『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
〔閲覧〕【著作】
--- テーブル「著作」（著作（著書，論文，レター，国際会議など））は研究業績にかかる著作（著書，論文，レター，国際会議など）を登録するテーブルです．
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抽出条件
| REF= |  荒木 勉
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登録情報の数
有効な情報: 369件 + 無効な情報: 10件 = 全ての情報: 379件
全ての有効な情報 (369件)
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抽出結果のリスト
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排列順: 項目表示: Seiichi Takano, Michiyasu Hirama, Tsutomu Araki and Kunio Ogasawara : A new entry into the synthesis of the nine-membered indole alkaloids related to cleavamine. A stereospecific synthesis of (dl)-4.alpha.-dihydrocleavamine and (dl)-quebrachamine via the thio-Claisen rearrangement, Journal of the American Chemical Society, Vol.98, No.22, 7084-7085, 1976..[著者] ... Yoshihiro Endo, Eiichi Fujihira, Tsutomu Araki and Susumu Tsurufuji : Glucocorticoid receptors in carrageenin-induced granuloma in rats: activation to dexamethasone-binding form by sulfhydryl compounds., Journal of Steroid Biochemistry, Vol.14, No.12, 1337-1345, 1981..[著者] ... 二宮 健二, 関戸 祥三郎, 荒木 勉 : Nitrosourea系制癌剤MCNUの各種制癌剤との併用効果, 癌と化学療法, Vol.11, No.6, 1315-1323, 1984年..[著者] ... 関戸 祥三郎, 二宮 健二, 荒木 勉, 上野 柾, 金原 美穂子 : Nitrosourea系制癌剤MCNUの経口投与に関する基礎的研究, 癌と化学療法, Vol.11, No.7, 1492-1500, 1984年..[著者] ... 小暮 久也, 荒木 勉 : 脳虚血とその代謝, 臨床雑誌 内科, Vol.60, (号), 845-850, 1987年(0月)..[著者] ... 荒木 勉, 西岡 浩一郎, 幸 敏志, 小暮 久也 : 脳循環障害, --- 虚血に対する脳保護物質 ---, 治療学, Vol.119, (号), 65-69, 1987年(0月)..[著者] ... 小暮 久也, 泉山 公明, 高野 充, 荒木 勉, 西岡 浩一郎, 小笠原 国郎 : 老人性痴呆症と脳機能改善薬(朝永正徳，斉藤洋 編集), --- 老人性痴呆の予防·治療開発へのアプローチー薬物の分類および作用機序— ---, シーエムシー社, 東京, 1988年(0月)..[著者] ... Kyuya Kogure, Junji Tanaka and Tsutomu Araki : The mechanism of ischemia-induced brain cell injury, Neurochemical Pathology, Vol.9, No.1-3, 145-170, July 1988..[著者] ... 関戸 祥三郎, 細野 仁一, 平塚 幸蔵, 荒木 勉, 岩崎 守男 : 新規抗悪性腫瘍剤MCNUの薬理学的研究, 日本薬理学雑誌, Vol.92, No.2, 69-96, 1988年..[著者] ... Koji Abe, Tsutomu Araki and Kyuya Kogure : Recovery from edema and of protein synthesis differs between the cortex and caudate following transient focal cerebral ischemia in rats, Journal of Neurochemistry, Vol.51, No.5, 1470-1476, 1988..[著者] ... 小暮 久也, 荒木 勉, 西岡 浩一郎 : 細胞膜脂肪合成促進剤の虚血性脳細胞壊死抑止作用, 日本臨牀, Vol.46, No.12, 2769-2777, 1988年12月..[著者] ... K Kogure, Tsutomu Araki, N Sakamoto and K Ogasawara : Cerebrovascular Diseases, --- Chapter 17 Molecular considerations in pharmacoprotective agents ---, Raven Press, New York, (month)1989..[著者] ... K Kogure, H Onodera, T Yasuda, Tsutomu Araki and K Nishioka : Cerebral ischemia and calcium, --- Roles of calsium-activated enzymic reactions in ischemia-induced neuronal injury. ---, Springer-Verlag, (都市), (month)1989..[著者] ... S Sekido, Tsutomu Araki and K Ninomiya : Development of resistance to and cross-resistance with Ranimustine in experimental leukemia, Pharmacometrics, Vol.37, No.2, 243-252, 1989..[著者] ... Hiroshi Onodera, Tsutomu Araki and Kyuya Kogure : Protein kinase C activity in the rat hippocampus after forebrain ischemia: autoradiographic analysis by [3H]phorbol 12,13-dibutyrate, Brain Research, Vol.481, No.1, 1-7, 1989..[著者] ... 加藤 宏之, 荒木 勉, 小暮 久也 : 選択的脆弱性を有する脳細胞の虚血性壊死について, 老年期痴呆, Vol.3, No.2, 65-70, 1989年4月..[著者] ... Tsutomu Araki and Kyuya Kogure : Prevention of delayed neuronal death in gerbil hippocampus by a novel vinca alkaloid derivative (vinconate), Molecular and Chemical Neuropathology, Vol.11, No.1, 33-43, 1989..[著者] ... Hiroshi Onodera, Tsutomu Araki and Kyuya Kogure : Excitatory amino acid binding sites in the rat hippocampus after transient forebrain ischemia, Journal of Cerebral Blood Flow and Metabolism, Vol.9, No.5, 623-628, 1989..[著者] ... Tsutomu Araki, K Kogure and K Izumiyama : Prevention of ischemic neuronal damage by α1-adrenoceptor agonist (methoxamine)., Acta Neurologica Scandinavica, Vol.80, No.5, 451-454, 1989..[著者] ... Tsutomu Araki, H Kato and K Kogure : Selective neuronal vulnerability following transient cerebral ischemia in the gerbil: distribution and time course, Acta Neurologica Scandinavica, Vol.80, No.6, 548-553, 1989..[著者] ... 荒木 勉, 加藤 宏之, 小暮 久也 : カルシウム拮抗剤, カレントテラピー, Vol.8, (号), 102-1065, 1990年(0月)..[著者] ... Tsutomu Araki, Kyuya Kogure and K Nishioka : Comparative neuroprotective effects of pentobarbital, vinpocetine, flunarizine and ifenprodil on ischemic neuronal damage in the gerbil hippocampus, Research in Experimental Medicine, Vol.190, No.1, 19-23, 1990..[著者] ... Tsutomu Araki, K Nishioka, S Yuki and Kyuya Kogure : Vinconate prevents ischemic neuronal damage in the rat hippocampus, Acta Neurologica Scandinavica, Vol.81, No.2, 173-176, 1990..[著者] ... Tsutomu Araki, Hiroyuki Kato, T Inoue and Kyuya Kogure : Regional impairment of protein synthesis following brief cerebral ischemia in the gerbil, Acta Neuropathologica, Vol.79, No.5, 501-505, 1990..[著者] ... Hiroyuki Kato, Tsutomu Araki and Kyuya Kogure : Role of the excitotoxic mechanism in the development of neuronal damage following repeated brief cerebral ischemia in the gerbil: protective effects of MK-801 and pentobarbital, Brain Research, Vol.516, No.1, 175-179, 1990..[著者] ... Tsutomu Araki, Teruyoshi Inoue, Hiroyuki Kato, Kyuya Kogure and Matsutaro Murakami : Neuronal damage and calcium accumulation following transient cerebral ischemia in the rat, Molecular and Chemical Neuropathology, Vol.12, No.3, 203-213, 1990..[著者] ... Hiroyuki Kato, Tsutomu Araki, Kyuya Kogure, Matsutaro Murakami and Kazuo Uemura : Sequential cerebral blood flow changes in short-term cerebral ischemia in gerbils, Stroke, Vol.21, No.9, 1346-1349, 1990..[著者] ... Tsutomu Araki, Hiroyuki Kato and Kyuya Kogure : Neuronal damage and calcium accumulation following repeated brief cerebral ischemia in the gerbil, Brain Research, Vol.528, No.1, 114-122, 1990..[著者] ... Tsutomu Araki, Hiroyuki Kato, Kyuya Kogure and Teruyoshi Inoue : Regional neuroprotective effects of pentobarbital on ischemia-induced brain damage, Brain Research Bulletin, Vol.25, No.6, 861-865, 1990..[著者] ... 加藤 宏之, 荒木 勉, 小暮 久也 : 虚血性脳障害に対するいわゆる脳保護物質と脳保護薬について, 老年精神医学雑誌, Vol.2, (号), 824-831, 1991年(0月)..[著者] ... Hideaki Hara, Hiroyuki Kato, Tsutomu Araki, Hiroshi Onodera and Kyuya Kogure : Involvement of lipid peroxidation and inhibitory mechanisms on ischemic neuronal damage in gerbil hippocampus: Quantitative autoradiographic studies on second messenger and neurotransmitter systems, Neuroscience, Vol.42, No.1, 159-169, 1991..[著者] ... Haruo Nagasawa, Tsutomu Araki and Kyuya Kogure : Alteration of 45Ca accumulation and second messenger system in the post-ischemc rat brain using [3H]inositol 1,4,5-trisphosphate autoradiography, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1991, (号), 142-150, 1991..[著者] ... Hiroyuki Kato, Tsutomu Araki, Hideaki Hara and Kyuya Kogure : Alterations in neurotransmitter-receptor and second-messenger system binding in the gerbil hippocampus following repeated ischemic insults, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1991, (号), 151-159, 1991..[著者] ... Haruo Nagasawa, Tsutomu Araki and Kyuya Kogure : Alteration of [3H]forskolin binding in the postischemic rat brain, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1991, (号), 160-166, 1991..[著者] ... Haruo Nagasawa, Tsutomu Araki and Kyuya Kogure : Alteration of dopamine D-1 receptor in the postischemic rat brain, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1991, (号), 167-171, 1991..[著者] ... Tsutomu Araki, Hiroyuki Kato and Kyuya Kogure : Comparative protective effects of vinconate, baclofen, and pentobarbital against neuronal damage following repeated brief cerebral ischemia in the gerbil brain, Research in Experimental Medicine, Vol.191, No.6, 371-378, 1991..[著者] ... Tsutomu Araki, Kyuya Kogure and M Murakami : Prevention of abnormal calcium accumulation in postischemic gerbil brain by vinconate, Acta Neurologica Scandinavica, Vol.83, No.3, 155-160, 1991..[著者] ... Tsutomu Araki, Hiroyuki Kato, T Inoue and Kyuya Kogure : Long-term observations on calcium accumulation in postischemic gerbil brain, Acta Neurologica Scandinavica, Vol.83, No.4, 244-249, 1991..[著者] ... Hideaki Hara, Hiroshi Onodera, Hiroyuki Kato, Tsutomu Araki and Kyuya Kogure : Autoradiographic analysis of second messenger and neurotransmitter system receptors in the gerbil hippocampus following transient forebrain ischemia, Brain Research, Vol.545, No.1-2, 87-96, 1991..[著者] ... Tsutomu Araki, Hiroyuki Kato, HIdeaki Hara and Kyuya Kogure : Postischemic alteration of [3H]forskolin binding sites in selectively vulnerable areas: an autoradiographic study of gerbil brain, Neuroscience Letters, Vol.125, No.2, 159-162, 1991..[著者] ... Hiroyuki Kato, Tsutomu Araki and Kyuya Kogure : Postischemic spontaneous hyperthermia is not a major aggravating factor for neuronal damage following repeated brief cerebral ischemia in the gerbil, Neuroscience Letters, Vol.126, No.1, 21-24, 1991..[著者] ... Hiroyuki Kato, Tsutomu Araki, Hideaki Hara and Kyuya Kogure : Sequential changes in muscarinic acetylcholine, adenosine A1 and calcium antagonist binding sites in the gerbil hippocampus following repeated brief ischemia, Brain Research, Vol.553, No.1, 33-38, 1991..[著者] ... Hiroyuki Kato, Yong Liu, Tsutomu Araki and Kyuya Kogure : Temporal profile of the effects of pretreatment with brief cerebral ischemia on the neuronal damage following secondary ischemic insult in the gerbil: cumulative damage and protective effects, Brain Research, Vol.553, No.2, 238-242, 1991..[著者] ... Tsutomu Araki, Hiroyuki Kato and Kyuya Kogure : Alteration of second messenger systems after transient cerebral ischemia in gerbils: Protective effect of pentobarbital and an autoradiographic analysis, Neuroscience Letters, Vol.130, No.1, 57-60, 1991..[著者] ... Tsutomu Araki, Hiroyuki Kato, Kyuya Kogure and Takashi Saito : Postischemic alteration of muscarinic acetylcholine, adenosine A1 and calcium antagonist binding sites in selectively vulnerable areas: An autoradiographic study of gerbil brain, Journal of the Neurological Sciences, Vol.106, No.2, 206-212, 1991..[著者] ... Hiroyuki Kato, Tsutomu Araki, Hideaki Hara and Kyuya Kogure : Autoradiographic analysis of second-messenger systems in the gerbil hippocampus following repeated brief ischemic insults, Brain Research Bulletin, Vol.27, No.6, 759-765, 1991..[著者] ... K Abe, Tsutomu Araki, J Kawagoe, M Aoki and Kyuya Kogure : Phospholipid metabolism and second messenger system after brain ischemia, Advances in Experimental Medicine and Biology, Vol.318, 183-195, 1992..[著者] ... Tsutomu Araki, Yasuo Kanai, Kyuya Kogure and Yukiharu Ishida : Age-related alterations in second-messenger systems in the gerbil brain: autoradiographic analysis and effect of vinconate, Research in Experimental Medicine, Vol.194, No.4, 221-230, 1992..[著者] ... 劉 勇, 加藤 宏之, 中田 直樹, 村瀬 健史, 田中 留美子, 荒木 勉, 小暮 久也 : 短時間の脳虚血の前処置によってラット脳に虚血耐性を獲得させる研究, 第14回東北脳血管障害懇話会学術記録集, 83-87, 1992年..