徳島大学 教育・研究者情報データベース(EDB)

1. 江川 麻理子([徳島大学.病院.診療科.感覚·皮膚·運動機能科.眼科])

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2. 三田村 佳典([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.眼科学])

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3. 仁木 昌徳

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4. (英) Sano Hiroki / (日) 佐埜 弘樹 / (読) さの ひろき

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5. (英) Miura Gen

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6. (英) Chiba Akihiro

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7. (英) Yamamoto Shuichi

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8. (英) Sonoda Shozo

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9. (英) Sakamoto Taiji

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(英) CORRELATIONS BETWEEN CHOROIDAL STRUCTURES AND VISUAL FUNCTIONS IN EYES WITH RETINITIS PIGMENTOSA

(英) To investigate the choroidal structures in the enhanced depth imaging optical coherence tomographic images in eyes with retinitis pigmentosa (RP) and to determine correlations between the choroidal structures and visual functions. The enhanced depth imaging optical coherence tomographic images of 100 eyes with typical RP and 60 age-, sex-, and axial length-matched normal eyes were binarized using ImageJ. The cross-sectional luminal and stromal areas of the inner and outer subfoveal choroid of 1,500-µm width were measured. The inner choroid included the choriocapillaris and medium vessel layer, and the outer choroid included the larger vessel layer. In the inner choroid, the luminal area and the ratio of luminal/total choroidal area (L/C ratio) were significantly smaller in RP than in controls (P = 0.010, P < 0.001, respectively), whereas the stromal area was not significantly different (P = 0.114). The inner choroidal L/C ratio was significantly correlated with the best-corrected visual acuity, mean deviation, foveal sensitivity, width of the ellipsoid zone, and central foveal thickness in RP after adjusting for the axial length, age, and sex (all P < 0.005). The significant correlations between the inner choroidal structures and the visual functions and retinal structures indicate that the choroidal structures are altered in association with the progression of RP.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

1. (英) Article.ELocationID: 10.1097/IAE.0000000000002285

2. (英) Article.PublicationTypeList.PublicationType: Journal Article