OWN= | 大東 いずみ ([徳島大学.先端酵素学研究所.重点研究部門]) |
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有効な情報: 78件 + 無効な情報: 7件 = 全ての情報: 85件
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Takeshi Nitta, Mariam Nasreen, Takafumi Seike, Atsushi Goji, Izumi Ohigashi, Tadaaki Miyazaki, Tsutomu Ohta, Masamoto Kanno and Yousuke Takahama : IAN family critically regulates survival and development of T lymphocytes, PLoS Biology, Vol.4, No.4, e103-e115, 2006. | ... | |||||
Yu Hikosaka, Takeshi Nitta, Izumi Ohigashi, Kouta Yano, Naozumi Ishimaru, Yoshio Hayashi, Mitsuru Matsumoto, Koichi Matsuo, Josef M Penninger, Hiroshi Takayanagi, Yoshifumi Yokota, Hisakata Yamada, Yasunobu Yoshikai, Jun-ichiro Inoue, Taishin Akiyama and Yousuke Takahama : The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator., Immunity, Vol.29, No.3, 438-450, 2008. | ... | |||||
Taishin Akiyama, Yusuke Shimo, Hiromi Yanai, Junwen Qin, Daisuke Ohshima, Yuya Maruyama, Yukiko Asaumi, Juli Kitazawa, Hiroshi Takayanagi, Josef Penninger, Mitsuru Matsumoto, Takeshi Nitta, Yousuke Takahama and Jun-ichiro Inoue : The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance., Immunity, Vol.29, No.3, 423-437, 2008. | ... | |||||
DA Sultana, Shuhei Tomita, M Hamada, Y Iwanaga, Y Kitahama, NV Khang, S Hirai, Izumi Ohigashi, S Nitta, T Amagai, S Takahashi and Yousuke Takahama : Gene expression profile of the third pharyngeal pouch reveals role of mesenchymal MafB in embryonic thymus development, Blood, Vol.113, No.13, 2976-2987, 2009. | ... | |||||
Izumi Ohigashi, Yuki Yamasaki, Tsukasa Hirashima and Yousuke Takahama : Identification of the Transgenic Integration Site in Immunodeficient tgϵ26 Human CD3ϵ Transgenic Mice, PLoS ONE, Vol.5, No.12, e14391, 2010. | ... | |||||
Yu Lei, Adiratna Mat Ripen, Naozumi Ishimaru, Izumi Ohigashi, Takashi Nagasawa, Lukas T. Jeker, Michael R. Bösl, Georg A. Holländer, Yoshio Hayashi, Rene Waal de Malefyt, Takeshi Nitta and Yousuke Takahama : Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development, The Journal of Experimental Medicine, Vol.208, No.2, 383-394, 2011. | ... | |||||
Kensuke Takada, Izumi Ohigashi, Michiyuki Kasai, Hiroshi Nakase and Yousuke Takahama : Development and function of cortical thymic epithelial cells., Current Topics in Microbiology and Immunology, Vol.373, 1-17, 2014. | ... | |||||
Myn Uddin, 大東 いずみ, 高浜 洋介 : Seeking transcriptional mechanisms for regulation of b5t expression, 第14回 四国免疫フォーラム, 2015年6月. | ... | |||||
Izumi Ohigashi, Saulius Zuklys, Mie Sakata, Carlos E. Mayer, Yoko Hamazaki, Nagahiro Minato, Georg A Hollander and Yousuke Takahama : Adult thymic medullary epithelium is maintained and regenerated by lineage-restricted cells rather than bipotent progenitors, Cell Reports, Vol.13, No.7, 1432-1443, 2015. | ... | |||||
