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著作: [細井 和雄]/Kobayashi, Shizuko/Ueha, Takao/Sex difference in L-glutamine D-fructose-6-phosphate aminotransferase activity of mouse submandibular gland/[Biochimica et Biophysica Acta (BBA) - General Subjects]

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EID
98068
EOID
711574
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LastModified
2013年9月11日(水) 21:40:34
Operator
大家 隆弘
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細井 和雄
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種別 必須 学術論文(審査論文)
言語 必須 英語
招待 推奨
審査 推奨 Peer Review
カテゴリ 推奨
共著種別 推奨
学究種別 推奨
組織 推奨
著者 必須
  1. 細井 和雄
    役割 任意
    貢献度 任意
    学籍番号 推奨
  2. (英) Kobayashi, Shizuko
    役割 任意
    貢献度 任意
    学籍番号 推奨
  3. (英) Ueha, Takao
    役割 任意
    貢献度 任意
    学籍番号 推奨
題名 必須

(英) Sex difference in L-glutamine D-fructose-6-phosphate aminotransferase activity of mouse submandibular gland

副題 任意
要約 任意

(英) L-Glutamine D-fructose-6-phosphate aminotransferase (2-amino-2-deoxy-D-glucose-6-phosphate ketol-isomerase (amino-transferring), EC 5.3.1.19) activities in the three main salivary glands of male and female mice were measured. It was found that the activity in the submandibular gland was about 10 times more in females than in males, whereas the activities in the sublingual and parotid glands of males and females were similar. The activity in the submandibular gland of female mice was not affected appreciably by ovariectomy but it decreased to the level in males on injection of testosterone. The activity in males was not affected appreciably by injection of progesterone or 17beta-estradiol, but it increased to the level in females after castration. The increased activity in castrated male mice was decreased again to the normal level by testosterone injection. Thus, this sex difference is caused by androgen, not by female hormones. On the basis of in vivo experiments using actinomycin D, it was suggested that testosterone produced an "enzyme inhibitor", which suppressed the enzyme activity in the submandibular glands of androgen-rich animals.

キーワード 推奨
  1. (英) Animals
  2. (英) Carbohydrate Epimerases
  3. (英) Castration
  4. (英) Dactinomycin
  5. (英) Female
  6. (英) Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)
  7. (英) Gonadal Steroid Hormones
  8. (英) Male
  9. (英) Mice
  10. (英) Sex
  11. (英) Subcellular Fractions
  12. (英) Submandibular Gland
  13. (英) Testosterone
発行所 推奨
誌名 必須 Biochimica et Biophysica Acta (BBA) - General Subjects([Elsevier Science])
(pISSN: 0304-4165)
ISSN 任意 0304-4165
ISSN: 0304-4165 (pISSN: 0304-4165, eISSN: 1872-8006)
Title: Biochimica et biophysica acta. General subjects
Title(ISO): Biochim Biophys Acta Gen Subj
Publisher: Elsevier BV
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
必須 543
必須 3
必須 283 292
都市 任意
年月日 必須 1978年 10月 18日
URL 任意
DOI 任意 10.1016/0304-4165(78)90046-6    (→Scopusで検索)
PMID 任意 708787    (→Scopusで検索)
NAID 任意
WOS 任意
Scopus 任意
評価値 任意
被引用数 任意
指導教員 推奨
備考 任意
  1. (英) Article.PublicationTypeList.PublicationType: Comparative Study

  2. (英) Article.PublicationTypeList.PublicationType: Journal Article