著作: [中村 教泰]/Hayashi Koichiro/Kubo Hitoshi/[原田 雅史]/Izumi Keisuke/[鶴尾 吉宏]/Yogo Toshinobu/Mesoscopic multimodal imaging provides new insight to tumor tissue evaluation: an example of macrophage imaging of hepatic tumor using organosilica nanoparticles./[Scientific Reports]
ヘルプを読む
「著作」(著作(著書,論文,レター,国際会議など))は,研究業績にかかる著作(著書,論文,レター,国際会議など)を登録するテーブルです. (この情報が属するテーブルの詳細な定義を見る)
- 項目名の部分にマウスカーソルを置いて少し待つと,項目の簡単な説明がツールチップ表示されます.
種別 | 必須 | 学術論文(審査論文) | |||
---|---|---|---|---|---|
言語 | 必須 | 英語 | |||
招待 | 推奨 | ||||
審査 | 推奨 | ||||
カテゴリ | 推奨 | ||||
共著種別 | 推奨 | ||||
学究種別 | 推奨 | ||||
組織 | 推奨 | ||||
著者 | 必須 | ||||
題名 | 必須 |
(英) Mesoscopic multimodal imaging provides new insight to tumor tissue evaluation: an example of macrophage imaging of hepatic tumor using organosilica nanoparticles. |
|||
副題 | 任意 | ||||
要約 | 任意 |
(英) Multimodal imaging using novel multifunctional nanoparticles provides new approach to biomedical field. Thiol-organosilica nanoparticles containing iron oxide magnetic nanoparticles (MNPs) and rhodamine B (thiol OS-MNP/Rho) were applied to multimodal imaging of hepatic tumor of Long-Evans Cinnamon (LEC) rat. The magnetic resonance imaging (MRI) of LEC rats revealed tumors in the liver clearly and semi-quantitatively due to a labeling of macrophages in liver. The fluorescent imaging (FI) showed abnormal fluorescent patterns of the liver at the mesoscopic level that was between macroscopic and microscopic level. We performed correlation analysis between optical imaging including FI and MRI. We found that the labeled macrophages located specific area in the tumor tissue and influenced the tumor size on MRI. In addition histological observation showed the labeled macrophages related specific tissue in the pathological region. We demonstrated a new approach to evaluate tumor tissue at the macroscopic and microscopic level as well as mesoscopic level using multimodal imaging. |
|||
キーワード | 推奨 | ||||
発行所 | 推奨 | ||||
誌名 | 必須 |
Scientific Reports([Nature Publishing Group])
(eISSN: 2045-2322)
|
|||
巻 | 必須 | 7 | |||
号 | 必須 | 1 | |||
頁 | 必須 | 3953 3953 | |||
都市 | 任意 | ||||
年月日 | 必須 | 2017年 6月 21日 | |||
URL | 任意 | ||||
DOI | 任意 | 10.1038/s41598-017-04043-7 (→Scopusで検索) | |||
PMID | 任意 | 28638087 (→Scopusで検索) | |||
CRID | 任意 | ||||
WOS | 任意 | ||||
Scopus | 任意 | 2-s2.0-85021237425 | |||
評価値 | 任意 | ||||
被引用数 | 任意 | ||||
指導教員 | 推奨 | ||||
備考 | 任意 |
|