[著者] ... Haruo Nagasawa, Tsutomu Araki and Kyuya Kogure : Autoradiographic analysis of protein kinase C activity in the postischemic rat brain using, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1992, 144-151, 1992..[著者] ... Haruo Nagasawa, Tsutomu Araki and Kyuya Kogure : Alteration of cyclic adenosine monophosphate phosphodiesterase in the postischemic rat brain using [3H]rolipram autoradiography, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1992, 152-157, 1992..[著者] ... Tsutomu Araki, Hiroyuki Kato and Kyuya Kogure : Protective effect of vinconate, a novel vinca alkaloid derivative, on glucose utilization and brain edema in a new rat model of middle cerebral artery occlusion, General Pharmacology: The Vascular System, Vol.23, No.1, 141-146, 1992..[著者] ... Tsutomu Araki, Hiroyuki Kato and Kyuya Kogure : Protective effect of a novel vinca alkaloid derivative, vinconate, against alterations in binding sites of second messengers after transient cerebral ischemia in gerbils, General Pharmacology: The Vascular System, Vol.23, No.1, 115-121, 1992..[著者] ... Tsutomu Araki, Hiroyuki Kato and Kyuya Kogure : Postischemic alteration of muscarinic acetylcholine and adenosine A1 binding sites in gerbil brain. Protective effects of a novel vinca alkaloid derivative, vinconate, and pentobarbital using an autoradiographic study, Research in Experimental Medicine, Vol.192, No.2, 79-78, 1992..[著者] ... Haruo Nagasawa, Tsutomu Araki and Kyuya Kogure : Alteration of dopamine D1 receptor in the strionigral system of the postischemic rat brain, Neuroscience Letters, Vol.134, No.2, 271-274, 1992..[著者] ... Tsutomu Araki, Hiroyuki Kato, Hideaki Hara and Kyuya Kogure : Postischemic binding of [3H]phorbol 12,13-dibutyrate and [3H]inositol 1,4,5-trisphosphate in the gerbil brain: An autoradiographic study, Neuroscience, Vol.46, No.4, 973-980, 1992..[著者] ... Tsutomu Araki, Hiroyuki Kato, Kyuya Kogure, Katsuro Shuto and Yukiharu Ishida : Autoradiographic mapping of neurotransmitter system receptors in mammalian brain, Pharmacology, Biochemistry, and Behavior, Vol.41, No.3, 539-542, 1992..[著者] ... Teruyoshi Inoue, Hiroyuki Kato, Tsutomu Araki and Kyuya Kogure : Emphasized selective vulnerability after repeated nonlethal cerebral ischemic insults in rats, Stroke, Vol.23, No.5, 739-745, 1992..[著者] ... Hiroyuki Kato, Young Liu, Tsutomu Araki and Kyuya Kogure : MK-801, but not anisomycin, inhibits the induction of tolerance to ischemia in the gerbil hippocampus, Neuroscience Letters, Vol.139, No.1, 118-121, 1992..[著者] ... Tsutomu Araki, Hiroyuki Kato and Kyuya Kogure : Mapping of second messenger and rolipram receptors in mammalian brain, Brain Research Bulletin, Vol.28, No.6, 843-848, 1992..[著者] ... Hiroyuki Kato, Tsutomu Araki and Kyuya Kogure : Preserved neurotransmitter receptor binding following ischemia in preconditioned gerbil brain, Brain Research Bulletin, Vol.29, No.3-4, 395-400, 1992..[著者] ... Haruo Nagasawa, Tsutomu Araki and Kyuya Kogure : Autoradiographic analysis of cyclic adenosine monophosphate phosphodiesterase using [3H]rolipram in the postischemic rat brain, Neuroscience Letters, Vol.144, No.1-2, 34-37, 1992..[著者] ... Tsutomu Araki, Hiroyuki Kato, Kyuya Kogure and Yasuo Kanai : Long-term changes in gerbil brain neurotransmitter receptors following transient, British Journal of Pharmacology, Vol.107, No.2, 437-442, 1992..[著者] ... Haruo Nagasawa, Tsutomu Araki and Kyuya Kogure : Autoradiographic analysis of second messenger and neurotransmitter receptor bindings in the strionigral system of the postischemic rat brain, Journal of Neuroscience Research, Vol.33, No.3, 485-492, 1992..[著者] ... Tsutomu Araki, Fumie Murakami, Yasuo Kanai, Hiroyuki Kato and Kyuya Kogure : Autoradiographic analysis of dopamine D1 receptors in the gerbil brain following transient cerebral ischemia, General Pharmacology: The Vascular System, Vol.23, No.6, 1073-1078, 1992..[著者] ... Hiroyuki Kato, Tsutomu Araki, Kenshi Murase and Kyuya Kogure : Induction of tolerance to ischemia: Alterations in second-messenger systems in the gerbil hippocampus, Brain Research Bulletin, Vol.29, No.5, 559-565, 1992..[著者] ... Hiroyuki Kato, Tsutomu Araki and Kyuya Kogure : Repeated focal cerebral ischemia in gerbils is associated with development of infarction, Brain Research, Vol.596, No.1-2, 315-319, 1992..[著者] ... K Abe, J Kawagoe, Tsutomu Araki, M Aoki and Kyuya Kogure : Differential expression of heat shock protein 70 gene between the cortex and caudate after transient focal cerebral ischaemia in rats, Neurological Research, Vol.14, No.5, 381-385, 1992..[著者] ... Tsutomu Araki, Yasuo Kanai, Hiroyuki Kato and Kyuya Kogure : Sequential alteration of [3H]rolipram binding in gerbil brain after transient cerebral ischemia, Brain Research Bulletin, Vol.31, No.1-2, 85-89, 1993..[著者] ... Tsutomu Araki, Yasuo Kanai, Fumie Murakami, Hiroyuki Kato and Kyuya Kogure : Changes of [3H]cyclic adenosine monophosphate binding in the gerbil brain following transient cerebral ischemia: an autoradiographic study and investigation of the effects of vinconate and pentobarbital, Research in Experimental Medicine, Vol.193, No.1, 57-64, 1993..[著者] ... 劉 勇, 加藤 宏之, 中田 直樹, 村瀬 健史, 劉 暁宏, 陳 停, 田中 留美子, 荒木 勉, 小暮 久也 : ラット海馬における虚血耐性の獲得と熱ショック蛋白70の役割, Brain Hypoxia研究会講演集, Vol.7, (号), 37-41, 1993年..[著者] ... Hiroyuki Kato, Tsutomu Araki, Kenshi Murase and Kyuya Kogure : Alteration of [3H]cyclic AMP and [3H]rolipram binding in the gerbil hippocampus following repeated ischemic insults, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1993, 109-113, 1993..[著者] ... Hiroyuki Kato, Tsutomu Araki and Kyuya Kogure : Alterations in [3H]MK-801 and [3H]muscimol binding in the gerbil hippocampus following repeated ischemic insults, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1993, 114-118, 1993..[著者] ... Hiroyuki Kato, N Nagasawa, Tsutomu Araki, Yasuto Itoyama and Kyuya Kogure : Facilitated recovery of protein synthase following ischemia in the brain with induced ischemic tolerance, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1993, (号), 119-122, 1993..[著者] ... Tsutomu Araki, Hiroyuki Kato, Haruo Nagasawa, Kyuya Kogure and Yasuto Itoyama : Postischemic changes of spirodecanone binding in the gerbil hippocampus, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1993, 123-129, 1993..[著者] ... H Hasegawa, Tsutomu Araki and Kyuya Kogure : Alterations of second messenger and neurotransmitter receptor systems in the exo-focal postischemic brain areas of the rat: in vitro autoradiography, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1993, 130-139, 1993..[著者] ... Hiroyuki Kato, Tsutomu Araki, Kenshi Murase and Kyuya Kogure : Alterations in [3H]MK-801, [3H]muscimol, [3H]cyclic AMP, and [3H]rolipram binding in the gerbil hippocampus following repeated ischemic insults, Neuroscience, Vol.52, No.2, 245-253, 1993..[著者] ... Fumie Murakami, Tsutomu Araki, Yasuo Kanai, Hiroyuki Kato and Kyuya Kogure : Neuroprotective effect of vinconate against postischemic alterations in binding of [3H]SCH 23390 in the gerbil brain, General Pharmacology: The Vascular System, Vol.24, No.1, 23-28, 1993..[著者] ... Tsutomu Araki, Yasuo Kanai, Hiroyuki Kato, Kyuya Kogure, Katsuro Shuto and Yukiharu Ishida : Effect of vinconate against regional age-related changes in the gerbil brain, Pharmacology, Biochemistry, and Behavior, Vol.44, No.1, 17-25, 1993..[著者] ... Kenshi Murase, Hiroyuki Kato, Tsutomu Araki and Kyuya Kogure : Sequential alterations of [3H]rolipram and [3H]cyclic adenosine monophosphate binding in the gerbil brain following transient cerebral ischemia, Brain Research, Vol.602, No.2, 234-239, 1993..[著者] ... Tsutomu Araki, Hiroyuki Kato, Yasuo Kanai and Kyuya Kogure : Postischemic changes of intracellular second messengers in the gerbil brain after long-term survival: An autoradiographic study, Neuroscience, Vol.53, No.3, 829-836, 1993..[著者] ... K Abe, J Kawagoe, Tsutomu Araki, M Aoki, K Sugimoto and Kyuya Kogure : Differential expression of heat shock protein 70 gene between the cortex and caudate after transient focal ischemia in rats, XVIth International Symposium on Cerebral Blood Flow and Metabolism, Sendai, May 1993..[著者] ... Hiroyuki Kato, Tsutomu Araki, T Chen, N Nakata and Kyuya Kogure : Long-term changes in the gerbil brain following repeated sublethal ischemic insults, XVIth International Symposium on Cerebral Blood Flow and Metabolism, Sendai, May 1993..[著者] ... Haruo Nagasawa, Tsutomu Araki and Kyuya Kogure : Alteration of protein kinase C activity in the postischemic rat brain areas using in vitro [3H]phorbol 12,13-dibutyrate autoradiography, Journal of Neural Transmission, Vol.92, No.2-3, 107-115, 1993..[著者] ... Tsutomu Araki, Hiroyuki Kato, Yasuo Kanai and Kyuya Kogure : Sequential changes of [3H]cyclic AMP binding in the gerbil brain following transient cerebral ischaemia, The Journal of Pharmacy and Pharmacology, Vol.45, No.7, 674-677, 1993..[著者] ... Tsutomu Araki, Yasuo Kanai, Fumie Murakami, Hiroyuki Kato and Kyuya Kogure : Postischemic changes in the binding of excitatory and inhibitory neurotransmitters in the gerbil brain, Pharmacology, Biochemistry, and Behavior, Vol.45, No.4, 945-949, 1993..[著者] ... Yasuo Kanai, Tsutomu Araki, Fumie Murakami, Hiroyuki Kato and Kyuya Kogure : Effect of pentobarbital on postischemic SCH 23390 and rolipram binding in gerbil brain, European Journal of Pharmacology, Vol.248, No.2, 191-198, 1993..[著者] ... Fumie Murakami, Tsutomu Araki, Yasuo Kanai and Kyuya Kogure : Effect of vinconate against alterations in [3H]naloxone, [3H]MK-801 and [3H]muscimol bindings after transient cerebral ischemia in gerbils, Archives Internationales de Pharmacodynamie et de Therapie, Vol.325, 21-34, 1993..[著者] ... Tsutomu Araki, Hiroyuki Kato, Yasuo Kanai and Kyuya Kogure : Long-term observations in gerbil brain following transient cerebral ischemia: Autoradiographic and histological study, Metabolic Brain Disease, Vol.8, No.3, 181-195, 1993..[著者] ... Shigemasa Kinbara, Kaoru Ishizaki, Yoshishige Takeuchi, Norio Miyazawa and Tsutomu Araki : Protection against alpha-naphthylisothiocyanate-induced acute cholestasis in mice by a novel taurine conjugate of ursodeoxycholate (UR-906), The Japanese Journal of Pharmacology, Vol.63, No.1, 125-127, 1993..[著者] ... Tsutomu Araki, Fumie Murakami, Yasuo Kanai, Hiroyuki Kato and Kyuya Kogure : Changes of spirodecanone binding in the gerbil hippocampus after cerebral ischaemia, NeuroReport, Vol.25, No.1, 37-40, 1993..[著者] ... Tsutomu Araki, Fumie Murakami, Yasuo Kanai, Hiroyuki Kato and Kyuya Kogure : Naloxone receptor binding in gerbil striatum and hippocampus following transient cerebral ischemia, Neurochemistry International, Vol.23, No.4, 319-325, 1993..