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著作: 廣野 明/[楠瀬 賢也]/Kageyama Norihito/Sumitomo Masayuki/Abe Masahiro/Fujinaga Hiroyuki/[佐田 政隆]/Development and validation of optimal cut-off value in inter-arm systolic blood pressure difference for prediction of cardiovascular events/[Journal of Cardiology]

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EID
341714
EOID
951561
Map
0
LastModified
2019年7月29日(月) 13:57:00
Operator
三木 ちひろ
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TRUE
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Owner
佐田 政隆
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種別 必須 学術論文(審査論文)
言語 必須 英語
招待 推奨
審査 推奨 Peer Review
カテゴリ 推奨
共著種別 推奨
学究種別 推奨
組織 推奨
著者 必須
  1. (英) Hirono Akira / (日) 廣野 明 / (読) ひろの あきら
    役割 任意
    貢献度 任意
    学籍番号 推奨 ****
  2. 楠瀬 賢也([徳島大学.病院.診療科.内科.循環器内科])
    役割 任意
    貢献度 任意
    学籍番号 推奨
  3. (英) Kageyama Norihito
    役割 任意
    貢献度 任意
    学籍番号 推奨
  4. (英) Sumitomo Masayuki
    役割 任意
    貢献度 任意
    学籍番号 推奨
  5. (英) Abe Masahiro
    役割 任意
    貢献度 任意
    学籍番号 推奨
  6. (英) Fujinaga Hiroyuki
    役割 任意
    貢献度 任意
    学籍番号 推奨
  7. 佐田 政隆([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.循環器内科学])
    役割 任意
    貢献度 任意
    学籍番号 推奨
題名 必須

(英) Development and validation of optimal cut-off value in inter-arm systolic blood pressure difference for prediction of cardiovascular events

副題 任意
要約 任意

(英) An inter-arm systolic blood pressure difference (IAD) is associated with cardiovascular disease. The aim of this study was to develop and validate the optimal cut-off value of IAD as a predictor of major adverse cardiac events in patients with arteriosclerosis risk factors. From 2009 to 2014, 1076 patients who had at least one cardiovascular risk factor were included in the analysis. We defined 700 randomly selected patients as a development cohort to confirm that IAD was the predictor of cardiovascular events and to determine optimal cut-off value of IAD. Next, we validated outcomes in the remaining 376 patients as a validation cohort. The blood pressure (BP) of both arms measurements were done simultaneously using the ankle-brachial blood pressure index (ABI) form of automatic device. The primary endpoint was the cardiovascular event and secondary endpoint was the all-cause mortality. During a median period of 2.8 years, 143 patients reached the primary endpoint in the development cohort. In the multivariate Cox proportional hazards analysis, IAD was the strong predictor of cardiovascular events (hazard ratio: 1.03, 95% confidence interval: 1.01-1.05, p=0.005). The receiver operating characteristic curve revealed that 5mmHg was the optimal cut-off point of IAD to predict cardiovascular events (p<0.001). In the validation cohort, the presence of a large IAD (IAD ≥5mmHg) was significantly associated with the primary endpoint (p=0.021). IAD is significantly associated with future cardiovascular events in patients with arteriosclerosis risk factors. The optimal cut-off value of IAD is 5mmHg.

キーワード 推奨
  1. (英) Aged
  2. (英) Aged, 80 and over
  3. (英) Arm
  4. 血圧(blood pressure)
  5. (英) Blood Pressure Determination
  6. (英) Cardiovascular Diseases
  7. (英) Female
  8. (英) Humans
  9. (英) Male
  10. (英) Middle Aged
  11. (英) Risk Factors
  12. (英) Systole
発行所 推奨 (日) .
誌名 必須 Journal of Cardiology([日本心臓病学会])
(pISSN: 0914-5087, eISSN: 1876-4738)
ISSN 任意 0914-5087
ISSN: 0914-5087 (pISSN: 0914-5087, eISSN: 1876-4738)
Title: Journal of cardiology
Title(ISO): J Cardiol
Publisher: Nippon-Shinzobyo-Gakkai/Japanese College of Cardiology
 (NLM Catalog  (医中誌Web  (Scopus  (CrossRef (Scopus information is found. [need login])
必須 71
必須 20
必須 24 30
都市 任意
年月日 必須 2018年 1月 初日
URL 任意
DOI 任意 10.1016/j.jjcc.2017.06.010    (→Scopusで検索)
PMID 任意 28830651    (→Scopusで検索)
CRID 任意
WOS 任意
Scopus 任意 2-s2.0-85027682866
評価値 任意
被引用数 任意
指導教員 推奨
備考 任意
  1. (英) Article.ELocationID: S0914-5087(17)30197-1

  2. (英) Article.ELocationID: 10.1016/j.jjcc.2017.06.010

  3. (英) Article.PublicationTypeList.PublicationType: Journal Article

  4. (英) KeywordList.Keyword: Cardiovascular risk

  5. (英) KeywordList.Keyword: Inter-arm systolic blood pressure difference

  6. (英) KeywordList.Keyword: Optimal cut-off value