『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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登録内容 (EID=100667)

EID=100667EID:100667, Map:0, LastModified:2014年1月28日(火) 17:03:20, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[石川 康子], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.徳島大学.歯学部.歯学科 [継承]
著者 (必須): 1. (英) Inoue Noriko (日) 井上 紀子 (読) いのうえ のりこ
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2. (英) IIida Hirokazu (日) 飯田 博一 (読) いいだ ひろかず
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3. (英) Yuan zhenfang (日) 袁 振芳 (読) えん しんほう
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4.石川 康子
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5. (英) Ishida Hajime (日) 石田 甫 (読) いしだ はじめ
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[継承]
題名 (必須): (英) Age-related decreases in the response of aquaporin-5 to acetylcholine in rat parotid glands.  (日)    [継承]
副題 (任意):
要約 (任意): (英) The responsiveness of AQP5 to nervous stimuli was studied in the parotid tissues of senescent (2-year-old) and young adult (10-week-old) rats. The increasing ratio by acetylcholine of the amount of AQP5 in the apical plasma membrane (APM) was 3.6-fold in the tissues of young adult rats, but 1.8-fold in those of senescent rats. However, the increasing ratios by epinephrine of the amount of AQP5 in APM of young adult and senescent rats were 2.3-fold and 1.8-fold, respectively. The SNI-2011 induced a persistent increase in the amount of AQP5 in APM even in senescent rats. The changes in the responsiveness of AQP5 in the tissues to nervous stimuli during aging corresponded to nitric oxide synthase activity. These results suggest that the stimulatory effect of acetylchorine on the abundance of AQP5 in APM of the parotid cells was markedly reduced during aging and that SNI-2011 prove effective for treatment of age-related xerostomia.  (日)    [継承]
キーワード (推奨): 1.顎口腔機能 (stomatognathic function) [継承]
2.加齢変化 (aging patterrn) [継承]
3.情報伝達機構 (signal transduction) [継承]
4.神経伝達物質 (neurotransmitter) [継承]
5.カルシウム (calcium) [継承]
発行所 (推奨):
誌名 (必須): Journal of Dental Research ([国際歯科研究学会])
(pISSN: 0022-0345, eISSN: 1544-0591)

ISSN (任意): 0022-0345
ISSN: 0022-0345 (pISSN: 0022-0345, eISSN: 1544-0591)
Title: Journal of dental research
Title(ISO): J Dent Res
Publisher: SAGE Publications
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 82 [継承]
(必須): 6 [継承]
(必須): 476 480 [継承]
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年月日 (必須): 西暦 2003年 6月 1日 (平成 15年 6月 1日) [継承]
URL (任意): http://ci.nii.ac.jp/naid/10015634664/ [継承]
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NAID (任意): 10015634664 [継承]
WOS (任意): 000183066700014 [継承]
Scopus (任意): 2-s2.0-0038507596 [継承]
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標準的な表示

和文冊子 ● Noriko Inoue, Hirokazu IIida, zhenfang Yuan, Yasuko Ishikawa and Hajime Ishida : Age-related decreases in the response of aquaporin-5 to acetylcholine in rat parotid glands., Journal of Dental Research, Vol.82, No.6, 476-480, 2003.
欧文冊子 ● Noriko Inoue, Hirokazu IIida, zhenfang Yuan, Yasuko Ishikawa and Hajime Ishida : Age-related decreases in the response of aquaporin-5 to acetylcholine in rat parotid glands., Journal of Dental Research, Vol.82, No.6, 476-480, 2003.

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