[著者] ... Tsutomu Araki, Hiroyuki Kato, Yasuo Kanai and Kyuya Kogure : Selective changes of neurotransmitter receptors in middle-aged gerbil brain, Neurochemistry International, Vol.23, No.6, 541-548, 1993..[著者] ... 加藤 宏之, 荒木 勉, 小暮 久也 : 脳虚血とエネルギー代謝障害, TOKYO TANABE QUARTERLY, Vol.40, (号), 4-13, 1994年(0月)..[著者] ... Hiroyuki Kato, Tsutomu Araki, Hideaki Hara and Kyuya Kogure : Regional changes in [3H]inositol 1,4,5-triphosphate binding in the gerbil brain following repeated sublethal ischemia, Brain Research Bulletin, Vol.33, No.4, 465-468, 1994..[著者] ... Haruo Nagasawa, Tsutomu Araki and Kyuya Kogure : Autoradiographic analysis of second-messenger and neurotransmitter receptor systems in the exo-focal remote areas of postischemic rat brain, Brain Research Bulletin, Vol.35, No.4, 347-352, 1994..[著者] ... H Hasegawa, Tsutomu Araki and Yasuto Itoyama : Autoradiographic analysis of muscarinic acetylcholine binding sites in the exo-focal remote areas of the postischemic rat brain, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1994, 119-125, 1994..[著者] ... Hiroyuki Kato, Ting Chen, Tsutomu Araki, Kyuya Kogure and Yasuto Itoyama : Effects of a cyclic AMP-selective phosphodiesterase inhibitor, rolipram, on age-related changes in neurotransmission and transduction systems in the rat brain, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1994, 128-133, 1994..[著者] ... Hiroyuki Kato, Tsutomu Araki, Ting Chen, Xiao-Hong Liu, Kyuya Kogure and Yasuto Itoyama : Effects of a cyclic AMP-selective phosphodiesterase inhibitor, rolipram, on age-related changes in the rat brain, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1994, 128-133, 1994..[著者] ... Tsutomu Araki, Hiroyuki Kato, Yasuto Itoyama, Takehiko Fujiwara and Yasuto Itoyama : Changes of [3H]hemicholinium-3 binding in the postischemic gerbil brain, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1994, 139-144, 1994..[著者] ... Tsutomu Araki, Hiroyuki Kato, Takehiko Fujiwara and Yasuto Itoyama : Alterations of dopamine rgic receptors in the gerbil striatum after transient cerebral ischemia, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1994, (号), 159-170, 1994..[著者] ... Haruo Nagasawa, Tsutomu Araki and Yasuto Itoyama : Multi-focal disturbances of the postischemic rat brain by measuring blood flow, glucose metabolism and adenosine A1 binding activity, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1994, 159-170, 1994..[著者] ... Haruo Nagasawa, Tsutomu Araki and Kyuya Kogure : Alteration of muscarinic acetylcholine binding sites in the postischemic brain areas of the rat using in vitro autoradiography, Journal of the Neurological Sciences, Vol.121, No.1, 27-31, 1994..[著者] ... Hideaki Fujikura, Hiroyuki Kato, Tsutomu Araki, Hideaki Ban, Yoshinari Hasegawa and Kyuya Kogure : Effects of naftidrofuryl oxalate, a 5-HT2 antagonist, on neuronal damage and local cerebral blood flow following transient cerebral ischemia in gerbils, Brain Research, Vol.646, No.1, 103-106, 1994..[著者] ... Xiao-Hong Liu, Hiroyuki Kato, Tsutomu Araki, Yasuto Itoyama, Kanefusa Kato and Kyuya Kogure : An immunohistochemical study of copper/zinc superoxide dismutase and manganese superoxide dismutase following focal cerebral ischemia in the rat, Brain Research, Vol.644, No.2, 257-266, 1994..[著者] ... Xiao-Hong Liu, Hiroyuki Kato, Tsutomu Araki, Yasuo Itoyama, Kanefusa Kato and Kyuya Kogure : An immunohistochemical observation of manganese superoxide dismutase in rat substantia nigra after occlusion of middle cerebral artery, Neuroscience Letters, Vol.173, No.1-2, 103-106, 1994..[著者] ... Hideaki Ban, Hiroyuki Kato, Tsutomu Araki, Hideaki Fujikura, Yoshinari Hasegawa and Kyuya Kogure : Effects of naftidrofuryl oxalate, a 5HT2 antagonist, on neurotransmission and transduction systems in the gerbil hippocampus, Brain Research, Vol.646, No.2, 211-216, 1994..[著者] ... Tsutomu Araki, Hiroyuki Kato, Yasuo Kanai and Kyuya Kogure : Age-dependent changes in second messenger and rolipram receptor systems in the gerbil brain, Journal of Neural Transmission, Vol.97, No.2, 135-147, 1994..[著者] ... Ken Arita, Tsutomu Araki, Katsuro Shuto and Masamichi Satoh : Effect of vinconate on long-term potentiation in a mossy fiber-CA3 system of guinea pig hippocampal slices, Biological & Pharmaceutical Bulletin, Vol.17, No.7, 987-989, 1994..[著者] ... Tsutomu Araki, Hiroyuki Kato, Xiao-Hong Liu, Yasuo Itoyama, Kyuya Kogure and Kanefusa Kato : Delayed damage of striatal interneurons after cerebral ischemia in the gerbil, Neuroscience Letters, Vol.176, No.1, 17-20, 1994..[著者] ... Haruo Nagasawa, Tsutomu Araki and Kyuya Kogure : Alteration of adenosine A1 receptor binding in the post-ischaemic rat brain, NeuroReport, Vol.5, No.12, 1453-1456, 1994..[著者] ... Hiroyuki Kato, Kyuya Kogure, Yong Liu, Tsutomu Araki and Yasuto Itoyama : nduction of NADPH-diaphorase activity in the hippocampus in a rat model of cerebral ischemia and ischemic tolerance, Brain Research, Vol.652, No.1, 71-75, 1994..[著者] ... Ting Chen, Hiroyuki Kato, Xiao-Hong Liu, Tsutomu Araki, Yasuto Itoyama and Kyuya Kogure : Ischemic tolerance can be induced repeatedly in the gerbil hippocampal neurons, Neuroscience Letters, Vol.177, No.1-2, 159-161, 1994..[著者] ... Tsutomu Araki, Hiroyuki Kato, Xiao-Hong Liu, Kyuya Kogure, Kanefusa Kato and Yasuto Itoyama : An immunohistochemical study of parvalbumin containing interneurons in the gerbil hippocampus after cerebral ischemia, Metabolic Brain Disease, Vol.9, No.3, 225-234, 1994..[著者] ... Yasuo Kanai, Tsutomu Araki, Hiroyuki Kato and Kyuya Kogure : Effect of pentobarbital on postischemic MK-801, muscimol, and naloxone bindings in the gerbil brain, Brain Research, Vol.657, No.1-2, 51-58, 1994..[著者] ... Hiryoyuki Kato, Xiao-Hong Liu, Tsutomu Araki and Yasuto Itoyama : Bromocriptine protects against hippocampal neuronal damage following cerebral ischemia in the gerbil, International Academy of Biomedical and Drug Research, Tokyo, Oct. 1994..[著者] ... Fumie Murakami, Tsutomu Araki, Yasuo Kanai, Hiroyuki Kato, Takehiko Fujiwara and Kyuya Kogure : Effects of vinconate and pentobarbital against postischemic alterations in spirodecanone binding sites in the gerbil brain, Pharmacology, Vol.49, No.5, 286-295, 1994..[著者] ... Yasuo Kanai, Tsutomu Araki, Hiroyuki Kato and Kyuya Kogure : Autoradiographic distribution of neurotransmitter and second messenger system receptors in animal brains, Behavioural Brain Research, Vol.65, No.1, 67-73, 1994..[著者] ... Hiroyuki Kato, Kyuya Kogure, Tsutomu Araki and Yasuto Itoyama : Astroglial and microglial reactions in the gerbil hippocampus with induced ischemic tolerance, Brain Research, Vol.664, No.1-2, 69-76, 1994..[著者] ... Eun Joo Lee, Hiroyuki Kato, Tsutomu Araki, Tsong-Hai Lee, Choon Sang Bae, Jae Kwon Choi and Yasuto Itoyama : Ontogeny of protein kinase C in the rat hippocampus: an autoradiographic study with [3H]phorbol 12,13-dibutyrate, Brain Research, Vol.665, No.1, 127-129, 1994..[著者] ... Tsutomu Araki, Hiroyuki Kato, Xia-Hong Liu, Kyuya Kogure and Yasuo Itoyama : Induction of heat shock protein 70 and glial fibrillary acidic protein in the postischemic gerbil hippocampus, Metabolic Brain Disease, Vol.9, No.4, 369-375, 1994..[著者] ... Hiroyuki Kato, Tsutomu Araki, Yasuto Itoyama and Kyuya Kogure : Calcium deposits in the thalamus following repeated cerebral ischemia and long-term survival in the gerbil, Brain Research Bulletin, Vol.38, No.1, 25-30, 1995..[著者] ... Hiroyuki Kato, Kyuya Kogure, Naoki Nakata, Tsutomu Araki and Yasuto Itoyama : Facilitated recovery from postischemic suppression of protein synthesis in the gerbil brain with ischemic tolerance, Brain Research Bulletin, Vol.36, No.2, 205-208, 1995..[著者] ... 加藤 宏之, 荒木 勉, 陳 停, 李 宗海, 糸山 泰人, 小暮 久也 : 虚血性神経細胞障害とニューロンーグリア相互作用, 第17回東北脳血管障害懇話会学術記録集, 49-53, 1995年..[著者] ... Tsutomu Araki, Hiroyuki Kato, Haruo Nagasawa and Yasuto Itoyama : Effect of aging in bindings of second messengers in the rat brain, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1995, 118-124, 1995..[著者] ... Hiroyuki Kato, Kyuya Kogure, Tsutomu Araki, Xiao-Hong Liu, Kanefusa Kato and Yasuto Itoyama : Immunohistochemical localization of superoxide dismutase in the hippocampus following ischemia in a gerbil model of ischemic tolerance, Journal of Cerebral Blood Flow and Metabolism, Vol.15, No.1, 60-70, 1995..[著者] ... Hiroyuki Kato, Tsutomu Araki, Yasuto Itoyama and Kyuya Kogure : Rolipram, a cyclic AMP-selective phosphodiesterase inhibitor, reduces neuronal damage following cerebral ischemia in the gerbil, European Journal of Pharmacology, Vol.272, No.1, 107-110, 1995..[著者] ... Tsutomu Araki, Hiroyuki Kato, T Fujiwara, Kyuya Kogure and Yasuto Itoyama : Alteration of [3H]hemicholinium-3 binding in the post-ischaemic gerbil brain, NeuroReport, Vol.6, No.3, 561-564, 1995..[著者] ... Hiroyuki Kato, Kyuya Kogure, Tsutomu Araki and Yasuto Itoyama : Induction of Jun-like immunoreactivity in astrocytes in gerbil hippocampus with ischemic tolerance, Neuroscience Letters, Vol.189, No.1, 13-16, 1995..[著者] ... Hiroyuki Kato, Kyuya Kogure, Xiao-Hong Liu, Tsutomu Araki, Kanefusa Kato and Yasuto Itoyama : Immunohistochemical localization of the low molecular weight stress protein HSP27 following focal cerebral ischemia in the rat, Brain Research, Vol.679, No.1, 1-7, 1995..[著者] ... Tsutomu Araki, Hiroyuki Kato, Takehiko Fujiwara, Kyuya Kogure and Yasuto Itoyama : Post-ischemic changes of [3H]glycine binding in the gerbil brain after cerebral ischemia, European Journal of Pharmacology, Vol.278, No.2, 91-96, 1995..[著者] ... Hiroyuki Kato, Xiao-Hong Liu, Tsutomu Araki and Yasuto Itoyama : Immunohistochemical localaization of a small heat shock protein HSP 27 following focal cerebral ischemia in the rat, The 17 International Symposium on Cerebral Blood Flow and Metabolism(Brain'95), Cologne, Germany, July 1995..[著者] ... Hiroyuki Kato, Tsutomu Araki, Yasuto Itoyama, Kyuya Kogure and Kanefusa Kato : An immunohistochemical study of heat shock protein-27 in the hippocampus in a gerbil model of cerebral ischemia and ischemic tolerance, Neuroscience, Vol.68, No.1, 65-71, 1995..[著者] ... Hiroyuki Kato, Kyuya Kogure, Tsutomu Araki and Yasuto Itoyama : Graded expression of immunomolecules on activated microglia in the hippocampus following ischemia in a rat model of ischemic tolerance, Brain Research, Vol.694, No.1-2, 85-93, 1995..[著者] ... Tsutomu Araki, Hiroyuki Kato, Takehiko Fujiwara and Yasuto Itoyama : Age-related changes in bindings of second messengers in the rat brain, Brain Research, Vol.704, No.2, 227-232, 1995..[著者] ... Tsutomu Araki, Hiroyuki Kato, Katsuro Shuto, Takehiko Fujiwara and Yasuto Itoyama : Effect of nitric oxide synthase inhibitor on age-related changes in second messenger systems and calcium channels in rats, Metabolic Brain Disease, Vol.12, No.1, 83-92, 1996..