著作: [早渕 康信]/Homma Yukako/[香美 祥二]/Optical coherence tomography for observing development of pulmonary arterial vasa vasorum after bidirectional cavopulmonary connection in children./[PLoS ONE]
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種別 | 必須 | 学術論文(審査論文) | |||
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言語 | 必須 | 英語 | |||
招待 | 推奨 | ||||
審査 | 推奨 | Peer Review | |||
カテゴリ | 推奨 | 研究 | |||
共著種別 | 推奨 | ||||
学究種別 | 推奨 | ||||
組織 | 推奨 | ||||
著者 | 必須 | ||||
題名 | 必須 |
(英) Optical coherence tomography for observing development of pulmonary arterial vasa vasorum after bidirectional cavopulmonary connection in children. |
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副題 | 任意 | ||||
要約 | 任意 |
(英) Hypoxia and low pulmonary arterial (PA) blood flow stimulate the development of systemic-to-pulmonary collateral blood vessels, which can be an adverse factor when performing the Fontan operation. The aim of this study was to use optical coherence tomography (OCT) to elucidate the morphological changes in PA vasculature after creation of a bidirectional cavopulmonary connection (BCPC) in children. This prospective study evaluated PA wall thickness and development of PA vasa vasorum (VV) in the distal PA of eight patients (BCPC group, 1.3 0.3 years) and 20 age-matched children with normal pulmonary artery hemodynamics and morphology (Control group, 1.4 0.3 years). VV development was defined by the VV area ratio, defined as the VV area divided by the adventitial area in cross-sectional images. There was no significant difference in PA wall thickness between the BCPC and control groups (0.12 0.03 mm vs. 0.12 0.02 mm, respectively). The VV area ratio was significantly greater in the BCPC group than in the Control group (14.5 3.5% vs. 5.3 1.6%, respectively; p<0.0001). OCT is a promising new tool for evaluating PA pathology, including the development of VV in patients after BCPC. |
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キーワード | 推奨 | ||||
発行所 | 推奨 | ||||
誌名 | 必須 |
PLoS ONE(Public Library of Science)
(eISSN: 1932-6203)
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巻 | 必須 | 14 | |||
号 | 必須 | 4 | |||
頁 | 必須 | e0215146 e0215146 | |||
都市 | 任意 | ||||
年月日 | 必須 | 2019年 4月 8日 | |||
URL | 任意 | ||||
DOI | 任意 | 10.1371/journal.pone.0215146 (→Scopusで検索) | |||
PMID | 任意 | 30958848 (→Scopusで検索) | |||
CRID | 任意 | ||||
WOS | 任意 | ||||
Scopus | 任意 | ||||
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指導教員 | 推奨 | ||||
備考 | 任意 |
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