365846: [岡久稔也]/[曽我部正弘]/[中川忠彦]/[田中久美子]/[友成哲]/[谷口達哉]/[髙橋章]/[木内陽介]/西岡潤司/井形直紀/[楊河宏章]/Komatsu takatoshi/Ohnishi Yoshiaki/Fukuhara Masashi/Ishikawa Masashi/[柴田啓志]/Shinomiya Hirohiko/Nakasono Masahiko/Kishi Fumiko/Komai Keiko/Tatsuki Yayoi/Murashima Toru/Deguchi Yoshihiro/Aramaki Hiroshi/Fukumitsu Hideyuki/[高山哲治]/Development of a novel automatic ascites filtration and concentration equipment with multi-ring-type roller pump units for cell-free and concentrated ascites reinfusion therapy./[Artificial Organs]

著作: [岡久稔也]/[曽我部正弘]/[中川忠彦]/[田中久美子]/[友成哲]/[谷口達哉]/[髙橋章]/[木内陽介]/西岡潤司/井形直紀/[楊河宏章]/Komatsu takatoshi/Ohnishi Yoshiaki/Fukuhara Masashi/Ishikawa Masashi/[柴田啓志]/Shinomiya Hirohiko/Nakasono Masahiko/Kishi Fumiko/Komai Keiko/Tatsuki Yayoi/Murashima Toru/Deguchi Yoshihiro/Aramaki Hiroshi/Fukumitsu Hideyuki/[高山哲治]/Development of a novel automatic ascites filtration and concentration equipment with multi-ring-type roller pump units for cell-free and concentrated ascites reinfusion therapy./[Artificial Organs]

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EID: 365846
EOID: 983619
Map: 0
LastModified: 2020年7月31日(金) 14:16:38
Operator: 大家隆弘
Avail: TRUE
Censor: 0
Owner: 高山哲治
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種別

必須

学術論文(審査論文)

言語

必須

英語

招待

推奨

審査

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カテゴリ

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共著種別

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学究種別

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組織

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著者

必須

岡久稔也([徳島大学.大学院医歯薬学研究部.医学域.連携研究部門(医学域).寄附講座系(医学域).地域総合医療学]/[徳島大学.病院.診療科.内科.消化器内科])

役割任意

貢献度任意

学籍番号推奨
曽我部正弘([徳島大学.キャンパスライフ健康支援センター])

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貢献度任意

学籍番号推奨
中川忠彦

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貢献度任意

学籍番号推奨
田中久美子

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学籍番号推奨 ****
友成哲

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貢献度任意

学籍番号推奨 ****
谷口達哉

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学籍番号推奨
髙橋章([徳島大学.大学院医歯薬学研究部.医学域.栄養科学部門.医科栄養学系.予防環境栄養学])

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木内陽介

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(英) Nishioka Junji / (日) 西岡潤司 / (読) にしおかじゅんじ

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(英) Igata Naoki / (日) 井形直紀 / (読) いがたなおき

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楊河宏章

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(英) Komatsu takatoshi

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(英) Ohnishi Yoshiaki

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(英) Fukuhara Masashi

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(英) Ishikawa Masashi

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柴田啓志

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(英) Shinomiya Hirohiko

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(英) Nakasono Masahiko

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(英) Kishi Fumiko

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(英) Komai Keiko

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(英) Tatsuki Yayoi

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(英) Murashima Toru

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(英) Deguchi Yoshihiro

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貢献度任意

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(英) Aramaki Hiroshi

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(英) Fukumitsu Hideyuki

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学籍番号推奨
高山哲治([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.消化器内科学])

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題名

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(英) Development of a novel automatic ascites filtration and concentration equipment with multi-ring-type roller pump units for cell-free and concentrated ascites reinfusion therapy.

副題

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要約

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(英) Cell-free and concentrated ascites reinfusion therapy (CART) is an effective therapy for refractory ascites. However, CART is difficult to perform as ascites filtration and concentration is a complicated procedure. Moreover, the procedure requires the constant assistance of a clinical engineer or/and the use of an expensive equipment for the multi-purpose blood processing. Therefore, we developed a CART specialized equipment (mobility CART [M-CART]) that could be used safely with various safety measures and automatic functions such as automatic washing of clogged filtration filter and self-regulation of the concentration ratio. Downsizing, lightning of the weight, and automatic processing in M-CART required the use of newly developed multi-ring-type roller pump units. This equipment was approved under Japanese regulations in 2018. In performing 41 sessions of CART (for malignant ascites, 22 sessions; and hepatic ascites, 19 sessions) using this equipment in 17 patients, no serious adverse event occurred. An average of 4494 g of ascites was collected and the total amount of ascites was processed in all the sessions without any trouble. The mean weight of the processed ascites was 560 g and the mean concentration ratio was 8.0. The ascites were processed at a flow rate of 50 mL/min. The mean ascites processing time was 112.5 minutes and a 106.5-minutes (95.2%) ascites processing was performed automatically. The operator responded to alarms or support information 3.2 times on average (3.1 minutes, 2.1% of ascites processing time). Human errors related to ascites processing were detected by M-CART at 0.4 times per session on average and were appropriately addressed by the operator. The frequencies of automatic washing of clogged filtration filter and self-regulation of the concentration ratio were 31.7% and 53.7%, respectively. The mean recovery rates (recovery dose) of protein, albumin, and immunoglobulin G were 72.9%, 72.9%, and 71.2% (65.9 g, 34.9 g, and 13.2 g), respectively. Steroids were administered in 92.7% of the sessions to prevent fever and the mean increase in body temperature was 0.53°C. M-CART is a compact and lightweight automatic CART specialized equipment that can safely and easily process a large quantity of ascites without the constant assistance of an operator.

キーワード

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発行所

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誌名

必須

Artificial Organs(International Federation for Artificial Organs)

(pISSN: 0160-564X, eISSN: 1525-1594)

ISSN	任意	1525-1594 ISSN: 0160-564X (pISSN: 0160-564X, eISSN: 1525-1594) Title: Artificial organs Title(ISO): Artif Organs Supplier: International Federation for Artificial Organs (IFAO) Publisher: Blackwell (NLM Catalog) (Wiley) (Scopus) (CrossRef) (Scopus information is found. [need login])

巻

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号

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頁

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856 872

都市

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年月日

必須

2020年 5月 18日

URL

任意

DOI

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10.1111/aor.13681 (→Scopusで検索)

PMID

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32187379 (→Scopusで検索)

CRID

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Scopus

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備考

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(英) Article.ELocationID: 10.1111/aor.13681
(英) Article.PublicationTypeList.PublicationType: Journal Article
(英) KeywordList.Keyword: automatic ascites processing
(英) KeywordList.Keyword: cell-free and concentrated ascites reinfusion therapy
(英) KeywordList.Keyword: refractory ascites

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