[著者] ... Tsutomu Araki, Hiroyuki Kato, Katsuro Shuto, Takehiko Fujiwara and Yasuto Itoyama : Different age-related changes in NMDA and glycine receptors in the rat brain, Environmental Toxicology and Pharmacology, Vol.1, No.2, 103-107, 1996..[著者] ... Tsutomu Araki, Hiroyuki Kato, Takehiko Fujiwara and Yasuto Itoyama : Regional age-related alterations in cholinergic and GABAergic receptors in the rat brain, Mechanisms of Ageing and Development, Vol.88, No.1-2, 49-60, 1996..[著者] ... Tsutomu Araki, Hiroyuki Kato, Katsuro Shuto, Takehiko Fujiwara, Kyuya Kogure and Yasuto Itoyama : Effects of cerebral ischemia on dopamine receptors in the gerbil striatum, European Journal of Pharmacology, Vol.306, No.1-3, 73-79, 1996..[著者] ... Hiroyuki Kato, Kyuya Kogure, Xiao-Hong Liu, Tsutomu Araki and Yasuto Itoyama : Progressive expression of immunomolecules on activated microglia and invading leukocytes following focal cerebral ischemia in the rat, Brain Research, Vol.734, No.1-2, 203-212, 1996..[著者] ... Tsutomu Araki, Hiroyuki Kato, Katsuro Shuto, Takehiko Fujiwara and Yasuto Itoyama : Effects of vinconate on neurotransmitter receptor systems in aged rat brain, Environmental Toxicology and Pharmacology, Vol.2, No.4, 343-349, 1996..[著者] ... Tsuneyasu Kobayashi, Tsutomu Araki, Yasuto Itoyama, Tomihisa Ohta and Yoshiteru Oshima : Effects of L-DOPA on haloperidol-induced motor deficits in mice, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1997, 113-120, 1997..[著者] ... Tsutomu Araki, Hiroyuki Kato, Yoshiteru Oshima and Yasuto Itoyama : Role of nitric oxide on age-related changes in second messenger systems and calcium channels in Fischer 344 rats, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1997, 106-112, 1997..[著者] ... Kaoru Ishizaki, Shigemasa Kinbara, Norio Miyazawa, Yoshishige Takeuchi, Norio Hirabayashi, Hiroshi Kasai and Tsutomu Araki : The biochemical studies on phalloidin-induced cholestasis in rats, Toxicology Letters, Vol.90, No.1, 29-34, 1997..[著者] ... Tsutomu Araki, Hiroyuki Kato, Katsuro Shuto, Takehiko Fujiwara and Yasuto Itoyama : Age-related changes of sodium-dependentd-[3H]aspartate and [3H]FK506 binding in rat brain, Journal of Neural Transmission, Vol.104, No.2-3, 259-267, 1997..[著者] ... Hiroyuki Kato, Tsutomu Araki, Ting Chen, Xiao-Hong Liu, T Hiranuma, Kenshi Murase, Yasuto Itoyama and Kyuya Kogure : Effects of chronic treatment with a cyclic AMP-selective phosphodiesterase inhibitor, rolipram, on excitatory amino acid neurotransmission systems in young and aged rat brains, Journal of Neural Transmission, Vol.104, No.2-3, 269-280, 1997..[著者] ... Tsutomu Araki, Hiroyuki Kato, Katsuro Shuto and Yasuto Itoyama : Age-related changes in [3H]nimodipine and [3H]rolipram binding in the rat brain, The Journal of Pharmacy and Pharmacology, Vol.49, No.3, 310-314, 1997..[著者] ... Tsutomu Araki, Hiroyuki Kato, Sumiko Nagaki, Katsuro Shuto, Takehiko Fujiwara and Yasuto Itoyama : Effects of vinconate on age-related alterations in [3H]MK-801, [3H]glycine, sodium-dependent -[3H]aspartate, [3H]FK-506 and [3H]PN200-110 binding in rats, Mechanisms of Ageing and Development, Vol.95, No.1-2, 13-29, 1997..[著者] ... Tsutomu Araki, Hiroyuki Kato, Katsuro Shuto, Takehiko Fujiwara and Yasuto Itoyama : Effect of aging on dopaminergic receptors and uptake sites in the rat brain studied by receptor autoradiography, Journal of the Neurological Sciences, Vol.148, No.2, 131-137, 1997..[著者] ... Tsutomu Araki, Y Oshima, Hiroyuki Kato, Katsuro Shuto and Yasuto Itoyama : Effect of NG-nitro-L-arginine on age-related changes of glutamate receptor systems and immunophilin in rats, Methods and Findings in Experimental and Clinical Pharmacology, Vol.19, No.6, 373-381, 1997..[著者] ... Kaoru Ishizaki, Shigemasa Kinbara, Norio Miyazawa, Yoshishige Takeuchi, Norio Hirabayashi, Hiroshi Kasai and Tsutomu Araki : Effect of sodium tauroursodeoxycholate (UR-906) on liver dysfunction in bile duct-ligated rats, European Journal of Pharmacology, Vol.333, No.2-3, 207-213, 1997..[著者] ... Shigemasa Kinbara, Kaoru Ishizaki, H Sakakura, Norio Hirabayashi, Hiroshi Kasai and Tsutomu Araki : Improvement of estradiol-17β-D-glucuronide-induced cholestasis by sodium tauroursodeoxycholate therapy in rats, Scandinavian Jurnal of Gastroenterology, Vol.32, No.9, 947-952, 1997..[著者] ... Tsutomu Araki, Hiroyuki Kato, Katsuro Shuto, Takehiko Fujiwara and Yasuto Itoyama : Effect of cerebral ischemia on dopamine receptors and uptake sites in the gerbil hippocampus, European Neuropsychopharmacology, Vol.7, No.4, 275-282, 1997..[著者] ... Tsuneyasu Kobayashi, Tsutomu Araki, Yasuto Itoyama, Mitsuhiro Takeshita, Tomihisa Ohta and Yoshiteru Oshima : Effects of L-DOPA and bromocriptine on haloperidol-induced motor deficits in mice, Life Sciences, Vol.61, No.26, 2529-2538, 1997..[著者] ... Tsutomu Araki, Hiroyuki Kato, Kyuya Kogure and Yasuto Itoyama : Post-ischaemic alteration of excitatory amino acid transport sites in the gerbil hippocampus, The Journal of Pharmacy and Pharmacology, Vol.49, No.12, 1234-1238, 1997..[著者] ... Hiroaki Tanji, Tsutomu Araki, Haruo Nagasawa and Yasuto Itoyama : Sequential changes of dopamine uptake sites in the mouse brain after MPTP treatment, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1998, 133-138, 1998..[著者] ... Tsutomu Araki, Hiroyuki Kato, Yoshiteru Oshima and Yasuto Itoyama : Postischemic changes of [3H]nimodipine and [3H]ryanodine binding in the gerbil striatum and hippocampus, European Journal of Neurology, Vol.5, No.2, 195-201, 1998..[著者] ... Tsutomu Araki, Hiroyuki Kato, Katsuro Shuto and Yasuto Itoyama : Post-Ischemic Alterations in [3H]FK506 Binding in the Gerbil and Rat Brains, Metabolic Brain Disease, Vol.13, No.1, 9-19, 1998..[著者] ... H Tanji, Haruo Nagasawa, Tsutomu Araki, J Onodera, S Takase, M Itoh and Yasuto Itoyama : PET study of striatal fluorodopa uptake and dopamine D2 receptor binding in a patient with juvenile parkinsonism, European Journal of Neurology, Vol.5, No.3, 243-248, 1998..[著者] ... Hiroyuki Kato, Tsutomu Araki, Ting Chen, Yasuto Itoyama and Kyuya Kogure : Effect of rolipram on age-related changes in cyclic AMP-selective phosphodiesterase in the rat brain: An autoradiographic study, Methods and Findings in Experimental and Clinical Pharmacology, Vol.20, No.5, 403-408, 1998..[著者] ... Ting Chen, Hiroyuki Kato, Tsutomu Araki, Yasuto Itoyama and Kyuya Kogure : Age-Related Effects of Rolipram on[3H]Quinuclidinyl Benzilate and [3H]Phorbol 12, 13-Dibutyrate Binding in the Rat Brain, The Tohoku Journal of Experimental Medicine, Vol.185, No.2, 107-118, 1998..[著者] ... Kazuhiko Seya, Izumi Miki, Kiyoshi Murata, Hisae Junke, Shigeru Motomura, Tsutomu Araki, Yasuto Itoyama and Yoshiteru Oshima : Pharmacological properties of pteleprenine, a quinoline alkaloid extracted from Orixa japonica, on guinea-pig ileum and canine left atrium, The Journal of Pharmacy and Pharmacology, Vol.50, No.7, 803-807, 1998..[著者] ... Tsutomu Araki, Hiroyuki Kato, Katsuro Shuto and Yasuto Itoyama : Alterations in [3H]L-NG-nitroarginine binding in brain after transient global or transient focal ischemia in gerbils and rats, European Journal of Pharmacology, Vol.354, No.2-3, 153-159, 1998..[著者] ... Tsutomu Araki, Hiroaki Tanji, Hiroyuki Kato and Yasuto Itoyama : Sequential changes of dopaminergic receptors in the rat brain after 6-hydroxydopamine lesions of the medial forebrain bundle, Journal of the Neurological Sciences, Vol.160, No.2, 121-127, 1998..[著者] ... Tsutomu Araki, Yoshiteru Oshima, Hiroyuki Kato, Katsuro Shuto and Yasuto Itoyama : Effect of NG-nitro-L-arginine methyl ester a nitric oxide synthase inhibitor on neurotransmitter receptor systems in aged rats, European Journal of Neurology, Vol.5, No.6, 601-608, 1998..[著者] ... Mitsuhiro Takeshita, Masatomo Miura, Takahiko Hongo, Tadashi Ohkubo, Kazunobu Sugawara, Kazuhiko Kosaka, Yasuyoshi Takeshita, Tsutomu Araki and Yoshiteru Oshima : Enantio/Diastereoselective Syntheses Synthesis and cataleptic effects of optically active dihydrohaloperidols and dihydrobromoperidols, Chirality, Vol.9, No.5-6, 443-445, 1998..[著者] ... Tomomichi Iwaki, Norio Hirabayashi, Norio Miyazawa, Yoshishige Takeuchi, Kaoru Ishizaki, Hiroo Sakakura, Hiroshi Kasai, Minoru Maeda and Tsutomu Araki : The choleretic effects of N-acetylglucosaminides, major urinary metabolites of ursodeoxycholic acid, in bile fistula rats, European Journal of Pharmacology, Vol.363, No.1, 41-48, 1998..[著者] ... Haruo Mizutani, Tsutomu Araki, Mitsunobu Matsubara, Yutaka Imai, Michinao Mizugaki and Yasuto Itoyama : Nitric oxide synthase inhibitors induce motor abnormality in mice, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1999, 117-123, 1999..[著者] ... Tadayoshi Mikami, Tsutomu Araki, Hiroaki Tanji, Yutaka Imai, Michinao Mizugaki and Yasuto Itoyama : Biochemical changes in the brain of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mouse, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.1999, 131-137, 1999..[著者] ... Tsutomu Araki, Hiroaki Tanji, Kazuo Fujihara, Hiroyuki Kato and Yasuto Itoyama : Increases in [3H]FK-506 and [3H]L-NG-Nitro-Arginine Binding in the Rat Brain After Nigrostriatal Dopaminergic Denervation, Metabolic Brain Disease, Vol.14, No.1, 21-31, 1999..[著者] ... Kazuyuki Uchiyama, Daisuke Wakatsuki, Bunpei Kakinoki, Yoshishige Takeuchi, Tsutomu Araki and Yasuhiro Morinaka : Effects of TU-199, a novel H+, K+-ATPase inhibitor, on gastric acid secretion and gastroduodenal ulcers in rats, Methods and Findings in Experimental and Clinical Pharmacology, Vol.21, No.2, 115-122, 1999..[著者] ... Kazuyuki Uchiyama, Daisuke Wakatsuki, Bunpei Kakinoki, Yoshishige Takeuchi, Tsutomu Araki and Yasuhiro Morinaka : The Long-lasting Effect of TU-199, a Novel H+,K+-ATPase Inhibitor, on Gastric Acid Secretion in Dogs, The Journal of Pharmacy and Pharmacology, Vol.51, No.4, 457-464, 1999..[著者] ... Hiroaki Tanji, Tsutomu Araki, Haruo Nagasawa and Yasuto Itoyama : Differential vulnerability of dopamine receptors in the mouse brain treated with MPTP, Brain Research, Vol.824, No.2, 224-231, 1999..[著者] ... Hiroaki Tanji, Tsutomu Araki, Haruo Nagasawa and Yasuto Itoyama : Differential vulnerability of dopamine receptors in mouse brain treated with MPTP, 13th International Congress on Parkinson's Disease, Vancouver, July 1999..[著者] ... Hiroaki Tanji, Tsutomu Araki, Haruo Nagasawa and Yasuto Itoyama : Alterations of neurotensin receptors in MPTP-induced Parkinsonian mice, 13th International Congress on Parkinson's Disease, Vancouver, July 1999..[著者] ... Hiroaki Tanji, Tsutomu Araki, Kazuo Fujihara, Haruo Nagasawa and Yasuto Itoyama : Alteration of neurotensin receptors in MPTP-treated mice, Peptides, Vol.20, No.7, 803-807, 1999..[著者] ... Tsutomu Araki, Hiroaki Tanji, Hiroyuki Kato, Michinao Mizugaki and Yasuto Itoyama : Alterations of second messenger systems in the rat brain after 6-hydroxydopamine lesions of the medial forebrain bundle, European Journal of Pharmaceutical Sciences, Vol.8, No.4, 261-267, 1999..