi Miyamoto : Effects of a time-varying strong magnetic field on transient increase in Ca2+ release induced by cytosolic Ca2+ in cultured pheochromocytoma cells, Biochimica et Biophysica Acta (BBA) - General Subjects, Vol.1724, No.1-2, 8-16, 2005.

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