著作: Tomasz D Pieczonka/Aneta M Bragiel-Pieczonka/[竹内 祐子]/[柳沢 志津子]/[吉岡 昌美]/[石川 康子]/Effect of oral administration of Jersey cow defatted milk on salivary volume and composition in elderly persons/[The Journal of Medical Investigation : JMI]
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削除する| 種別 | 必須 | 学術論文(審査論文) | |||
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| 言語 | 必須 | 英語 | |||
| 招待 | 推奨 | ||||
| 審査 | 推奨 | ||||
| カテゴリ | 推奨 | ||||
| 共著種別 | 推奨 | ||||
| 学究種別 | 推奨 | ||||
| 組織 | 推奨 | ||||
| 著者 | 必須 | ||||
| 題名 | 必須 |
(英) Effect of oral administration of Jersey cow defatted milk on salivary volume and composition in elderly persons |
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| 副題 | 任意 | ||||
| 要約 | 任意 |
(英) The administration of Leu57-Leu58-His59-Lys60 (LLHK), Leu58-His59-Lys60 (LHK), and His59-Lys60 (HK) from β-lactoglobulin C variant, which is specific to Jersey cow milk, has been shown to prevent and/or restore the age-dependent atrophy and functional decline of salivary glands by affecting gene expression in elderly rats. In this study, we investigated the effect of Jersey cow defatted milk on salivary volume and composition in elderly persons. Participants (aged 85 to 98, n = 8) were administered defatted dry milk from Jersey cows twice a day for 4 weeks. Before and after 4 weeks from the start of drinking, saliva was collected and weighed. Salivary cystatin S and amylase levels were analyzed by Western blotting. To assess the effect of Jersey cow defatted milk on taste perception, questionnaires were used. Salivary volume after oral administration of 40 g of Jersey cow defatted dry milk daily for 4 weeks was 1.8 times higher than that before administration. Salivary cystatin S and amylase levels significantly increased after administration of Jersey cow defatted dry milk. Moreover, all participants who had taste impairment reported improved taste perception after administration. The administration of Jersey cow defatted dry milk increased salivary volume and changed the composition of saliva in elderly persons. Furthermore, it improved taste perception. J. Med. Invest. 68 : 280-285, August, 2021. |
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| キーワード | 推奨 |
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| 発行所 | 推奨 | ||||
| 誌名 | 必須 |
The Journal of Medical Investigation : JMI([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)
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| 巻 | 必須 | 68 | |||
| 号 | 必須 | 3.4 | |||
| 頁 | 必須 | 280 285 | |||
| 都市 | 任意 | ||||
| 年月日 | 必須 | 2021年 7月 初日 | |||
| URL | 任意 | ||||
| DOI | 任意 | 10.2152/jmi.68.280 (→Scopusで検索) | |||
| PMID | 任意 | 34759145 (→Scopusで検索) | |||
| CRID | 任意 | 1390852967475385344 | |||
| NAID | 130008115643 | ||||
| WOS | 任意 | ||||
| Scopus | 任意 | ||||
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| 指導教員 | 推奨 | ||||
| 備考 | 任意 |
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