[著者] ... Hiroyuki Kato, K Otsuka, Tsutomu Araki, T Oikawa, A Takahashi and Yasuto Itoyama : The role of immunophilin FKBP12 in cerebral ischemia, The 4th International Workshop on Maturation Phenomenon in Cerebral Ischemia, 1999..[著者] ... T Oikawa, Tsutomu Araki, Hiroyuki Kato, A Takahashi and Yasuto Itoyama : Alterations in {3H}L-NG-nitroarginine binding in the rat brain after transient global and focal ischemia in gerbils and rats, The 4th International Workshop on Maturation Phenomenon in Cerebral Ischemia, 1999..[著者] ... Megumi Akasaka, M Kumagai, T Ido, Tsutomu Araki, Mitsunobu Matsubara, Yutaka Imai and Yasuto Itoyama : Protective effect of riluzole on MPTP-induced depletion of dopamine and its metbolite content in mice, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.2000, (号), 84-88, 2000..[著者] ... Hiroaki Tanji, Tsutomu Araki, Hiroyuki Kato, Yutaka Imai, Michinao Mizugaki and Yasuto Itoyama : Sequential changes of [3H]forskolin, [3H]cyclohexyladenosine and [3H]PN200-110 binding sites in the brain of 6-hydroxydopamine-lesioned rats, Acta Physiologica Scandinavica, Vol.169, No.1, 71-78, 2000..[著者] ... Mitsunobu Matsubara, Takayoshi Ohkubo, Mari Michimata, Atsushi Hozawa, Kazuhiko Ishikawa, Tomohiro Katsuya, Kenichi Nagai, Ichiro Tsuji, Jitsuo Higaki, Tsutomu Araki, Hiroshi Satoh, Shigeru Hisamichi, Sadayoshi Ito, Toshio Ogihara and Yutaka Imai : Japanese individuals do not harbor the T594M mutation but do have the P592S mutation in the C-terminus of the β-subunit of the epithelial sodium channel: the Ohasama Study, Journal of Hypertension, Vol.18, No.7, 861-866, 2000..[著者] ... Tsutomu Araki, Hiroaki Tanji, Kazuo Fujihara, Hiroyuki Kato, Yutaka Imai, Michinao Mizugaki and Yasuto Itoyama : Sequential changes of cholinergic and dopaminergic receptors in brains after 6-hydroxydopamine lesions of the medial forebrain bundle in rats, Journal of Neural Transmission, Vol.107, No.8-9, 873-884, 2000..[著者] ... Tsutomu Araki, Hiroaki Tanji, Hiroyuki Kato, Yutaka Imai, Michinao Mizugaki and Yasuto Itoyama : Temporal changes of dopaminergic and glutamatergic receptors in 6-hydroxydopamine-treated rat brain, European Neuropsychopharmacology, Vol.10, No.5, 365-375, 2000..[著者] ... Tsutomu Araki, Toshihiko Kumagai, Mitsunobu Matsubara, Tatsuo Ido, Yutaka Imai and Yasuto Itoyama : Protective effect of riluzole on MPTP-induced depletion of dopamine and its metabolite content in mice, Metabolic Brain Disease, Vol.15, No.3, 193-201, 2000..[著者] ... Masahiro Kikuya, Atsushi Hozawa, Takayoshi Ohokubo, Ichiro Tsuji, Mari Michimata, Mitsunobu Matsubara, Masahiro Ota, Kenichi Nagai, Tsutomu Araki, Hiroshi Satoh, Sadayoshi Ito, Shigeru Hisamichi and Yutaka Imai : Prognostic Significance of Blood Pressure and Heart Rate Variabilities : The Ohasama Study, Hypertension, Vol.36, No.5, 901-906, 2000..[著者] ... Hiroyuki Kato, Tsutomu Araki, T Mikami, Yutaka Imai, M Mizuaki, A Takahashi and Yasuto Itoyama : Neuroprotection by ONO-2506 in MPTP-mouse model of Parkinson's disease, 30th Annual Meeting, Society for Neuroscience, New Orleans, Nov. 2000..[著者] ... Hiroyuki Kato, K Otsuka, Tsutomu Araki, T Oikawa, Akira Takahashi and Yasuto Itoyama : Maturation Phenomenon in Cerebral Ischemia IV, --- The role of the immunophilin FKBP12 in cerebral ischemia ---, Springer-Verlag, (都市), (month)2001..[著者] ... 村松 靖子, 荒木 勉 : 難治性の神経変性疾患Parkinson病の病態解明と薬物療法に関する基礎的研究, 東北大学CYRICニュース, Vol.31, (号), 4-7, 2001年(0月)..[著者] ... Toshihiko Kumagai, Tatsuo Ido, Tsutomu Araki, Mitsunobu Matsubara and Yasuto Imai : Riluzole protects against MPTP-induced dopamine and DOPAC depletion in mice, Biogenic Amines, Vol.16, No.2, 157-172, 2001..[著者] ... Rumiko Kurosaki, Yasuko Muramatsu, Hijiri Watanabe, Mari Michimata, Mitsunobu Matsubara, Yutaka Imai, Shuichi Kimura and Tsutomu Araki : Effect of angiotensin-converting enzyme inhibitor against MPTP neurotoxicity in mice:An immunohistochemical study, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.2001, 116-122, 2001..[著者] ... Yasuko Muramatsu, Rumiko Kurosaki, Hijiri Watanabe, Mari Michimata, Mitsunobu Matsubara, Yutaka Imai, Shuichi Kimura and Tsutomu Araki : Neuroprotective effect of riluzole against MPTP neurotoxicity, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.2001, 123-128, 2001..[著者] ... Hijiri Watanabe, Yasuko Muramatsu, Rumiko Kurosaki, Mari Michimata, Mitsunobu Matsubara, Yutaka Imai, Shuichi Kimura and Tsutomu Araki : Neuronal nitric oxide synthase inhibitor and monoamine oxidase B inhibitor attenuate MPTP Neurotoxicity, CYRIC annual report / Cyclotron and Radioisotope Center, Tohoku University, Vol.2001, 129-143, 2001..[著者] ... Tsutomu Araki, Tadayoshi Mikami, Hiroaki Tanji, Mitsunobu Matsubara, Yutaka Imai, Michinao Mizugaki and Yasuto Itoyama : Biochemical and immunohistological changes in the brain of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mouse, European Journal of Pharmaceutical Sciences, Vol.12, No.3, 231-238, 2001..[著者] ... Yutaka Imai, Takayoshi Ohkubo, Atsushi Hozawa, Ichiro Tsuji, Mitsunobu Matsubara, Tsutomu Araki, Kenichi Chonan, Masahiro Kikuya, Hiroshi Satoh, Shigeru Hisamichi and Kenichi Nagai : Usefulness of home blood pressure measurements in assessing the effect of treatment in a single-blind placebo-controlled open trial, Journal of Hypertension, Vol.19, No.2, 179-185, 2001..[著者] ... Tsutomu Araki, Haruo Mizutani, Mitsunobu Matsubara, Yutaka Imai, Michinao Mizugaki and Yasuto Itoyama : Nitric oxide synthase inhibitors cause motor deficits in mice, European Neuropsychopharmacology, Vol.11, No.2, 125-133, 2001..[著者] ... 加藤 宏之, 荒木 勉, 今井 潤, 高橋 明, 糸山 泰人 : パーキンソン病モデルマウスにおけるNOS阻害剤とMAO阻害剤の脳保護作用, 第9回カテコールアミンと神経疾患研究会, 2001年4月..[著者] ... Hiroyuki Kato, Tsutomu Araki, Yutaka Imai, Akira Takahashi and Yasuto Itoyama : Comparative neuroprotective effects of nNOS inhibitors and MAO inhibitors in the MPTP-mouse model of Parkinson's disease, 20th International Symposium on Cerebral Blood Flow and Metabolisms(BRAIN 01), Taipei, June 2001..[著者] ... Mari Michimata, Weihua Wang, Sayuri Fujita, Haruo Mizutani, Keisei Fujimori, Susumu Satomi, Masahiro Ohta, Sadayoshi Ito, Tokihisa Kimura, Tsutomu Araki, Yutaka Imai and Mitsunobu Matsubara : Limited urinary concentration and damaged tubules in rats with a syngeneic kidney graft, Kidney International, Vol.60, No.2, 672-679, 2001..[著者] ... Kenichi Chonan, Masahiro Kikuya, Tsutomu Araki, Tohru Fujiwara, Michiko Suzuki, Mari Michimata, Junichiro Hashimoto, Takayoshi Ohkubo, Atsushi Hozawa, Norihito Yamamoto, Yoshinori Miyawaki, Mitsunobu Matsubara and Yutaka Imai : Device for the self-measurement of blood pressure that can monitor blood pressure during sleep, Blood Pressure Monitoring, Vol.6, No.4, 203-205, 2001..[著者] ... 黒崎 瑠美子, 村松 靖子, 荒木 勉, 木村 修一 : MPTP誘発パーキンソン病モデルマウスの病態解析, 第12回マイクロダイアリシス研究会, 2001年10月..[著者] ... 大森 史子, 松原 光伸, 荒木 勉, 今井 潤 : 日本人におけるCYP11B2遺伝子多型と高血圧, 第40回日本薬学会東北支部大会, 2001年10月..[著者] ... 田中 克幸, 赤坂 恵, 松原 光伸, 荒木 勉, 今井 潤, 井戸 達雄 : 降圧剤のMPTP誘発Parkinson病モデルマウスに対する検討, 第40回日本薬学会東北支部大会, 2001年10月..[著者] ... 藤田 早由里, 道又 真理, 水上 和彦, 青木 洋平, 松原 光伸, 荒木 勉, 今井 潤 : Li中毒による腎性尿崩症の機序の分子生物学的検討, 第40回日本薬学会東北支部大会, 2001年10月..[著者] ... 赤坂 恵, 田中 克幸, 井戸 達雄, 松原 光伸, 荒木 勉, 今井 潤 : 加齢に伴うDopamine代謝及び行動薬理学的検討, 第40回日本薬学会東北支部大会, 2001年10月..[著者] ... Tsutomu Araki, Yasuko Muramatsu, Katsuyuki Tanaka, Mitsunobu Matsubara and Yutaka Imai : Riluzole (2-amino-6-trifluoromethoxy benzothiazole) attenuates MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in mice, Neuroscience Letters, Vol.312, No.1, 50-54, 2001..[著者] ... Mitsunobu Matsubara, Fumiko Omori, Sayuri Fujita, Hirohito Metoki, Masahiro Kikuya, Tohru Fujiwara, Tsutomu Araki and Yutaka Imai : Haplotypes of aldosterone synthase (CYP11B2) gene in the general population of Japan: the Ohasama study, Clinical and Experimental Hypertension, Vol.23, No.8, 603-610, 2001..[著者] ... Tsutomu Araki, Toshihiko Kumagai, Katsuyuki Tanaka, Mitsunobu Matsubara, Hiroyuki Kato, Yasuto Itoyama and Yutaka Imai : Neuroprotective effect of riluzole in MPTP-treated mice, Brain Research, Vol.918, No.1-2, 176-181, 2001..[著者] ... Hiroyuki Kato, Tsutomu Araki, Yutaka Imai, Akira Takahashi and Yasuto Itoyama : Astroglia-mediated neuroprotection by ONO-2506 against MPTP neurotoxicity in mice, 31th Annual Meeting of the Society for Neuroscience, San Diego, Nov. 2001..[著者] ... Mitsunobu Matsubara, Masahiro Kikuya, Takayoshi Ohkubo, Hirohito Metoki, Fumiko Omori, Tohru Fujiwara, Michiko Suzuki, Mari Michimata, Atsushi Hozawa, Tomohiro Katsuya, Jitsuo Higaki, Ichiro Tsuji, Tsutomu Araki, Toshio Ogihara, Hiroshi Satoh, Shigeru Hisamichi, Kenichi Nagai, Hirofumi Kitaoka and Yutaka Imai : Aldosterone synthase gene (CYP11B2) C-334T polymorphism, ambulatory blood pressure and nocturnal decline in blood pressure in the general Japanese population: the Ohasama Study, Journal of Hypertension, Vol.19, No.12, 2179-2184, 2001..[著者] ... 黒崎 瑠美子, 村松 靖子, 荒木 勉, 木村 修一 : パーキンソン病モデルマウスの病態解析, 第12回マイクロダイアリシス研究会, 2001年12月..[著者] ... Takashi Asai, Takayoshi Ohkubo, Tomohiro Katsuya, Jitsuo Higaki, Yuxiao Fu, Masayuki Fukuda, Atsushi Hozawa, Mitsunobu Matsubara, Hirofumi Kitaoka, Ichiro Tsuji, Tsutomu Araki, Hiroshi Satoh, Shigeru Hisamichi, Yutaka Imai and Toshio Ogihara : Endothelin-1 Gene Variant Associates With Blood Pressure in Obese Japanese Subjects: The Ohasama Study, Hypertension, Vol.38, No.6, 1321-1324, 2001..[著者] ... Tsutomu Araki : The role of nitric oxide on motor activity, Brain Pharmacology, Vol.1, (号), 121-127, (month)2002..[著者] ... H Mizutani, Yasuko Muramatsu and Tsutomu Araki : Differential roles between dopaminergic and serotonergic system on motor deficits in mice, Brain Pharmacology, Vol.1, (号), 253-266, 2002..[著者] ... 加藤 宏之, 荒木 勉, 高橋 明, 糸山 泰人 : パーキンソン病モデルマウスにおけるNOS阻害薬とMAO阻害薬の脳保護作用, Progress in Medicine, Vol.22, No.1, 206-209, 2002年..[著者] ... 黒崎 瑠美子, 荒木 勉, 加藤 宏之, 木村 修一 : 実験的パーキンソン病モデルマウスにおける基礎的検討, Progress in Medicine, Vol.22, (号), 2894-2900, 2002年..[著者] ... Tsutomu Araki, Mitsunobu Matsubara, Kazuo Fujihara, Hiroyuki Kato, Yutaka Imai and Yasuto Itoyama : Gamma aminobutyric acidA and benzodiazepine receptor alterations in the rat brain after unilateral 6-hydroxydopamine lesions of the medial forebrain bundle, Neurological Research, Vol.24, No.1, 107-112, 2002..[著者] ... Mitsunobu Matsubara, Hirohito Metoki, Michiko Suzuki, Tohru Fujiwara, Masahiro Kikuya, Mari Michimata, Takayoshi Ohkubo, Atsushi Hozawa, Ichiro Tsuji, Shigeru Hisamichi, Tsutomu Araki and Yutaka Imai : Genotypes of the βENaC gene have little influence on blood pressure level in the Japanese population, American Journal of Hypertension, Vol.15, No.2, 189-192, 2002..