Izumi Ohigashi and Yousuke Takahama : Differentiation potential of b5t+ thymic epithelial progenitors, 第44回日本免疫学会総会学術集会, Nov. 2015. | ... | |||||
Mina Kozai, Izumi Ohigashi and Yousuke Takahama : Defective self-tolerance in CCL21-deficient mice, 第44回日本免疫学会総会学術集会, Nov. 2015. | ... | |||||
近藤 博之, 大東 いずみ, 高浜 洋介 : 胸腺皮質上皮細胞で高発現される機能未知新規遺伝子の研究, 2015感染免疫クラスター・ミニリトリート, 2015年11月. | ... | |||||
Izumi Ohigashi and Yousuke Takahama : Flow Cytometry Analysis of Thymic Epithelial Cells and Their Subpopulations, Methods in Molecular Biology, Vol.1323, 65-73, 2016. | ... | |||||
Izumi Ohigashi and Yousuke Takahama : Thymocyte-mTEC cross talk for self-tolerance in T cells, Encyclopedia of Immunology, Vol.1, 263-267, 2016. | ... | |||||
大東 いずみ, 高浜 洋介 : 髄質上皮細胞の維持と再生におけるb5t陽性前駆細胞の寄与, 第35回胸腺研究会, 2016年2月. | ... | |||||
Izumi Ohigashi and Yousuke Takahama : Foxn1-binding cis-regulatory element required for optimal CD8+ T cell production in the thymus, The Fifth Bizan Immunology symposium, 徳島県徳島市, March 2016. | ... | |||||
CE Mayer, S Zuklys, S Zhanybekova, Izumi Ohigashi, HY Teh, SN Sansom, N Shikama-Dorn, K Hafen, IC Macaulay, ME Deadman, CP Ponting, Yousuke Takahama and GA Hollander : Dynamic spatio-temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla, European Journal of Immunology, Vol.46, No.4, 846-856, 2016. | ... | |||||
Izumi Ohigashi and Yousuke Takahama : Thymocyte-mTEC cross talk for self-tolerance in T cells., Elsevier, (都市), April 2016. | ... | |||||
Izumi Ohigashi, Mina Kozai and Yousuke Takahama : Development and developmental potential of cortical thymic epithelial cells, Immunological Reviews, Vol.271, No.1, 10-22, 2016. | ... | |||||
Myn Uddin, 大東 いずみ, 高浜 洋介 : Foxn1-binding cis-regulatory element for optimal CD8+ T cell production in the thymus, 第26回 Kyoto T cell Conference, 2016年5月. | ... | |||||
香西 美奈, 大東 いずみ, 高浜 洋介 : CCL21, 第15回四国免疫フォーラム, 2016年6月. | ... | |||||
藤森 さゆ美, 大東 いずみ, 竹本 龍也, 高浜 洋介, 高田 慎治 : マウス胸腺上皮細胞におけるWnt/β-cateninシグナル経路の時空間的活性化, 第39回日本分子生物学会年会, 2016年12月. | ... | |||||
大東 いずみ, 竹本 龍也, 高浜 洋介 : 胸腺におけるCD8+ T細胞生成を制御するFoxn1結合シス制御領域の同定, 第39回日本分子生物学会年会, 2016年12月. | ... | |||||
Uddin Myn, Izumi Ohigashi and Yousuke Takahama : Foxn1-binding cis-regulatory element required for optimal CD8+ T cell production in the thymus, 第46回日本免疫学会学術集会, Dec. 2016. | ... | |||||
Izumi Ohigashi, Uddin Myn, Tatsuya Takemoto and Yousuke Takahama : Foxn1-binding cis-regulatory element required for optimal CD8+ T cell production in the thymus, 11th International Symposium of The Institute Network Frontiers in Biomedical Sciences, (都市), Jan. 2017. | ... | |||||
Kozai Mina, Izumi Ohigashi and Yousuke Takahama : CCL21 regulates T-cell self-tolerance in thymic medulla, 11th International Symposium of The Institute Network Frontiers in Biomedical Sciences, (都市), Jan. 2017. | ... | |||||
