徳島大学 教育・研究者情報データベース(EDB)

1. 山田 直輝([徳島大学.病院.先端医療開発研究プロジェクト]/[徳島大学.病院.診療科.脳·神経·精神科.精神科神経科])

   役割	任意
   貢献度	任意
   学籍番号	推奨

2. 中土井 芳弘

   役割	任意
   貢献度	任意
   学籍番号	推奨

3. (英) Fukuma Ryosuke

   役割	任意
   貢献度	任意
   学籍番号	推奨

4. 大森 哲郎

   役割	任意
   貢献度	任意
   学籍番号	推奨

(英) Two children exhibiting social withdrawal, school refusal, and underlying generalized anxiety disorder successfully treated using a selective serotonin reuptake inhibitor.

(英) Generalized anxiety disorder (GAD) sometimes exists in the background of social withdrawal and school refusal. Although clinical evidence suggests that selective serotonin reuptake inhibitors (SSRIs) are an effective treatment for GAD, they are not officially approved for GAD in Japan. In addition, it has been established that the use of SSRIs increases the risk for suicide and activation syndrome among young individuals. As such, there is currently little domestic clinical experience in prescribing SSRIs to young patients with GAD. The authors report two cases involving 10-year-old patients with GAD who were treated successfully with escitalopram and experienced subsequent improvement in social withdrawal and school refusal. One patient had autistic spectrum disorder and exhibited self-harm associated with anxiety symptoms, requiring careful use of SSRIs under hospitalization. The other patient was treated at an outpatient clinic without any side effects. In each case, improvement of anxiety symptoms with the use of SSRIs facilitated the introduction of psychoeducation and psychotherapy. It is important to accurately diagnose GAD, which may exist in the background of patients exhibiting social withdrawal and school refusal, and to treat the disorder appropriately. J. Med. Invest. 67 : 355-357, August, 2020.

1. (英) PublicationType: Journal Article