著作: Fukushima Shu-ichiro/Yonetsu Makoto/[安井 武史]/Polarization-resolved second-harmonic-generation imaging of dermal collagen fiber in prewrinkled and wrinkled skins of ultraviolet-B-exposed mouse/[Journal of Biomedical Optics]
ヘルプを読む
「著作」（著作（著書，論文，レター，国際会議など））は，研究業績にかかる著作（著書，論文，レター，国際会議など）を登録するテーブルです． (この情報が属するテーブルの詳細な定義を見る)
- 項目名の部分にマウスカーソルを置いて少し待つと，項目の簡単な説明がツールチップ表示されます．
編集する
複製して登録
削除する| 種別 | 必須 | 学術論文(審査論文) | |||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 言語 | 必須 | 英語 | |||||||||||||||||||||||||||
| 招待 | 推奨 | ||||||||||||||||||||||||||||
| 審査 | 推奨 | Peer Review | |||||||||||||||||||||||||||
| カテゴリ | 推奨 | 研究 | |||||||||||||||||||||||||||
| 共著種別 | 推奨 | 国内共著(徳島大学内研究者と国内(学外)研究者との共同研究 (国外研究者を含まない)) | |||||||||||||||||||||||||||
| 学究種別 | 推奨 | ||||||||||||||||||||||||||||
| 組織 | 推奨 | ||||||||||||||||||||||||||||
| 著者 | 必須 |
|
|||||||||||||||||||||||||||
| 題名 | 必須 |
(英) Polarization-resolved second-harmonic-generation imaging of dermal collagen fiber in prewrinkled and wrinkled skins of ultraviolet-B-exposed mouse |
|||||||||||||||||||||||||||
| 副題 | 任意 | ||||||||||||||||||||||||||||
| 要約 | 任意 |
(英) Skin wrinkling is a typical symptom of cutaneous photoaging; however, the skin wrinkling depends on not only the actual age but also exposure history to ultraviolet B (UVB) rays in individuals. Therefore, there is considerable need for its assessment technique in vivo in skin cosmetics and antiaging dermatology. Wrinkles always appear as linear grooves in the skin, and dermal collagen fibers play an important role to determine the morphology and mechanical properties of the skin. Therefore, an optical probe sensitive to dermal collagen fiber and its orientation will be useful. Polarization-resolved second-harmonic-generation (SHG) microscopy is a promising approach for in vivo evaluation of collagen fiber orientation because the efficiency of SHG light is sensitive to collagen fiber orientation when the incident light is linearly polarized. We investigate orientation change of dermal collagen fiber in prewrinkled and wrinkled skins of the UVB-exposed mouse model using polarization-resolved SHG microscopy. A polarization anisotropic image of the SHG light indicates that the change of collagen fiber orientation starts in the prewrinkled skin of UVB-exposed mice, then the wrinkle appears. Furthermore, the dominant direction of collagen fiber orientation in the prewrinkled skin is significantly parallel to the wrinkle direction in the wrinkled skin. This result implies that the change of collagen fiber orientation is a trigger of wrinkling in cutaneous photoaging. |
|||||||||||||||||||||||||||
| キーワード | 推奨 | ||||||||||||||||||||||||||||
| 発行所 | 推奨 | SPIE The International Society for Optical Engineering | |||||||||||||||||||||||||||
| 誌名 | 必須 |
Journal of Biomedical Optics(Society of Photo-optical Instrumentation Engineers/International Biomedical Optics Society)
(pISSN: 1083-3668, eISSN: 1560-2281)
|
|||||||||||||||||||||||||||
| 巻 | 必須 | 24 | |||||||||||||||||||||||||||
| 号 | 必須 | 3 | |||||||||||||||||||||||||||
| 頁 | 必須 | 031006 031006 | |||||||||||||||||||||||||||
| 都市 | 任意 | ||||||||||||||||||||||||||||
| 年月日 | 必須 | 2018年 8月 17日 | |||||||||||||||||||||||||||
| URL | 任意 | ||||||||||||||||||||||||||||
| DOI | 任意 | 10.1117/1.JBO.24.3.031006 (→Scopusで検索) | |||||||||||||||||||||||||||
| PMID | 任意 | 30191685 (→Scopusで検索) | |||||||||||||||||||||||||||
| CRID | 任意 | ||||||||||||||||||||||||||||
| WOS | 任意 | ||||||||||||||||||||||||||||
| Scopus | 任意 | ||||||||||||||||||||||||||||
| 評価値 | 任意 | ||||||||||||||||||||||||||||
| 被引用数 | 任意 | ||||||||||||||||||||||||||||
| 指導教員 | 推奨 | ||||||||||||||||||||||||||||
| 備考 | 任意 |
|
|||||||||||||||||||||||||||