大東 いずみ, 高浜 洋介 : 胸腺髄質上皮細胞の再生におけるβ5t陽性上皮前駆細胞の寄与, 第36回胸腺研究会, 2017年2月. | ... | |||||
Sayumi Fujimori, Izumi Ohigashi, Tatsuya Takemoto, Yousuke Takahama and Takada Shinji : Activation of Wnt/β-catenin signaling in thymic epithelial progenitors, 7th International Workshop of Kyoto T Cell Conference, Kyoto, March 2017. | ... | |||||
Izumi Ohigashi, Ohte Yuki, Setoh Kazuya, Matsuda Fumihiko, Murata Shigeo and Yousuke Takahama : A human Psmb11 polymorphism affects molecular processing of thymoproteasome and thymic production of CD8+ T cells, 7th International Workshop of Kyoto T Cell Conference, (都市), March 2017. | ... | |||||
Kondo Hiroyuki, Izumi Ohigashi, Kozai Mina, Kubo Yuki, Katakai Tomoya, Luther A. Sanjiv and Yousuke Takahama : Essential role of CCL21 in establishment of central self-tolerance in T cells, 7th International Workshop of Kyoto T Cell Conference, (都市), March 2017. | ... | |||||
Uddin Myn, Izumi Ohigashi and Yousuke Takahama : Foxn1-b5t transcriptional axis controls CD8+ T-cell production in the thymus, IMMUNOLOGY 2017, AAI Annual Meeting, (都市), May 2017. | ... | |||||
Izumi Ohigashi, Yuki Ohte, Kazuya Setoh, Hiroshi Nakase, Akiko Maekawa, Hiroshi Kiyonari, Yoko Hamazaki, Miho Sekai, Tetsuo Sudo, Yasuharu Tabara, Hiromi Sawai, Yosuke Omae, Rika Yuliwulandari, Yasuhito Tanaka, Masashi Mizokami, Hiroshi Inoue, Masanori Kasahara, Nagahiro Minato, Katsushi Tokunaga, Keiji Tanaka, Fumihiko Matsuda, Shigeo Murata and Yousuke Takahama : A human PSMB11 variant affects thymoproteasome processing and CD8+ T cell production, JCI Insight, Vol.2, No.10, 2017. | ... | |||||
Yousuke Takahama, Izumi Ohigashi, Song Baik and Graham Anderson : Generation of diversity in thymic epithelial cells, Nature Reviews. Immunology, Vol.17, No.5, 295-305, May 2017. | ... | |||||
近藤 博之, 大東 いずみ, 高浜 洋介 : CCL21Ser欠損マウスにおけるT細胞異常, 第16回四国免疫フォーラム, 2017年6月. | ... | |||||
Mina Kozai, Yuki Kubo, Tomoya Katakai, Hiroyuki Kondo, Hiroshi Kiyonari, Karin Schaeuble, Sanjiv A. Luther, Naozumi Ishimaru, Izumi Ohigashi and Yousuke Takahama : Essential role of CCL21 in establishment of central self-tolerance in T cells, The Journal of Experimental Medicine, Vol.214, No.7, 1925-1935, 2017. | ... | |||||
藤森 さゆ美, 大東 いずみ, 竹本 龍也, 高田 慎治, 高浜 洋介 : マウス胸腺皮質上皮細胞亜集団におけるWnt/β-cateninシグナル経路の活性化, 第40回日本分子生物学会年会, 2017年12月. | ... | |||||
大東 いずみ, 石丸 直澄, Katakai Tomoya, 高浜 洋介 : T細胞の自己寛容性確立におけるCCL21の役割, 第40回 日本分子生物学会年会, 2017年12月. | ... | |||||
大東 いずみ, 高浜 洋介 : T細胞の自己寛容性確立におけるCCL21の役割, 第37回 日本胸腺研究会, 2018年2月. | ... | |||||
松井 尚子, 大東 いずみ, 山本 遥平, 中川 英刀, 近藤 和也, 高浜 洋介 : ヒト胸腺を用いた胸腺上皮細胞の解析, 第37回日本胸腺研究会, 2018年2月. | ... | |||||
Izumi Ohigashi and Yousuke Takahama : Human PSMB11 polymorphisms that affect thymoproteasome processing and CD8+ T cell generation, 8th THYMOZ, (都市), March 2018. | ... | |||||
