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著作: Kawanishi Ryosuke/Kakuta Nami/Sakai Yoko/Hari Yuki/Sasaki Hideto/Sekiguchi Ryo/[田中 克哉]/Desflurane improves lung collapse more than propofol during one-lung ventilation and reduces operation time in lobectomy by video-assisted thoracic surgery: a randomized controlled trial./[BMC Anesthesiology]

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EID
396612
EOID
1076380
Map
0
LastModified
2023年5月30日(火) 19:09:52
Operator
大家 隆弘
Avail
TRUE
Censor
0
Owner
田中 克哉
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種別 必須
言語 必須 英語
招待 推奨
審査 推奨
カテゴリ 推奨
共著種別 推奨
学究種別 推奨
組織 推奨
著者 必須
  1. (英) Kawanishi Ryosuke
    役割 任意
    貢献度 任意
    学籍番号 推奨
  2. (英) Kakuta Nami
    役割 任意
    貢献度 任意
    学籍番号 推奨
  3. (英) Sakai Yoko
    役割 任意
    貢献度 任意
    学籍番号 推奨
  4. (英) Hari Yuki
    役割 任意
    貢献度 任意
    学籍番号 推奨
  5. (英) Sasaki Hideto
    役割 任意
    貢献度 任意
    学籍番号 推奨
  6. (英) Sekiguchi Ryo
    役割 任意
    貢献度 任意
    学籍番号 推奨
  7. 田中 克哉([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.麻酔・疼痛治療医学]/[徳島大学.病院.診療科.脳·神経·精神科])
    役割 任意
    貢献度 任意
    学籍番号 推奨
題名 必須

(英) Desflurane improves lung collapse more than propofol during one-lung ventilation and reduces operation time in lobectomy by video-assisted thoracic surgery: a randomized controlled trial.

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(英) This study evaluated whether desflurane improved lung collapse during one-lung ventilation (OLV) more than propofol, and whether it could reduce the operation time of video-assisted thoracic surgery. Sixty patients undergoing lobectomy by video-assisted thoracic surgery (VATS) were randomly assigned to general anesthesia with desflurane or propofol. Lungs were inspected by thoracoscope at 10, 30, and 60 min after initiation of OLV. After surgery, the Lung Collapse Score, a composite of lung color and volume assessments, was assigned by two clinicians blinded to the anesthetic regimen. The primary outcome was operation time. The secondary outcome included the complication rate. Of the 60 participants, 50 completed the study, 26 in Desflurane group and 24 in Propofol group. The Lung Collapse Scores at 30 and 60 min after OLV initiation were significantly better in Desflurane group than in Propofol group, and operation time was significantly shorter in Desflurane group (214 (57) min vs. 262 (72) min [mean (SD)], difference in means, -48; 95% CI, -85 to -11; P = 0.01). The incidence of multiple complications was 1/26 (3%) and 6/24 (25%) in Desflurane and Propofol group, respectively (relative risk, 0.1; 95% CI, 0.02 to 1.18; P = 0.04). Desflurane improved lung collapse during OLV and significantly shortened VATS lobectomy operation time compared to propofol in our studied patients. Desflurane resulted in fewer postoperative complications. Thus, desflurane may be an appropriate anesthetic during lobectomy by VATS requiring OLV. The study was registered with the University Hospital Medical Information Network ( UMIN000009412 ). The date of disclosure of this study information is 27/11/2012. On this date, we registered the study into UMIN; patients were included from 2013 to 2014. However, on 11/27/2015, the UMIN system administrator suggested a detailed description. Thereafter, we added it to the Randomization Unit. Despite being prospective, it was retrospectively registered on UMIN for the above reasons.

キーワード 推奨
  1. (英) Anesthetics
  2. (英) Desflurane
  3. (英) Humans
  4. (英) Isoflurane
  5. (英) Lung
  6. (英) One-Lung Ventilation
  7. (英) Propofol
  8. (英) Prospective Studies
  9. (英) Pulmonary Atelectasis
  10. (英) Thoracic Surgery, Video-Assisted
発行所 推奨
誌名 必須 BMC Anesthesiology([BioMed Central Ltd.])
(eISSN: 1471-2253)
ISSN 任意 1471-2253
ISSN: 1471-2253 (eISSN: 1471-2253)
Title: BMC anesthesiology
Title(ISO): BMC Anesthesiol
Publisher: BioMed Central
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
必須 22
必須 1
必須 125 125
都市 任意
年月日 必須 2022年 4月 29日
URL 任意
DOI 任意 10.1186/s12871-022-01669-7    (→Scopusで検索)
PMID 任意 35488195    (→Scopusで検索)
CRID 任意
WOS 任意
Scopus 任意
評価値 任意
被引用数 任意
指導教員 推奨
備考 任意
  1. (英) Article.ELocationID: 125

  2. (英) Article.ELocationID: 10.1186/s12871-022-01669-7

  3. (英) Article.DataBankList.DataBank.DataBankName: UMIN-CTR

  4. (英) Article.DataBankList.DataBank.AccessionNumberList.AccessionNumber: UMIN000009412

  5. (英) Article.PublicationTypeList.PublicationType: Journal Article

  6. (英) Article.PublicationTypeList.PublicationType: Randomized Controlled Trial

  7. (英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't

  8. (英) KeywordList.Keyword: Desflurane

  9. (英) KeywordList.Keyword: Lung collapse

  10. (英) KeywordList.Keyword: One-lung ventilation

  11. (英) KeywordList.Keyword: Propofol

  12. (英) CoiStatement: The authors declare that they have no competing interests.