[著者] ... Masayuki Fukuda, Takayoshi Ohkubo, Tomohiro Katsuya, Atsushi Hozawa, Takashi Asai, Mitsunobu Matsubara, Hirofumi Kitaoka, Ichiro Tsuji, Tsutomu Araki, Hiroshi Satoh, Jitsuo Higaki, Shigeru Hisamichi, Yutaka Imai and Toshio Ogihara : Association of a Mast Cell Chymase Gene Variant with HDL Cholesterol, but not with Blood Pressure in the Ohasama Study, Hypertension Research, Vol.25, No.2, 179-184, 2002..[著者] ... 佐藤 ともみ, 鈴木 倫子, 松原 光伸, 大森 史子, 西村 拓矢, 道又 真理, 荒木 勉, 今井 潤 : 日本人における上皮性ナトリウムチャンネル(EnaC) βサブユニットの遺伝子多型, 第122年会日本薬学会, 2002年3月..[著者] ... 水上 和彦, 道又 真理, 松原 光伸, 荒木 勉, 藤田 早由里, 西村 拓矢, 今井 潤 : 抗利尿ホルモン非依存性の尿濃縮機構の検討, 第122年会日本薬学会, 2002年3月..[著者] ... 村松 靖子, 赤坂 恵, 道又 真理, 松原 光伸, 荒木 勉, 今井 潤 : MPTP誘発パーキンソン病モデルマウスの病態解析, 第122年会日本薬学会, 2002年3月..[著者] ... 松原 光伸, 荒木 勉, 今井 潤 : カッツング薬理学 原書8版, --- III 心血管と腎臓の薬剤 11. 抗高圧薬の部 pp163-193,X 特殊な題目 66. 医薬品の適正使用と処方箋の書き方の部 pp1227-1235 ---, 丸善 株式会社, 東京, 2002年3月..[著者] ... 黒崎 瑠美子, 荒木 勉, 加藤 宏之, 木村 修一 : 実験的パーキンソン病モデルマウスにおける基礎的検討, 第10回カテコールアミンと神経疾患研究会, 2002年4月..[著者] ... Kenichi Chonan, Junichiro Hashimoto, Takayoshi Ohkubo, Ichiro Tsuji, Kenichi Nagai, Masahiro Kikuya, Atsushi Hozawa, Mitsunobu Matsubara, Michiko Suzuki, Tohru Fujiwara, Tsutomu Araki, Hiroshi Satoh, Shigeru Hisamichi and Yutaka Imai : Insufficient duration of action of antihypertensive drugs mediates high blood pressure in the morning in hypertensive population: The Ohasama Study, Clinical and Experimental Hypertension, Vol.24, No.4, 261-275, 2002..[著者] ... Mitsunobu Matsubara, Michiko Suzuki, Tohru Fujiwara, Masahiro Kikuya, Hirohito Metoki, Mari Michimata, Tsutomu Araki, Itsuro Kazama, Tomomi Satoh, Junichiro Hashimoto, Atsushi Hozawa, Takayoshi Ohkubo, Ichiro Tsuji, Tomohiro Katsuya, Jitsuo Higaki, Toshio Ogihara, Hiroshi Satoh and Yutaka Imai : Angiotensin-converting enzyme I/D polymorphism and hypertension: The Ohasama study, Journal of Hypertension, Vol.20, No.6, 1121-1126, 2002..[著者] ... Tohru Fujiwara, Tomohiro Katsuya, Mitsunobu Matsubara, Tadayoshi Mikami, Kazuhiko Ishikawa, Masahiro Kikuya, Takayoshi Ohkubo, Atsushi Hozawa, Mari Michimata, Michiko Suzuki, Hirohito Metoki, Kei Asayama, Tsutomu Araki, Ichiro Tsuji, Jitsuo Higaki, Hiroshi Satoh, Shigeru Hisamichi, Toshio Ogihara and Yutaka Imai : T+31C polymorphism of angiotensinogen gene and nocturnal blood pressure decline: the Ohasama study, American Journal of Hypertension, Vol.15, No.7, 628-632, 2002..[著者] ... Rumiko Kurosaki, Yasuko Muramatsu, Tsutomu Araki and Shuichi Kimura : Biochemical and immunohistochemical changes in the mouse brain against MPTP neurotoxicity -pharmacological approach, 25th Annual Meeting of Japanese Society for Neurochemistry, July 2002..[著者] ... 黒崎 瑠美子, 村松 靖子, 荒木 勉, 木村 修一 : MPTP誘発パーキンソン病モデルマウスの病態解析及び薬物療法に関する検討, 第25回日本神経科学大会, 2002年7月..[著者] ... Yasuko Muramatsu, Rumiko Kurosaki, Tadayoshi Mikami, Mari Michimata, Mitsunobu Matsubara, Yutaka Imai, Hiroyuki Kato, Yasuto Itoyama and Tsutomu Araki : Therapeutic Effect of Neuronal Nitric Oxide Synthase Inhibitor (7-Nitroindazole) against MPTP Neurotoxicity in Mice, Metabolic Brain Disease, Vol.17, No.3, 169-182, 2002..[著者] ... Shoji Nogae, Mari Michimata, Tsutomu Araki, Michiko Suzuki, Itsuro Kazama, Sadayoshi Ito, Yutaka Imai and Mitsunobu Matsubara : Detection of mRNA for Alpha-3 Chain of Type IV Collagen in the Glomerular Epithelium, and the Effect of Perfused Elastase on Its Expression, Nephron, Vol.92, No.4, 853-859, 2002..[著者] ... Rumiko Kurosaki, Yasuko Muramatsu, Mari Michimata, Mitsunobu Matsubara, Hiroyuki Kato, Yutaka Imai, Yasuto Itoyama and Tsutomu Araki : Role of nitric oxide synthase against MPTP neurotoxicity in mice, Neurological Research, Vol.24, No.7, 655-662, 2002..[著者] ... 村松 靖子, 黒崎 瑠美子, 渡部 聖, 道又 真理, 松原 光伸, 荒木 勉, 今井 潤 : 一過性脳虚血砂ネズミにおけるグリア細胞の役割, 第41回日本薬学会東北支部大会, 2002年..[著者] ... 佐藤 ともみ, 鈴木 倫子, 舟橋 仁, 道又 真理, 荒木 勉, 今井 潤, 松原 光伸 : 日本人におけるレニンーアンギオテンシンーアルドステロン系の主要遺伝子多型と高血圧, --- 24時間自由行動下血圧を用いた解析 ---, 第41回日本薬学会東北支部大会, 2002年..[著者] ... 水上 和彦, 道又 真理, 風間 逸郎, 中村 洋介, 荒木 勉, 今井 潤, 松原 光伸 : 腎不全におけるNaトランスポーターと水チャンネルの発現, --- 尿濃縮機構の機序についての検討 ---, 第41回日本薬学会東北支部大会, 2002年..[著者] ... 中村 洋介, 道又 真理, 水上 和彦, 風間 逸郎, 荒木 勉, 今井 潤, 松原 光伸 : 先天性尿崩症モデルラットにおけるNaトランスポーターと水チャンネルの発現, --- 抗利尿ホルモン非依存性の尿濃縮機構の検討 ---, 第41回日本薬学会東北支部大会, 2002年..[著者] ... 渡部 聖, 村松 靖子, 黒崎 瑠美子, 道又 真理, 松原 光伸, 荒木 勉, 今井 潤 : MPTP誘発パーキンソン病モデルマウスにおける神経細胞保護作用に関する検討, 第41回日本薬学会東北支部大会, 2002年..[著者] ... Yasuko Muramatsu and Tsutomu Araki : Glial cells as a target for the development of new therapies for treating Parkinson's disease, Drug News Perspect, Vol.15, No.9, 586-590, Nov. 2002..[著者] ... Takayoshi Ohkubo, Atsushi Hozawa, Junko Yamaguchi, Masahiro Kikuya, Kaori Ohmori, Mari Michimata, Mitsunobu Matsubara, Junichiro Hashimoto, Haruhisa Hoshi, Tsutomu Araki, Ichiro Tsuji, Hiroshi Satoh, Shigeru Hisamichi and Yutaka Imai : Prognostic significance of the nocturnal decline in blood pressure in individuals with and without high 24-h blood pressure: the Ohasama study, Journal of Hypertension, Vol.20, No.11, 2183-2189, 2002..[著者] ... Junichiro Hashimoto, Kenichi Chonan, Yohei Aoki, Takuya Nishimura, Takayoshi Ohkubo, Atsushi Hozawa, Michiko Suzuki, Mitsunobu Matsubara, Mari Michimata, Tsutomu Araki and Yutaka Imai : Pulse wave velocity and the second derivative of the finger photoplethysmogram in treated hypertensive patients: their relationship and associating factors, Journal of Hypertension, Vol.20, No.12, 2415-2422, 2002..[著者] ... 荒木 勉 : 「パーキンソン病の病態解明と今後の展望」に関する講演, 宮城県薬剤師会, 2002年12月..[著者] ... 黒崎 瑠美子, 木村 修一, 村松 靖子, 加藤 宏之, 荒木 勉 : パーキンソン病モデルマウスの病態解析における基礎的検討, Progress in Medicine, Vol.23, 2730-2735, 2003年..[著者] ... Mari Michimata, Sayuri Fujita, Tsutomu Araki, Kazuhiko Mizukami, Itsuro Kazama, Yasuko Muramatsu, Michiko Suzuki, Tokihisa Kimura, Sei Sasaki, Yutaka Imai and Mitsunobu Matsubara : Reverse pharmacological effect of loop diuretics and altered rBSC1 expression in rats with lithium nephropathy, Kidney International, Vol.63, No.1, 165-171, 2003..[著者] ... Mitsunobu Matsubara, Hirohito Metoki, Tomohiro Katsuya, Masahiro Kikuya, Michiko Suzuki, Mari Michimata, Tsutomu Araki, Atsushi Hozawa, Ichiro Tsuji, Toshio Ogihara and Yutaka Imai : T+31C Polymorphism (M235T) of the Angiotensinogen Gene and Home Blood Pressure in the Japanese General Population: the Ohasama Study, Hypertension Research, Vol.26, No.1, 47-52, 2003..[著者] ... Yutaka Imai, Atsushi Hozawa, Takayoshi Ohkubo, Kaori Ohmori, Masahiro Kikuya, Junichiro Hashimoto, Mari Michimata, Mistunobu Matsubara, Junko Yamaguchi, Takashi Ugajin, Tsutomu Araki and Ichiro Tsuji : Heart rate measurement and outcome, Blood Pressure Monitoring, Vol.8, No.1, 53-55, 2003..[著者] ... Mari Michimata, Itsuro Kazama, Kazuhiko Mizukami, Tsutomu Araki, Yohsuke Nakamura, Michiko Suzuki, Weihua Wang, Keisei Fujimori, Susumu Satomi, Sadayoshi Ito, Yutaka Imai and Mitsunobu Matsubara : Urinary Concentration Defect and Limited Expression of Sodium Cotransporter, rBSC1, in a Rat Model of Chronic Renal Failure, Nephron. Physiology, Vol.93, No.2, 34-41, 2003..[著者] ... Masahiro Kikuya, Ken Sugimoto, Tomohiro Katsuya, Michiko Suzuki, Tomomi Sato, Jin Funahashi, Ryusuke Katoh, Itsuro Kazama, Mari Michimata, Tsutomu Araki, Atsushi Hozawa, Ichiro Tsuji, Toshio Ogihara, Teruyuki Yanagisawa, Yutaka Imai and Mitsunobu Matsubara : A/C1166 Gene Polymorphism of the Angiotensin II Type 1 Receptor (AT1) and Ambulatory Blood Pressure: the Ohasama Study, Hypertension Research, Vol.26, No.2, 141-145, 2003..[著者] ... Rumiko Kurosaki, Megumi Akasaka, Mari Michimata, Mitsunobu Matsubara, Yutaka Imai and Tsutomu Araki : Effects of Ca2+ antagonists on motor activity and the dopaminergic system in aged mice, Neurobiology of Aging, Vol.24, No.2, 315-319, 2003..[著者] ... Yasuko Muramatsu, Rumiko Kurosaki, Hijiri Watanabe, Mari Michimata, Mitsunobu Matsubara, Yutaka Imai and Tsutomu Araki : Expression of S-100 protein is related to neuronal damage in MPTP-treated mice, Glia, Vol.42, No.3, 307-311, 2003..[著者] ... Junichiro Hashimoto, Kenichi Chonan, Yohei Aoki, Takashi Ugajin, Junko Yamaguchi, Takuya Nishimura, Masahiro Kikuya, Mari Michimata, Mitsunobu Matsubara, Tsutomu Araki, Atsushi Hozawa, Takayoshi Ohkubo and Yutaka Imai : Therapeutic effects of evening administration of guanabenz and clonidine on morning hypertension: evaluation using home-based blood pressure measurements, Journal of Hypertension, Vol.21, No.4, 805-811, 2003..[著者] ... 黒崎 瑠美子, 木村 修一, 村松 靖子, 加藤 宏之, 荒木 勉 : パーキンソン病モデルマウスの病態解析における基礎的検討, 第11回カテコールアミンと神経疾患研究会, 2003年4月..[著者] ... Hiroyuki Kato, Tsutomu Araki, Yutaka Imai, Akira Takahashi and Yasuto Itoyama : Ptotection of dopamininergic neurons with a novel astrocyte modulating agent (R)-(-)2-propyloctanoic acid (ONO-2506) in an MPTP-treated mouse model of Parkinson's disease, Journal of the Neurological Sciences, Vol.208, No.1-2, 9-15, 2003..[著者] ... Rumiko Kurosaki, Yasuko Muramatsu, Hijiri Watanabe, Mari Michimata, Mitsunobu Matsubara, Yutaka Imai and Tsutomu Araki : Role of Dopamine Transporter Against MPTP (1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine) Neurotoxicity in Mice, Metabolic Brain Disease, Vol.18, No.2, 139-146, 2003..[著者] ... Ruriko Kurosaki and Tsutomu Araki : Dopamine transporter and neurodegeneration, Current Topics in Pharmacology, Vol.1, No.7, 125-132, July 2003..[著者] ... Rumiko Kurosaki, Yasuko Muramatsu, Shuichi Kimura and Tsutomu Araki : Effects of Ca2+ antagonists on motor activity and the dopaminergic system in aged mice, 26th Annual Meeting of Japanese Society for Neurochemistry, July 2003..[著者] ... Yasuko Muramatsu, Rumiko Kurosaki, Hijiri Watanabe, Mari Michimata, Mitsunobu Matsubara, Yutaka Imai and Tsutomu Araki : Cerebral alterations in a MPTP-mouse model of Parkinson's disease, --- an immunohistochemistry ---, Journal of Neural Transmission, Vol.110, No.10, 1129-1144, 2003..[著者] ... 黒崎 瑠美子, 村松 靖子, 木村 修一, 荒木 勉 : 実験的パーキンソン病モデルマウスの基礎的検討と応用, 第14回マイクロダイアリシス研究会, 2003年10月..[著者] ... 黒崎 瑠美子, 村松 靖子, 木村 修一, 荒木 勉 : 実験的パーキンソン病モデルマウスの基礎的検討と応用, 第13回マイクロダイアリシス研究会, 2003年12月..[著者] ... Yohei Aoki, Kei Asayama, Takayoshi Ohkubo, Takuya Nishimura, Masahiro Kikuya, Hirohito Metoki, Atsushi Hozawa, Junichiro Hashimoto, Mari Michimata, Mitsunobu Matsubara, Tsutomu Araki and Yutaka Imai : Progress Report on the HOMED-BP Study: Hypertension Objective Treatment Based on Measurement by Electrical Devices of Blood Pressure Study, Clinical and Experimental Hypertension, Vol.26, No.2, 119-127, 2004..[著者] ... Hiroshi Maeno, Kazuyuki Yamada, Yuko Santo-Yamada, Kumiko Aoki, Ying-Jie Sun, Eiichi Sato, Tatsuo Fukushima, Hiroo Ogura, Tsutomu Araki and Sari Kamichi : Comparison of mice deficient in the high- or low-affinity neurotensin receptors, Ntsr1 or Ntsr2, reveals a novel function for Ntsr2 in thermal nociception, Brain Research, Vol.998, No.1, 122-129, 2004..