近藤 博之, 高浜 洋介, 大東 いずみ : 胸腺皮質上皮細胞で高発現する新規分子の機能解析, 第28回 Kyoto T cell Conference, 2018年6月. | ... | |||||
UMME KHANOM SHAHINA, 近藤 健太, 高田 健介, 大東 いずみ, 高浜 洋介 : Peptide-induced positive selection of CD8+ T cells in vivo, 第17回 四国免疫フォーラム, 2018年6月. | ... | |||||
Emilie J. Cosway, Izumi Ohigashi, Karin Schauble, Sonia M. Parnell, William E. Jenkinson, Sanjiv Luther, Yousuke Takahama and Graham Anderson : Formation of the intrathymic dendritic cell pool requires CCL21-mediated recruitment of CCR7+ progenitors to the thymus, The Journal of Immunology, Vol.201, No.2, 516-523, 2018. | ... | |||||
A Takeuchi, M Ozawa, Y Kanda, M Kozai, Izumi Ohigashi, Y Kurosawa, MA Rahman, T Kawamura, Y Shichida, E Umemoto, M Miyasaka, B Ludewig, Y Takahama, T Nagasawa and T Katakai : A Distinct Subset of Fibroblastic Stromal Cells Constitutes the Cortex-Medulla Boundary Subcompartment of the Lymph Node, Frontiers in Immunology, Vol.9, 2196, 2018. | ... | |||||
近藤 博之, 松村 貴史, 小迫 英尊, 伊川 正人, 高浜 洋介, 大東 いずみ : プロテアソームに会合する新規分子PITHD1の機能解析, 第41回日本分子生物学会年会, 2018年11月. | ... | |||||
Yousuke Takahama, Izumi Ohigashi, Shigeo Murata and Keiji Tanaka : Thymoproteasome and peptidic self, Immunogenetics, Vol.71, No.3, 217-221, 2019. | ... | |||||
Kenta Kondou, Izumi Ohigashi and Y Takahama : Thymus machinery for T-cell selection, International Immunology, Vol.31, No.3, 119-125, 2019. | ... | |||||
大東 いずみ, 近藤 健太, 高浜 洋介 : 免疫生物学(原書第9版) 監訳 笹月健彦,吉開泰信, 南江堂, 東京都, 2019年3月. | ... | |||||
Izumi Ohigashi, Yu Tanaka, Kenta Kondou, Sayumi Fujimori, Amy C. Palin, Hiroyuki Kondo, Hidetaka Kosako and Yousuke Takahama : Trans-omics impact of thymoproteasome in cortical thymic epithelial cells, ThymE: T cell and thymus biology, (都市), May 2019. | ... | |||||
Sayumi Fujimori, Izumi Ohigashi, Takahama Yousuke and Takada Shinji : Role of β-catenin in thymic epithelial progenies of β5t positive progenitors, ThymE: T cell and thymus biology, (都市), May 2019. | ... | |||||
大東 いずみ, 高浜 洋介 : 胸腺上皮細胞のオミクスプロファイリング, 第29回 Kyoto T cell conference, 2019年6月. | ... | |||||
村松 直美, 大東 いずみ, 高浜 洋介 : CD8T細胞の正の選択におけるペプチドスイッチ仮説の検証, 第29回 Kyoto T cell conference, 2019年6月. | ... | |||||
藤森 さゆ美, 大東 いずみ, 高田 慎治, 高浜 洋介 : 胸腺上皮細胞特異的なWnt/β-cateninシグナル経路活性制御の影響, 第18回 四国免疫フォーラム, 2019年6月. | ... | |||||
Shahina Umme Khanom, Izumi Ohigashi, Sayumi Fujimori, Kenta Kondou, Kensuke Takada and Yousuke Takahama : TCR affinity for in vivo peptide-induced thymic positive selection fine-tunes TCR responsiveness of peripheral CD8+ T cells, The Journal of Immunology, Vol.203, No.4, 881-887, 2019. | ... | |||||
Izumi Ohigashi : Trnas-omics profiling of thymic epithelial cells, The 4th Symposium of the inter-university research network for trans-omics medicine, (都市), Nov. 2019. | ... | |||||
