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著作: [中川 貴之]/[工藤 景子]/[福田 直志]/Tachikawa Noriko/Koyano Kiyoshi/Matsushita Yasuyuki/石川 邦夫/[宮本 洋二]/Application of low-crystalline carbonate apatite granules in 2-stage sinus floor augmentation: a prospective clinical trial and histomorphometric evaluation./[Journal of Periodontal & Implant Science]

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EID
368686
EOID
990641
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2020年9月1日(火) 20:25:00
Operator
大家 隆弘
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宮本 洋二
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種別 必須 学術論文(審査論文)
言語 必須 英語
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著者 必須
  1. 中川 貴之
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  2. 工藤 景子([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.臨床歯学系.口腔外科学])
    役割 任意
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  3. 福田 直志([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.臨床歯学系.口腔外科学])
    役割 任意
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    学籍番号 推奨
  4. (英) Tachikawa Noriko
    役割 任意
    貢献度 任意
    学籍番号 推奨
  5. (英) Koyano Kiyoshi
    役割 任意
    貢献度 任意
    学籍番号 推奨
  6. (英) Matsushita Yasuyuki
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  7. (英) Ishikawa Kunio / (日) 石川 邦夫
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    学籍番号 推奨
  8. 宮本 洋二([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.臨床歯学系.口腔外科学])
    役割 任意
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    学籍番号 推奨
題名 必須

(英) Application of low-crystalline carbonate apatite granules in 2-stage sinus floor augmentation: a prospective clinical trial and histomorphometric evaluation.

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(英) The purpose of this study was to elucidate the efficacy and safety of carbonate apatite (COAp) granules in 2-stage sinus floor augmentation through the radiographic and histomorphometric assessment of bone biopsy specimens. Two-stage sinus floor augmentation was performed on 13 patients with a total of 17 implants. Radiographic assessment using panoramic radiographs was performed immediately after augmentation and was also performed 2 additional times, at 7±2 months and 18±2 months post-augmentation, respectively. Bone biopsy specimens taken from planned implant placement sites underwent micro-computed tomography, after which histological sections were prepared. Postoperative healing of the sinus floor augmentation was uneventful in all cases. The mean preoperative residual bone height was 3.5±1.3 mm, and this was increased to 13.3±1.7 mm by augmentation with the COAp granules. The mean height of the augmented site had decreased to 10.7±1.9 mm by 7±2 months after augmentation; however, implants with lengths in the range of 6.5 to 11.5 mm could still be placed. The mean height of the augmented site had decreased to 9.6±1.4 mm by 18±2 months post-augmentation. No implant failure or complications were observed. Few inflammatory cells or foreign body giant cells were observed in the bone biopsy specimens. Although there were individual differences in the amount of new bone detected, new bone was observed to be in direct contact with the COAp granules in all cases, without an intermediate layer of fibrous tissue. The amounts of bone and residual COAp were 33.8%±15.1% and 15.3%±11.9%, respectively. In this first demonstration, low-crystalline COAp granules showed excellent biocompatibility, and bone biopsy showed them to be replaced with bone in humans. COAp granules are a useful and safe bone substitute for two-stage sinus floor augmentation. ICTRP Identifier: JPRN-UMIN000019281.

キーワード 推奨
発行所 推奨
誌名 必須 Journal of Periodontal & Implant Science(Korean Academy of Periodontology)
(pISSN: 2093-2278, eISSN: 2093-2286)
ISSN 任意 2093-2278
ISSN: 2093-2278 (pISSN: 2093-2278, eISSN: 2093-2286)
Title: Journal of periodontal & implant science
Title(ISO): J Periodontal Implant Sci
Publisher: Korean Academy of Periodontology
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
必須 49
必須 6
必須 382 396
都市 任意
年月日 必須 2019年 12月 初日
URL 任意
DOI 任意 10.5051/jpis.2019.49.6.382    (→Scopusで検索)
PMID 任意 31886030    (→Scopusで検索)
NAID 任意
WOS 任意
Scopus 任意
評価値 任意
被引用数 任意
指導教員 推奨
備考 任意
  1. (英) Article.ELocationID: 10.5051/jpis.2019.49.6.382

  2. (英) Article.PublicationTypeList.PublicationType: Journal Article

  3. (英) KeywordList.Keyword: Apatites

  4. (英) KeywordList.Keyword: Dental implant

  5. (英) KeywordList.Keyword: Sinus floor augmentation

  6. (英) CoiStatement: Conflict of Interest: No potential conflict of interest relevant to this article was reported.