[著者] ... Hijiri Watanabe, Yasuko Muramatsu, Rumiko Kurosaki, Mari Michimata, Mitsunobu Matsubara, Yutaka Imai and Tsutomu Araki : Protective effects of neuronal nitric oxide synthase inhibitor in mouse brain against MPTP neurotoxicity: an immunohistological study, European Neuropsychopharmacology, Vol.14, No.2, 93-104, 2004..[著者] ... 渡辺 悠, 神原 史織, 水野 くみ子, 姫田 敏樹, 加藤 宏之, 荒木 勉 : 実験的パーキンソン病モデルマウスにおけるグリア細胞の役割, 第12回カテコールアミンと神経疾患研究会, 2004年4月..[著者] ... Rumiko Kurosaki, Yasuko Muramatsu, Hiroyuki Kato and Tsutomu Araki : Biochemical, behavioral and immunohistochemical alterations in MPTP-treated mouse model of Parkinson's disease, Pharmacology, Biochemistry, and Behavior, Vol.78, No.1, 143-153, 2004..[著者] ... 加藤 宏之, 黒崎 瑠美子, 荒木 勉 : グリア機能調整薬ONO-2506によるパーキンソン病の神経細胞保護と神経症状改善, 第45回日本神経学会総会, 2004年6月..[著者] ... 姫田 敏樹, 神原 史織, 荒木 勉 : 高齢マウスにおける自発運動性およびドパミン作動性神経に対するニルバジピンの効果, Pharma Medica, Vol.22, No.8, 141-148, 2004年..[著者] ... Rumiko Kurosaki, Yasuko Muramatsu, Yutaka Imai, Hiroyuki Kato and Tsutomu Araki : Neuroprotective effect of the angiotensin-converting enzyme inhibitor perindopril in MPTP-treated mice, Neurological Research, Vol.26, No.6, 644-657, 2004..[著者] ... Rumiko Kurosaki, Yasuko Muramatsu, Hiroyuki Kato and Tsutomu Araki : Protective effect of pitavastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor, on ischemia-induced neuronal damage, Neurological Research, Vol.26, No.6, 684-691, 2004..[著者] ... Yasuko Muramatsu, Rumiko Kurosaki, Hiroyuki Kato and Tsutomu Araki : Effect of pitavastatin against expression of S100β protein in the gerbil hippocampus after transient cerebral ischaemia, Acta Physiologica Scandinavica, Vol.182, No.1, 95-107, 2004..[著者] ... R Kumagai, Chie Oki, Yasuko Muramatsu, Rumiko Kurosaki, Hiroyuki Kato and Tsutomu Araki : Pitavastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor, reduces hippocampal damage after transient cerebral ischemia in gerbils, Journal of Neural Transmission, Vol.111, No.9, 1103-1120, 2004..[著者] ... 渡辺 悠, 神原 史織, 水野 くみ子, 姫田 敏樹, 加藤 宏之, 荒木 勉 : 実験的パーキンソン病モデルマウスにおけるグリア細胞の役割, Progress in Medicine, Vol.24, No.11, 458-465, 2004年..[著者] ... 渡辺 悠, 神原 史織, 水野 くみ子, 姫田 敏樹, 加藤 宏之, 荒木 勉 : 実験的パーキンソン病モデルマウスにおけるグリア細胞の役割, Progress in Medicine, Vol.24, No.11, 3072-3079, 2004年..[著者] ... 黒崎 瑠美子, 荒木 勉, 木村 修一 : 内因性抗酸化物Carnosineのストレス抵抗性に関する検討, 第15回マイクロダイアリシス研究会, 2004年12月..[著者] ... Hiroyuki Kato, Rumiko Kurosaki, Chie Oki and Tsutomu Araki : Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTP neurotoxicity in mice, Brain Research, Vol.1030, No.1, 66-73, 2004..[著者] ... 門口 直仁, 早川 夏美, 姫田 敏樹, 加藤 宏之, 荒木 勉 : パーキンソン病モデルマウスを用いたarundic acid の神経保護効果の検討, 脳21, Vol.8, No.3, 345, 2005年..[著者] ... Yu Watanabe, Toshiki Himeda and Tsutomu Araki : Mechanisms of MPTP toxicity and their implications for therapy of Parkinson's disease, Medical Science Monitor, Vol.11, No.1, RA17-23, Jan. 2005..[著者] ... Rumiko Kurosaki, Yasuko Muramatsu, Hiroyuki Kato, Yu Watanabe, Yutaka Imai, Yasuto Itoyama and Tsutomu Araki : Effect of angiotensin-converting enzyme inhibitor perindopril on interneurons in MPTP-treated mice, European Neuropsychopharmacology, Vol.15, No.1, 57-67, 2005..[著者] ... 佐久間 美央, 早川 夏美, 藤内 寛子, 姫田 敏樹, 荒木 勉 : 加齢に伴う神経障害に対するニルバジピンの保護効果, Therapeutic Research, Vol.26, No.2, 255-261, 2005年..[著者] ... 門口 直仁, 早川 夏美, 姫田 敏樹, 加藤 宏之, 荒木 勉 : パーキンソン病モデルマウスを用いたarundic acid の神経保護効果の検討, 第13回カテコールアミンと神経疾患研究会, 2005年4月..[著者] ... Toshiki Himeda, Shiori Kanbara, Chie Oki, Hiroyuki Kato and Tsutomu Araki : Effects of chronic administration with nilvadipine against immunohistochemical changes related to aging in the mouse hippocampus, Metabolic Brain Disease, Vol.20, No.2, 141-153, 2005..[著者] ... 藤内 寛子, 姫田 敏樹, 神山 裕子, 水野 くみ子, 荒木 勉 : ピタバスタチン(HMG-CoA還元酵素阻害剤)の虚血性脳障害に対する神経保護効果, Therapeutic Research, Vol.26, No.6, 1269-1276, 2005年..[著者] ... 沖 千絵, 姫田 敏樹, 早川 夏美, 佐久間 美央, 門口 直仁, 荒木 勉 : 一過性脳虚血スナネズミの遅発性神経細胞死に対するピタバスタチン(HMG-CoA 還元酵素阻害剤)の抗酸化作用, Therapeutic Research, Vol.26, No.6, 1277-1286, 2005年..[著者] ... Rumiko Kurosaki, Yu Watanabe and Tsutomu Araki : Effect of angiotensin-converting enzyme inhibitor perindopril on interneurons in MPTP-treated mice, 28th Annual Meeting of Japanese Society for Neurochemistry, June 2005..[著者] ... Toshiki Himeda, Kumiko Mizuno, Hiroyuki Kato and Tsutomu Araki : Effects of age on immunohistochemical changes in the mouse hippocampus, Mechanisms of Ageing and Development, Vol.126, No.6-7, 673-677, 2005..[著者] ... 沖 千絵, 門口 直仁, 早川 夏美, 姫田 敏樹, 荒木 勉 : パーキンソン病モデルマウスを用いたarundic acidの神経細胞保護効果, 第6回長井長義記念シンポジウム, 2005年7月..[著者] ... 早川 夏美, 佐久間 美央, 籐内 寛子, 姫田 敏樹, 荒木 勉 : 加齢に伴う神経細胞障害に対するニルバジピンの保護効果, 第6回長井長義記念シンポジウム, 2005年7月..[著者] ... 姫田 敏樹, 早川 夏美, 籐内 寛子, 佐久間 美央, 荒木 勉 : 虚血性脳疾患におけるインターニューロンの関与とピタバスタチンの効果, 第6回長井長義記念シンポジウム, 2005年7月..[著者] ... 水野 くみ子, 神山 裕子, 門口 直仁, 姫田 敏樹, 荒木 勉 : マウス海馬における老化による免疫組織学的変化の検討, 第6回長井長義記念シンポジウム, 2005年7月..[著者] ... 渡辺 悠, 姫田 敏樹, 門口 直仁, 籐内 寛子, 早川 夏美, 荒木 勉 : MPTP誘発パーキンソン病モデルマウスの線条体におけるS100 の発現変化, 第6回長井長義記念シンポジウム, 2005年7月..[著者] ... Toshiki Himeda, Hayakawa Natsumi, Hiroko Tounai, Mio Sakuma, Kato Hiroyuki and Tsutomu Araki : Alterations of interneurons of the gerbil hippocampus after transient cerebral ischemia: effect of pitavastatin, Neuropsychopharmacology, Vol.30, No.11, 2014-2025, 2005..[著者] ... Toshiki Himeda, Naoto Kadoguchi, Yuko Kamiyama, Hiroyuki Kato, Hitoshi Maegawa and Tsutomu Araki : Neuroprotective effect of arundic acid, an astrocyte-modulating agent, in mouse brain against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity., Neuropharmacology, Vol.50, No.3, 329-344, 2006..[著者] ... 横山 宏典, 渡邉 悠, 高木 翔, 田中 亜紀, 荒木 勉 : MPTP誘発パーキンソン病モデルマウスの黒質神経細胞障害に対するに対するnitric oxide synthase (nNOS)の役割, 第7回長井長義シンポジウム抄録集, 97, 2006年9月..[著者] ... 沖 千絵, 渡邉 悠, 荒木 勉 : MPTP神経毒性に対するArundic acid後投与の効果について, 第7回長井長義シンポジウム抄録集, 103, 2006年9月..[著者] ... 渡邉 悠, 加藤 宏之, 荒木 勉 : パーキンソ病モデルマウスにおけるAngiotensin変換酵素阻害剤の効果, 第7回長井長義記念シンポジウム抄録集, 116, 2006年9月..[著者] ... 藤内 寛子, 早川 夏美, 荒木 勉 : 一過性脳虚血砂ネズミにおける神経栄養因子の発現変化とStainの効果, 第7回長井長義記念シンポジウム抄録集, 136, 2006年9月..[著者] ... 田中 亜紀, 渡邉 悠, 荒木 勉 : 加齢によるICRマウス脳における免疫組織化学的検討, 第7回長井長義記念シンポジウム抄録集, 143, 2006年9月..[著者] ... 早川 夏美, 姫田 敏樹, 荒木 勉 : 一過性脳虚血後の海馬におけるNF-kBおよびp53に関する免疫組織化学的検討とピタバスタチンの効果, 第16回日本医療薬学会年会要旨集, Vol.30-P2-022, 397, 2006年9月..[著者] ... 佐久間 美央, 早川 夏美, 荒木 勉 : 局所脳梗塞ラットモデルにおける基礎的研究, 第45回日本薬学会・日本病院薬剤師会 中国四国支部学術大会要旨集, Vol.28C15-40, 109, 2006年10月..[著者] ... Toshiki Himeda, Y Watanabe, H Tounai, N Hayakawa, H Kato and Tsutomu Araki : Time dependent alterations of co-localization of S100beta and GFAP in the MPTP-treated mice., Journal of Neural Transmission, Vol.113, No.12, 1887-1894, 2006..[著者] ... H Tounai, N Hayakawa, H Kato and Tsutomu Araki : Immunohistochemical study on distribution of NF-κB and p53 in gerbil hippocampus after transient cerebral ischemia: effect of pitavastatin., Metabolic Brain Disease, Vol.22, No.1, 89-104, 2007..[著者] ... Natsumi Hayakawa, Hiroyuki Kato and Tsutomu Araki : Age-related changes of astorocytes, oligodendrocytes and microglia in the mouse hippocampal CA1 sector., Mechanisms of Ageing and Development, Vol.128, No.4, 311-316, 2007..[著者] ... 藤内 寛子, 早川 夏美, 荒木 勉 : 一過性脳虚血後の砂ネズミの海馬におけるHSP70およびユビキチンの発現変化とPitavastatinの効果, 日本薬学会第127年会, Vol.29P1-pm392, 184, 2007年3月..[著者] ... Toshiki Himeda, Hiroko Tounai, Natsumi Hayakawa and Tsutomu Araki : Postischemic alterations of BDNF, NGF, HSP 70 and ubiquitin immunoreactivity in the gerbil hippocampus: pharmacological approach., Cellular and Molecular Neurobiology, Vol.27, No.2, 229-250, 2007..[著者] ... A Tanaka, Y Watanabe, H Kato and Tsutomu Araki : Immunohistochemical changes related to ageing in the mouse hippocampus and subventricular zone, Mechanisms of Ageing and Development, Vol.128, No.4, 303-310, 2007..[著者] ... 東 満美, 日野出 晴美, 柏田 良樹, 吉田 昌裕, 山﨑 尚志, 土屋 浩一郎, 山内 あい子, 柴田 洋文, 新垣 尚捷, 滝口 祥令, 荒木 勉, 吉村 好之, 姫田 敏樹, 石田 竜弘, 辻 大輔, 木原 勝 : 徳島大学薬学部OSCEトライアル実施体制の確立と検証, 第17回 日本医療薬学会年会, 2007年9月..[著者] ... 横山 宏典, 荒木 勉, 渡邉 悠, 高木 翔, 矢野 遼平 : MPTP誘発パーキンソン病モデルマウスに対する各種薬剤の効果, 第46回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会, Vol.10B11-40, 77, 2007年11月..[著者] ... 佐久間 美央, 早川 夏美, 梅田 真洋, 松田 俊輔, 荒木 勉 : 一過性局所脳梗塞ラットの梗塞中心部におけるインターニューロンの変動, --- (一般演題I-1) ---, 第5回フリーラジカルと脳疾患 西日本研究会学術集会, 3, 2007年11月..[著者] ... 高木 翔, 早川 夏美, 木本 浩貴, 荒木 勉 : MPTP誘発パ-キンソン病モデルマウスにおけるoligodendrocyteの変化, --- 『神経疾患とグリアI, ALS, パ-キンソン病』演題16 ---, 第12回グリア研究会, 24, 2007年11月..[著者] ... S Takagi, N Hayakawa, H Kimoto, H Kato and Tsutomu Araki : Damage to oligodendrocytes in the striatum after MPTP neurotoxicity in mice., Journal of Neural Transmission, Vol.114, No.12, 1553-1557, 2007..[著者] ... 佐久間 美央, 早川 夏美, 梅田 真洋, 松田 俊輔, 荒木 勉 : 一過性脳梗塞ラットモデルの梗塞中心部におけるインターニューロンの経時的変動, Phrama Medica, Vol.26, No.6, 125, 2008年..[著者] ... Chie Oki, Yu Watanabe, Hironori Yokoyama, Taiji Shimoda, Hiroyuki Kato and Tsutomu Araki : Delayed Treatment with Arundic Acid Reduces the MPTP-induced Neurotoxicity in Mice., Cellular and Molecular Neurobiology, Vol.28, No.3, 417-430, 2008..[著者] ... 門口 直仁, 高木 翔, 荒木 勉, 監修:鳥澤 保黄 : 創薬支援研究の展望, --- 第8章 実験的パーキンソン病モデル動物を用いた新規薬物療法の開発研究 ---, シーエムシー社, (都市), 2008年2月..[著者] ... M Sakuma, N Hayakawa, H Kato and Tsutomu Araki : Time dependent changes of striatal interneurons after focal cerebral ischemia in rats, Journal of Neural Transmission, Vol.115, No.3, 413-422, 2008..[著者] ... Yu Watanabe, Hiroyuki Kato and Tsutomu Araki : Protective action of neuronal nitric oxide synthase inhibitor in the MPTP mouse model of Parkinson's disease, Metabolic Brain Disease, Vol.23, No.1, 51-69, 2008..[著者] ... Naoto Kadoguchi, Masahiro Umeda, Hiroyuki Kato and Tsutomu Araki : Proteasome inhibitor does not enhance MPTP neurotoxicity in mice, Cellular and Molecular Neurobiology, Vol.28, No.7, 971-979, 2008..[著者] ... Natsumi Hayakawa, Manami Abe, Risa Eto, Hiroyuki Kato and Tsutomu Araki : Age-related changes of NGF, BDNF, parvalbumin and neuronal nitric oxide synthase immunoreactivity in the mouse hippocampal CA1 sector., Metabolic Brain Disease, Vol.23, No.2, 199-211, 2008..[著者] ... 横山 宏典, 矢野 遼平, 高木 翔, 加藤 宏之, 荒木 勉 : MPTP誘発パーキンソン病モデルマウスに対する各種薬剤の神経細胞保護効果に関す る検討, 第16回カテコールアミンと神経変性疾患研究会要旨集, 13, 2008年4月..[著者] ... Hironori Yokoyama, Sho Takagi, Yu Watanabe, Hiroyuki Kato and Tsutomu Araki : Role of reactive nitrogen and reactive oxygen species against MPTP neurotoxicity in mice, Journal of Neural Transmission, Vol.115, No.6, 831-842, 2008..[著者] ... Naoto Kadoguchi, Hiroki Kimoto, Ryohei Yano, Hiroyuki Kato and Tsutomu Araki : Failure of acute administration with proteasome inhibitor to provide a model of Parkinson's disease in mice., Metabolic Brain Disease, Vol.23, No.2, 147-154, 2008..[著者] ... 横山 宏典, 矢野 遼平, 高木 翔, 黒岩 勇人, 加藤 宏之, 荒木 勉 : MPTP誘発パーキンソン病モデルマウスに対する各種薬剤の神経細胞保護効果に関する検討, 脳21, Vol.11, No.3, 381, 2008年..[著者] ... Hironori Yokoyama, Ryohei Yano, Eriko Aoki, Hiroyuki Kato and Tsutomu Araki : Comparative pharmacological study of free radical scavenger, nitric oxide synthase inhibitor, nitric oxide synthase activator and cyclooxygenase inhibitor against MPTP neurotoxicity in mice, Metabolic Brain Disease, Vol.23, No.3, 335-349, 2008..