Jennifer E. Cowan, Justin Malin, Yongge Zhao, Mina O. Seedhom, Christelle Harly, Izumi Ohigashi, Michael Kelly, Yousuke Takahama, Jonathan W. Yewdell, Maggie Cam and Avinash Bhandoola : Myc controls a distinct transcriptional program in fetal thymic epithelial cells that determines thymus growth, Nature Communications, Vol.10, No.1, 5498, 2019. | ... | |||||
近藤 博之, 松村 貴史, 小迫 英尊, 伊川 正人, 高浜 洋介, 大東 いずみ : 新規プロテアソーム会合因子PITHD1は精子形成を制御する, 第42回日本分子生物学学会年会, 2019年12月. | ... | |||||
大東 いずみ, 小迫 英尊, 高浜 洋介 : 胸腺上皮細胞のオミクスプロファイリング, 第42回日本分子生物学会年会, 2019年12月. | ... | |||||
Hiroyuki Kondo, Takafumi Matsumura, Mari Kaneko, Kenichi Inoue, Hidetaka Kosako, Masahito Ikawa, Yousuke Takahama and Izumi Ohigashi : PITHD1 is a proteasome-interacting protein essential for male fertilization, The Journal of Biological Chemistry, Vol.295, No.6, 1658-1672, 2020. | ... | |||||
B Lucas, AJ White, EJ Cosway, SM Parnell, KD James, ND Jones, Izumi Ohigashi, Yousuke Takahama, WE Jenkinson and G Anderson : Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells, Nature Communications, Vol.11, No.1, 2020. | ... | |||||
JE Cowan, Yousuke Takahama, A Bhandoola and Izumi Ohigashi : Postnatal involution and counter-involution of the thymus. Frontiers in Immunology, Frontiers in Immunology, Vol.11, No.897, 2020. | ... | |||||
M Lachén-Montes, N Mendizuri, K Ausín, A Pérez-Mediavilla, M Azkargorta, I Iloro, F Elortza, Hiroyuki Kondo, Izumi Ohigashi, I Ferrer, R la Torre de, P Robledo, J Fernández-Irigoyen and E Santamaría : Smelling the Dark Proteome: Functional Characterization of PITH Domain-Containing Protein 1 (C1orf128) in Olfactory Metabolism, Journal of Proteome Research, Vol.19, No.12, 4826-4843, 2020. | ... | |||||
KD James, DF Legler, V Purvanov, Izumi Ohigashi, Yousuke Takahama, SM Parnell, AJ White, WE Jenkinson and G Anderson : Medullary stromal cells synergize their production and capture of CCL21 for T-cell emigration from neonatal mouse thymus, Blood Advances, Vol.5, No.1, 99-112, 2021. | ... | |||||
Ferreirinha Pedro, Ribeiro Camila, Junko Morimoto, Landry J M Jonathan, Minoru Matsumoto, Meireles Catarina, White J Andrea, Izumi Ohigashi, Araújo Leonor, Benes Vladimir, Yousuke Takahama, Anderson Graham, Mitsuru Matsumoto and Alves L Nuno : A novel method to identify Post-Aire stages of medullary thymic epithelial cell differentiation, European Journal of Immunology, Vol.51, No.2, 311-318, 2021. | ... | |||||
Melina Frantzeskakis, Yousuke Takahama and Izumi Ohigashi : The role of proteasomes in the thymus, Frontiers in Immunology, Vol.12, No.646209, March 2021. | ... | |||||
Izumi Ohigashi and Yousuke Takahama : Thymoproteasome optimizes positive selection of CD8+ T cells without contribution of negative selection, Advances in Immunology, Vol.149, 1-23, May 2021. | ... | |||||
