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著作: Yamanaka Moriaki/Shinya Takayoshi/[音見 暢一]/Kubo Michiko/Arai Yuta/Toba Hiroaki/Bando Yoshimi/Otsuka Hideki/Harada Masafumi/Semiquantitative assessment of fluorodeoxyglucose uptake in primary tumours on dynamic PET/computed tomography for lymph node metastasis evaluation in patients with lung cancer: a prospective study./[Nuclear Medicine Communications]

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EID
379535
EOID
1022471
Map
0
LastModified
2021年10月26日(火) 14:04:19
Operator
三木 ちひろ
Avail
TRUE
Censor
0
Owner
音見 暢一
Read
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種別 必須
言語 必須 英語
招待 推奨
審査 推奨
カテゴリ 推奨
共著種別 推奨
学究種別 推奨
組織 推奨
著者 必須
  1. (英) Yamanaka Moriaki
    役割 任意
    貢献度 任意
    学籍番号 推奨
  2. (英) Shinya Takayoshi
    役割 任意
    貢献度 任意
    学籍番号 推奨
  3. 音見 暢一([徳島大学.病院.中央診療施設等.放射線部]/[徳島大学.病院.診療科.放射線科.放射線診断科])
    役割 任意
    貢献度 任意
    学籍番号 推奨
  4. (英) Kubo Michiko
    役割 任意
    貢献度 任意
    学籍番号 推奨
  5. (英) Arai Yuta
    役割 任意
    貢献度 任意
    学籍番号 推奨
  6. (英) Toba Hiroaki
    役割 任意
    貢献度 任意
    学籍番号 推奨
  7. (英) Bando Yoshimi
    役割 任意
    貢献度 任意
    学籍番号 推奨
  8. (英) Otsuka Hideki
    役割 任意
    貢献度 任意
    学籍番号 推奨
  9. (英) Harada Masafumi
    役割 任意
    貢献度 任意
    学籍番号 推奨
題名 必須

(英) Semiquantitative assessment of fluorodeoxyglucose uptake in primary tumours on dynamic PET/computed tomography for lymph node metastasis evaluation in patients with lung cancer: a prospective study.

副題 任意
要約 任意

(英) To semiquantitatively estimate fluorine-18-fluorodeoxyglucose (FDG) uptake in primary lung cancer cells using dynamic and dual-time-point (DTP) PET/computed tomography (PET/CT) to obtain a diagnostic index for lymph node metastasis. Forty-five patients with lung cancer underwent dynamic and DTP PET/CT examinations. All primary lesions and lymph node metastases were evaluated pathologically. At each time phase, we assessed the maximum standardised uptake value (SUVmax), metabolic tumour volume (MTV) and total lesion glycolysis (TLG) of the primary tumours. We investigated the relationship between semiquantitative index and the presence of lymph node metastasis for each case and for all cases satisfying indications for segmentectomy. In cases with lymph node metastasis, we assessed the SUVmax of pathologically proven metastatic lymph nodes and nonmetastatic lymph nodes in each dynamic phase for evaluating temporal change. Among 45 patients, 15 had 17 lymph node metastasis. SUVmax, MTV and TLG of primary tumours at each time phase were significantly associated with lymph node metastasis (P < 0.05). In receiver operating characteristic analysis, dynamic second and third phases showed high diagnostic ability for lymph node metastasis. The temporal change in SUVmax in the dynamic phase between primary tumours and metastatic lymph nodes were significantly different (P = 0.065). The temporal change in SUVmax was significantly lower in nonmetastatic lymph nodes than in primary tumours and metastatic lymph nodes (P < 0.0001). Semiquantitative assessment of FDG uptake in dynamic second and third phases and the assessment of temporal changes in SUVmax on dynamic PET/CT scans were important predictors in diagnosing lymph node metastasis.

キーワード 推奨
  1. (英) Adult
  2. (英) Aged
  3. (英) Aged, 80 and over
  4. (英) Biological Transport
  5. 女性(female)
  6. (英) Fluorodeoxyglucose F18
  7. (英) Glycolysis
  8. (英) Humans
  9. (英) Lung Neoplasms
  10. (英) Lymphatic Metastasis
  11. 男性(male)
  12. (英) Middle Aged
  13. (英) Positron Emission Tomography Computed Tomography
  14. (英) Prospective Studies
  15. (英) Tumor Burden
発行所 推奨
誌名 必須 Nuclear Medicine Communications(British Nuclear Medicine Society)
(pISSN: 0143-3636, eISSN: 1473-5628)
ISSN 任意 1473-5628
ISSN: 0143-3636 (pISSN: 0143-3636, eISSN: 1473-5628)
Title: Nuclear medicine communications
Title(ISO): Nucl Med Commun
Publisher: Lippincott Williams & Wilkins Ltd.
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
必須 41
必須 11
必須 1189 1198
都市 任意
年月日 必須 2020年 11月 初日
URL 任意
DOI 任意 10.1097/MNM.0000000000001271    (→Scopusで検索)
PMID 任意 32796454    (→Scopusで検索)
NAID 任意
WOS 任意
Scopus 任意
評価値 任意
被引用数 任意
指導教員 推奨
備考 任意
  1. (英) Article.ELocationID: 10.1097/MNM.0000000000001271

  2. (英) Article.PublicationTypeList.PublicationType: Clinical Trial

  3. (英) Article.PublicationTypeList.PublicationType: Journal Article