| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○招待 (推奨): |
| ○審査 (推奨): |
| ○カテゴリ (推奨): |
| ○共著種別 (推奨): |
| ○学究種別 (推奨): |
| ○組織 (推奨): | 1. | 徳島大学.大学院ヘルスバイオサイエンス研究部.生体システム栄養科学部門.摂食機能制御学講座 (2004年4月1日〜2015年3月31日)
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| ○著者 (必須): | 1. | 石川 康子
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| 2. | (英) Takafumi Eguchi (日) 江口 貴文 (読) えぐち たかふみ
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| 3. | (英) Mariusz T. Skowronski (日) マリウス スコロンスキー (読) マリウス スコロンスキー
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| 4. | (英) Hajime Ishida (日) 石田 甫 (読) いしだ はじめ
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| ○題名 (必須): | □ | (英) Acetylcholine acts on M3 muscarinic receptors and induces the translocation of aquaporin5 water channel via cytosolic Ca2+ elevation in rat parotid glands. (日)
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| ○副題 (任意): |
| ○要約 (任意): | □ | (英) To evaluate the role of aquaporin5 (AQP5) in salivary secretion induced by cholinergic stimulation, the alteration of the distribution of AQP5 in rat parotid tissues induced by acetylcholine (ACh) was studied by immunobolt analysis. The treatment of the tissues with ACh within 1 min induced the translocation of AQP5 from intracellular membranes (ICM) to apical membranes (APM), but that for more than 5 min resulted in the converse translocation from APM to ICM. The ACh-induced increase in the amount of AQP5 in APM was inhibited by atropine, p-F-HHSiD and TMB-8, but not by methoctramine, staurosporine or H-7. The calcium ionophore A-23187 alone stimulated the translocation of AQP5 between APM and ICM. These results indicated that ACh acted on M3 muscarinic receptors and induced the translocation of AQP5 between ICM and APM, and that the cytosolic Ca2+ elevation by ACh may play a key role in this translocation in rat parotid glands. (日)
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| ○キーワード (推奨): | 1. | 顎口腔機能 (stomatognathic function)
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| 2. | 情報伝達機構 (signal transduction)
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| 3. | 神経伝達物質 (neurotransmitter)
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| 4. | カルシウム (calcium)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Biochemical and Biophysical Research Communications ([Elsevier])
(pISSN: 0006-291X, eISSN: 1090-2104)
| ○ISSN (任意): | □ | 0006-291X
ISSN: 0006-291X
(pISSN: 0006-291X, eISSN: 1090-2104) Title: Biochemical and biophysical research communicationsTitle(ISO): Biochem Biophys Res CommunPublisher: Elsevier B.V. (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 245
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| ○号 (必須): | □ | 3
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| ○頁 (必須): | □ | 835 840
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 1998年 4月 28日 (平成 10年 4月 28日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1006/bbrc.1998.8395 (→Scopusで検索)
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| ○PMID (任意): | □ | 9588201 (→Scopusで検索)
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| ○CRID (任意): |
| ○WOS (任意): | □ | 000073489500034
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| ○Scopus (任意): | □ | 2-s2.0-0032576886
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| ○評価値 (任意): |
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| ○指導教員 (推奨): |
| ○備考 (任意): | 1. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't (日)
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