[著者] ... Natsumi Hayakawa, Hironori Yokoyama, Hiroyuki Kato and Tsutomu Araki : Age-related alterations of oxidative stress markers in the mouse hippocampal CA1 sector, Experimental and Molecular Pathology, Vol.85, No.2, 135-140, 2008..[著者] ... Hironori Yokoyama, Hayato Kuroiwa, Ryohei Yano and Tsutomu Araki : Targeting reactive oxygen species, reactive nitrogen species and inflammation in MPTP neurotoxicity and Parkinson's disease, Neurological Sciences, Vol.29, No.5, 293-301, 2008..[著者] ... 横山 宏典, 矢野 遼平, 高木 翔, 大久保 雅則, 黒岩 勇人, 荒木 勉 : MPTP神経毒性に対する各種薬剤の保護効果の検討, 第47回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会 講演要旨集, 103, 2008年11月..[著者] ... 大久保 雅則, 横山 宏典, 高木 翔, 矢野 遼平, 押川 拓矢, 荒木 勉 : MPTP神経毒性に対するEstrogenの効果に関する検討, 第47回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会 講演要旨集, 102, 2008年11月..[著者] ... Risa Eto, Manami Abe, Natsumi Hayakawa, Hiroyuki Kato and Tsutomu Araki : Age-related changes of calcineurin and Akt1/protein kinase Balpha (Akt1/PKBalpha) immunoreactivity in the mouse hippocampal CA1 sector: an immunohistochemical study, Metabolic Brain Disease, Vol.23, No.4, 399-409, 2008..[著者] ... Masanori Ookubo, Hironori Yokoyama, Sho Takagi, Hiroyuki Kato and Tsutomu Araki : Effects of estrogens on striatal damage after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in male and female mice, Molecular and Cellular Endocrinology, Vol.296, No.1-2, 87-93, 2008..[著者] ... 松田 俊輔, 梅田 真洋, 加藤 宏之, 荒木 勉 : 一過性脳虚血ラットにおける酸化ストレス及びアポトーシスマーカーの変化, 第2回次世代を担う若手医療薬科学シンポジウム -科学的基盤に立脚した医療薬学研究の推進に向けて- 薬学雑誌 講演要旨集, 43, 2008年12月..[著者] ... 矢野 遼平, 横山 宏典, 黒岩 勇人, 加藤 宏之, 荒木 勉 : マウスにおけるMPTP神経毒性に対するZonisamideの保護効果, 第2回次世代を担う若手医療薬科学シンポジウム -科学的基盤に立脚した医療薬学研究の推進に向けて- 薬学雑誌 講演要旨集, 46, 2008年12月..[著者] ... H Yokoyama, t Tsukada, H Uchida and Tsutomu Araki : Novel therapies in an MPTP model of Parkinson's disease, Current Trends in Neurology, Vol.3, 23-31, (month)2009..[著者] ... Eriko Aoki, Ryohei Yano, Hironori Yokoyama, Hiroyuki Kato and Tsutomu Araki : Role of nuclear transcription factor kappa B (NF-kappaB) for MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahyropyridine)-induced apoptosis in nigral neurons of mice, Experimental and Molecular Pathology, Vol.86, No.1, 57-64, 2009..[著者] ... 荒木 靖子, 荒木 勉, 今井 潤 : カッツング薬理学 原書10版, --- X 特殊な題目 66章 医薬品の適正使用と処方箋の書き方の部 pp1174-1183 ---, 丸善 株式会社, 東京, 2009年3月..[著者] ... S Matsuda, M Umeda, H Uchida, H Kato and Tsutomu Araki : Alterations of oxidative stress markers and apoptosis markers in the striatum after transient focal cerebral ischemia in rats., Journal of Neural Transmission, Vol.116, No.4, 395-404, 2009..[著者] ... 横山 宏典, 矢野 遼平, 塚田 竜矢, 佐々木 妙子, 加藤 宏之, 荒木 勉 : MPTP誘発パーキンソン病モデルマウスに対するゾニサミドの神経細胞保護効果に関する基礎的検討, 第17回カテコールアミンと神経変性疾患研究会 要旨集, 11, 2009年4月..[著者] ... Shunsuke Matsuda, Masahiro Umeda, Hiroyuki Kato and Tsutomu Araki : Glial Damage After Transient Focal Cerebral Ischemia in Rats, Journal of Molecular Neuroscience : MN, Vol.38, No.2, 220-226, 2009..[著者] ... Takuya Oshikawa, Hayato Kuroiwa, Ryohei Yano, Hironori Yokoyama, Naoto Kadoguchi, Hiroyuki Kato and Tsutomu Araki : Systemic administration of proteasome inhibitor protects against MPTP neurotoxicity in mice, Cellular and Molecular Neurobiology, Vol.29, No.5, 769-777, 2009..[著者] ... 横山 宏典, 矢野 遼平, 塚田 竜矢, 佐々木 妙子, 加藤 宏之, 荒木 勉 : MPTP誘発パーキンソン病モデルマウスに対するゾニサミドの神経細胞保護効果に関する基礎的研究, 脳21, Vol.12, No.3, 114, 2009年..[著者] ... Ryohei Yano, Hironori Yokoyama, Hayato Kuroiwa, Hiroyuki Kato and Tsutomu Araki : A Novel Anti-Parkinsonian Agent, Zonisamide, Attenuates MPTP-Induced Neurotoxicity in Mice., Journal of Molecular Neuroscience : MN, Vol.39, No.1-2, 211-219, 2009..[著者] ... Masanori Ookubo, Hironori Yokoyama, Hiroyuki Kato and Tsutomu Araki : Gender differences on MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in C57BL/6 mice., Molecular and Cellular Endocrinology, Vol.311, No.1-2, 62-68, 2009..[著者] ... 塚田 竜矢, 横山 宏典, 佐々木 妙子, 荒木 勉 : MPTP誘発パーキンソン病モデルマウスに対するゾニサミドの治療効果に関する基礎的検討, 第48回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会 講演要旨集, 100, 2009年11月..[著者] ... 内田 裕人, 松田 俊輔, 梅田 真洋, 荒木 勉 : 一過性脳虚血ラットの慢性期における黒質の変化, 第48回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会 講演要旨集, 101, 2009年11月..[著者] ... 黒岩 勇人, 横山 宏典, 荒木 勉 : 種々の投与スケジュールを用いたMPTP誘発パーキンソン病モデルマウス作成に関する検討, 第48回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会 講演要旨集, 102, 2009年11月..[著者] ... 横山 宏典, 黒岩 勇人, 塚田 竜矢, 内田 裕人, 荒木 勉 : MPTP神経毒性に対するPARP阻害剤の神経細胞保護効果に関する検討, 第48回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会 講演要旨集, 102, 2009年11月..[著者] ... 松田 俊輔, 梅田 真洋, 内田 裕人, 荒木 勉 : 一過性脳虚血ラットにおけるグリア細胞障害に関する検討, 第48回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会 講演要旨集, 103, 2009年11月..[著者] ... 木本 浩貴, 衛藤 里沙, 阿部 真己, 荒木 勉 : 発達期マウスの海馬におけるグリア細胞に対する検討, 第48回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会 講演要旨集, 110, 2009年11月..[著者] ... 阿部 真己, 木本 浩貴, 衛藤 里沙, 佐々木 妙子, 荒木 勉 : 発達期マウスの黒質における基礎的解析, 第48回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会 講演要旨集, 110, 2009年11月..[著者] ... Hiroki Kimoto, Risa Eto, Manami Abe, Hiroyuki Kato and Tsutomu Araki : Alterations of Glial Cells in the Mouse Hippocampus During Postnatal Development, Cellular and Molecular Neurobiology, Vol.29, No.8, 1181-1189, 2009..[著者] ... Keizo Takao, Koichi Tanda, Kenji Nakamura, Jiro Kasahara, Kazuki Nakao, Motoya Katsuki, Kazuo Nakanishi, Nobuyuki Yamasaki, Keiko Toyama, Minami Adachi, Masahiro Umeda, Tsutomu Araki, Kohji Fukunaga, Hisatake Kondo, Hiroyuki Sakagami and Tsuyoshi Miyakawa : Comprehensive behavioral analysis of calcium/calmodulin-dependent protein kinase IV knockout mice., PLoS ONE, Vol.5, No.3, (頁), 2010..[著者] ... Eriko Aoki, Hironori Yokoyama, Hiroki Kimoto, Ryohei Yano, Hiroyuki Kato and Tsutomu Araki : Chronic Administration with Rotenone does not Enhance MPTP Neurotoxicity in C57BL/6 Mice., Journal of Molecular Neuroscience : MN, Vol.41, No.1, 17-24, 2010..[著者] ... 黒岩 勇人, 横山 宏典, 塚田 竜矢, 笠原 二郎, 荒木 勉 : MPTP誘発パーキンソン病モデルマウスに対するPARP阻害剤及びPPAR作動薬の神経細胞保護効果に関する研究ーzonisamideとの比較研究, 第18回カテコールアミンと神経変性疾患研究会 要旨集 pp 11, (巻), (号), (頁), 2010年4月..[著者] ... Hironori Yokoyama, Ryohei Yano, Hayato Kuroiwa, Tatsuya Tsukada, Hiroto Uchida, Hiroyuki Kato, Jiro Kasahara and Tsutomu Araki : Therapeutic effect of a novel anti-parkinsonian agent zonisamide against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)neurotoxicity in mice., Metabolic Brain Disease, Vol.25, No.2, 135-143, 2010..[著者] ... Hironori Yokoyama, Hayato Kuroiwa, Tatsuya Tsukada, Hiroto Uchida, Hiroyuki Kato and Tsutomu Araki : Poly(ADP-ribose)polymerase inhibitor can attenuate the neuronal death after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice, Journal of Neuroscience Research, Vol.88, No.7, 1522-1536, 2010..[著者] ... 笠原 二郎, 大村 幸司, 安達 みなみ, 福永 浩司, 荒木 勉 : マウス大脳皮質におけるセロトニンを介したCREBリン酸化反応, 第51回日本生化学会中国・四国支部例会, 59, 2010年5月..[著者] ... Hayato Kuroiwa, Hironori Yokoyama, Hiroki Kimoto, Hiroyuki Kato and Tsutomu Araki : Biochemical alterations of the striatum in an MPTP-treated mouse model of Parkinson's disease., Metabolic Brain Disease, Vol.25, No.2, 177-183, 2010..[著者] ... H Uchida, H Yokoyama, H Kimoto, H Kato and Tsutomu Araki : Long-term changes in the ipsilateral substantia nigra after transient focal cerebral ischaemia in rats, International Journal of Experimental Pathology, Vol.91, No.3, 256-266, 2010..[著者] ... Hironori Yokoyama, Tatsuya Tsukada, Hiroto Uchida and Tsutomu Araki : Novel therapies in an MPTP model of Parkinson's disease, Current Trends in Neurology, Vol.3, (号), 23-31, July 2010..[著者] ... 黒岩 勇人, 横山 宏典, 内田 裕人, 塚田 竜矢, 加藤 宏之, 笠原 二郎, 荒木 勉 : MPTP誘発パーキンソン病モデルマウスに対するPARP阻害薬およびPPAR作動薬の神経細胞保護効果に関する研究ーzonisamideとの比較研究ー, 脳21, Vol.13, No.3, 116-116-1161-16, 2010年..[著者] ... 笠原 二郎, 安達 みなみ, 大村 幸司, 福永 浩司, 荒木 勉 : マウス大脳皮質ニューロンにおいてセロトニンはCREBリン酸化反応を惹起する, 第117回日本薬理学会近畿部会プログラム·要旨集, (巻), (号), 11-11, 2010年7月..[著者] ... 荒木 勉, 黒岩 勇人, 横山 宏典, 門口 直仁, 笠原 二郎 : MPTP誘発パーキンソン病モデルマウスに対するプロテアソーム阻害剤の神経保護効果, 第117回日本薬理学会近畿部会プログラム·要旨集, (巻), (号), 13-13, 2010年7月..[著者] ... H Uchida, Y Fujita, M Matsueda, M Umeda, S Matsuda, H Kato, Jiro Kasahara and Tsutomu Araki : Damage to Neurons and Oligodendrocytes in the Hippocampal CA1 Sector after Transient Focal Ischemia in Rats, Cellular and Molecular Neurobiology, Vol.30, No.7, 1125-1134, 2010..[著者] ... M Abe, H Kimoto, R Eto, T Sasaki, H Kato, Jiro Kasahara and Tsutomu Araki : Postnatal Development of Neurons, Interneurons and Glial Cells in the Substantia Nigra of Mice, Cellular and Molecular Neurobiology, Vol.30, No.6, 917-928, 2010..[著者] ... R Eto, M Abe, H Kimoto, E Imaoka, H Kato, Jiro Kasahara and Tsutomu Araki : Alterations of interneurons in the striatum and frontal cortex of mice during postnatal development, International Journal of Developmental Neuroscience, Vol.28, No.5, 359-370, 2010..[著者] ... Jiro Kasahara, Ohmura Kohji, Adachi Minami, Fukunaga Kohji and Tsutomu Araki : Serotonin (5-HT)-induced CREB phosphorylation mediated by calcium/calmodulin-dependent protein kinase IV (CaMKIV) and extracellular signal-regulated protein kinase (ERK) in cultured cortical neurons of mice, Neuro2010, Vol.49, No.2,3, 527, Sep. 2010..[著者] ... Minami Adachi, Manami Abe, Taeko Sasaki, Hiroyuki Kato, Jiro Kasahara and Tsutomu Araki : Role of inducible or neuronal nitric oxide synthase in neurogenesis of the dentate gyrus in aged mice, Metabolic Brain Disease, Vol.25, 419-424, 2010..[著者] ... Jiro Kasahara, Adachi Minami, Ohmura Koji, Fukunaga Kohji and Tsutomu Araki : Serotonin (5-HT)-induced CREB phosphorylation in the cortical neurons of mice, Soc. Abst. Neurosci., Vol.40, 741-18, (都市), Nov. 2010..[著者] ... Hironori Yokoyama, Hiroto Uchida, Hayato Kuroiwa, Jiro Kasahara and Tsutomu Araki : Role of glial cells in neurotoxin-induced animal models of Parkinson's disease., Neurological Sciences, Vol.32, No.1, 1-7, 2011..[著者] ... Hironori Yokoyama, Hayato Kuroiwa, Jiro Kasahara and Tsutomu Araki : Neuropharmacological approach against MPTP (1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine)-induced mouse model of Parkinson's disease., Acta Neurobiologiae Experimentalis, Vol.71, No.2, 269-280, 2011..[著者] ... Emanuel Abraham, Mukesh Jewariya, Tetsuo Iwata, Tsutomu Araki and Takeshi Yasui : Fast 3D computed tomography using intense terahertz pulses, 38th International Conference on Infrared, Millimeter, and Terahertz Waves(IRMMW-THz2013), Mainz, Germany, Sep. 2013..[著者] ... Yuji Tanaka, Eiji Hase, Shuichiro Fukushima, Yuki Ogura, Toyonobu Yamashita, Tetsuji Hirao, Tsutomu Araki and Takeshi Yasui : Motion-artifact-robust, polarization-resolved second-harmonic-generation microscopy based on rapid polarization switching with electro-optic Pockells cell and its application to in vivo visualization of collagen fiber orientation in human facial skin, Biomedical Optics Express, Vol.5, No.4, 1099-1113, 2014..[著者] ... 水口 達也, 胡 国庆, 南川 丈夫, 荒木 勉, 郑 铮, 安井 武史 : デュアル光コム分光のための2波長ファイバー光コム光源, レーザー学会学術講演会第37回年次大会, 2017年1月..[著者] ...
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