Izumi Ohigashi and Yousuke Takahama : Specific impact of β5t on proteasome subunit composition in cortical thymic epithelial cells, Cell Reports, Vol.36, No.10, 109657, 2021. | ... | |||||
(種別) : Izumi Ohigashi, Mami Matsuda-Lennikov and Yousuke Takahama : Peptides for T cell selection in the thymus., Peptides, Vol.146, (号), 170671, (発行所), (都市), Oct. 2021. | ... | |||||
大東 いずみ : 胸腺プロテアソームとTCRレパトア選択, 臨床免疫·アレルギー科, Vol.76, No.5, 567-572, 2021年11月. | ... | |||||
Y Zhang, L Garcia-Ibanez, C Ulbricht, LSC Lok, JA Pike, J Mueller-Winkler, TW Dennison, JR Ferdinand, CJM Burnett, JC Yam-Puc, L Zhang, RM Alfaro, Yousuke Takahama, Izumi Ohigashi, G Brown, T Kurosaki, VLJ Tybulewicz, A Rot, AE Hauser, MR Clatworthy and KM Toellner : Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift, Nature Communications, Vol.13, No.1, 2460, 2022. | ... | |||||
M Matsuda-Lennikov, Izumi Ohigashi and Yousuke Takahama : Tissue-specific proteasomes in generation of MHC class I peptides and CD8+ T cells, Current Opinion in Immunology, Vol.77, (号), 102217, Aug. 2022. | ... | |||||
Izumi Ohigashi, M Matsuda-Lennikov and Yousuke Takahama : Large-scale isolation of mouse thymic epithelial cells, (発行所), (都市), Nov. 2022. | ... | |||||
大東 いずみ, Frantzeskakis Melina, 高浜 洋介 : 胸腺プロテアソームは負の選択非依存的にCD8+T細胞の至適産生を制御する, 第45回日本分子生物学会年会, 2022年11月. | ... | |||||
藤江 亮之介, 藤原 翔, 黒蕨 馨, 大東 いずみ, 早坂 晴子 : Ccl21a 欠損マウスでの抗腫瘍免疫応答亢進における制御性 T 細胞の関与, 第45回日本分子生物学会年会, 2022年11月. | ... | |||||
B Lucas, AJ White, F Klein, C Veiga-Villauriz, A Handel, A Bacon, EJ Cosway, KD James, SM Parnell, Izumi Ohigashi, Yousuke Takahama, WE Jenkinson, GA Hollander, WY Lu and G Anderson : Embryonic keratin19+ progenitors generate multiple functionally distinct progeny to maintain epithelial diversity in the adult thymus medulla, Nature Communications, Vol.14, No.1, 2066, 2023. | ... | |||||
大東 いずみ, J. Andrea White, Mei-Ting Yang, 藤森 さゆ美, Grahama Anderson, 高浜 洋介 : ケモカインCCL21を発現する胸腺髄質上皮細胞は自己抗原発現髄質上皮細胞への分化活性を有する, 第32回 Kyoto T Cell Conference, 2023年6月. | ... | |||||
(種別) : Miyamoto Megumi, Kawato Yuki, Fujie Ryonosuke, Kurowarabe Kaoru, Fujiwara Kakeru, Nobusawa Reika, Hayashi Ryota, Ida Kei, Izumi Ohigashi and Hayasaka Haruko : CCL21-Ser expression in melanoma cells recruits CCR7+ naïve T cells to tumor tissues and promotes tumor growth, Cancer Science, Vol.114, No.9, 3509-3522, (発行所), (都市), Aug. 2023. | ... | |||||
Ryonosuke Fujie, Kaoru Kurowarabe, Yuki Yamada, Kakeru Fujiwara, Hayata Nakatani, Kenta Tsutsumi, Ryota Hayashi, Hinami Kawahata, Megumi Miyamoto, Madoka Ozawa, Tomoya Katakai, Yousuke Takahama, Izumi Ohigashi and Haruko Hayasaka : Endogenous CCL21-Ser deficiency reduces B16-F10 melanoma growth by enhanced antitumor immunity, Heliyon, Vol.9, No.8, e19215, 2023. | ... |
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