徳島大学 教育・研究者情報データベース(EDB)

1. 佐藤 康史([徳島大学.病院.診療科.内科.消化器内科])

   役割	任意
   貢献度	任意
   学籍番号	推奨

2. 岡本 耕一([徳島大学.病院.診療科.内科.消化器内科])

   役割	任意
   貢献度	任意
   学籍番号	推奨

3. 宮本 弘志([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.消化器内科学]/[徳島大学.病院.診療科.内科.消化器内科])

   役割	任意
   貢献度	任意
   学籍番号	推奨

4. 高山 哲治([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.消化器内科学])

   役割	任意
   貢献度	任意
   学籍番号	推奨

(英) Chemotherapy in older adults with gastrointestinal cancer:Current practices and future directions in Japan.

(英) Chemotherapy for cancer has significantly improved owing to the increasing number of effective chemotherapeutic agents and supportive care. Recently, the number of older cancer patients has rapidly increased owing to the aging of the global population. However, in most cases, it is difficult to treat those using similar dosages or schedules as that of younger patients because older patients generally have unfavorable factors, such as decreased performance status and physical and cognitive conditions, thus increasing the incidence of complications and side effects. Chemotherapy for gastrointestinal cancers has made significant progress in recent years with the introduction of molecular-targeted agents and immunotherapy. However, clinical trials showed limited evidence regarding the efficacy of chemotherapy in older cancer patients, accounting for half of all patients, making it difficult to develop a well-established treatment strategy. This review aimed to evaluate the current state of chemotherapy for gastrointestinal cancer in older adults. Furthermore, the limitations and future perspectives were discussed. J. Med. Invest. 69 : 25-30, February, 2022.

1. (英) Aged
2. (英) Antineoplastic Agents
3. (英) Antineoplastic Combined Chemotherapy Protocols
4. (英) Gastrointestinal Neoplasms
5. (英) Humans
6. (英) Japan

1. (英) PublicationType: Journal Article

2. (英) PublicationType: Review