徳島大学 教育・研究者情報データベース(EDB)

Education and Research Database (EDB), Tokushima University

徳島大学ウェブサイトへのリンク

著作: [楠瀬 賢也]/Obuchowski A. Nancy/Gillinov Marc/Popovic B. Zoran/Flamm D. Scott/Griffin P. Brian/Kwon H. Deborah/Predictors of Mortality in Patients With Severe Ischemic Cardiomyopathy Undergoing Surgical Mitral Valve Intervention./[Journal of the American Heart Association]

ヘルプを読む

「著作」(著作(著書,論文,レター,国際会議など))は,研究業績にかかる著作(著書,論文,レター,国際会議など)を登録するテーブルです. (この情報が属するテーブルの詳細な定義を見る)

  • 項目名の部分にマウスカーソルを置いて少し待つと,項目の簡単な説明がツールチップ表示されます.

この情報をEDB閲覧画面で開く

EID
340930
EOID
939694
Map
0
LastModified
2019年3月2日(土) 20:41:48
Operator
[ADMIN]
Avail
TRUE
Censor
0
Owner
楠瀬 賢也
Read
継承
Write
継承
Delete
継承
種別 必須 学術論文(審査論文)
言語 必須 英語
招待 推奨
審査 推奨
カテゴリ 推奨 研究
共著種別 推奨
学究種別 推奨
組織 推奨
著者 必須
  1. 楠瀬 賢也([徳島大学.病院.診療科.内科.循環器内科])
    役割 任意
    貢献度 任意
    学籍番号 推奨
  2. (英) Obuchowski A. Nancy
    役割 任意
    貢献度 任意
    学籍番号 推奨
  3. (英) Gillinov Marc
    役割 任意
    貢献度 任意
    学籍番号 推奨
  4. (英) Popovic B. Zoran
    役割 任意
    貢献度 任意
    学籍番号 推奨
  5. (英) Flamm D. Scott
    役割 任意
    貢献度 任意
    学籍番号 推奨
  6. (英) Griffin P. Brian
    役割 任意
    貢献度 任意
    学籍番号 推奨
  7. (英) Kwon H. Deborah
    役割 任意
    貢献度 任意
    学籍番号 推奨
題名 必須

(英) Predictors of Mortality in Patients With Severe Ischemic Cardiomyopathy Undergoing Surgical Mitral Valve Intervention.

副題 任意
要約 任意

(英) Ischemic mitral regurgitation is associated with substantial risk of death. Although surgical mitral valve intervention (MVi) may improve symptoms, it has not been shown to improve survival. The aim of this study was to identify predictors of mortality in patients with ischemic mitral regurgitation and MVi. We evaluated 117 consecutive patients (age, 65±10 years) with advanced ischemic cardiomyopathy who underwent cardiac magnetic resonance and subsequent MVi between January 1, 2002 and January 1, 2012. Cardiac magnetic resonance was used to assess left ventricular remodeling and myocardial scarring. The effective regurgitant orifice area was calculated from the proximal isovelocity surface area by echocardiography. There were 43 deaths (37%) during follow-up (median, 62 months). On multivariable analysis, age ≥70 years (=0.013), diabetes mellitus (=0.001), dyslipidemia (=0.012), papillary muscle scar (=0.010), incomplete revascularization (=0.001), and total scar %×effective regurgitant orifice area ≥0.20 cm (=0.005) were each independently associated with all-cause mortality. Although patients with effective regurgitant orifice area <0.2 cm at baseline demonstrated an increased hazard ratio of 3.3 for every 10% increase in scar, the hazard ratio increased to 9 for every 10% increase in scar in those with baseline effective regurgitant orifice area ≥0.20 cm. Mortality also was significantly higher in patients with incomplete revascularization compared with those with vascularized viable myocardium (61% versus 28%; <0.001). Increased total scar burden and the presence of incomplete revascularization are powerful predictors of mortality in patients with advanced ischemic cardiomyopathy undergoing MVi. Viability assessment with cardiac magnetic resonance imaging can identify which patients with ischemic mitral regurgitation are at highest risk for mortality after surgical MVi.

キーワード 推奨
  1. (英) Aged
  2. (英) Cardiomyopathies
  3. (英) Cause of Death
  4. (英) Echocardiography
  5. (英) Female
  6. (英) Follow-Up Studies
  7. (英) Heart Valve Prosthesis Implantation
  8. (英) Humans
  9. (英) Magnetic Resonance Imaging, Cine
  10. (英) Male
  11. (英) Middle Aged
  12. (英) Mitral Valve
  13. (英) Mitral Valve Insufficiency
  14. 心筋虚血(myocardial ischemia)
  15. (英) Retrospective Studies
  16. (英) Risk Assessment
  17. (英) Risk Factors
  18. (英) Severity of Illness Index
  19. (英) Survival Rate
  20. (英) United States
発行所 推奨
誌名 必須 Journal of the American Heart Association([American Heart Association]/American Stroke Association)
(eISSN: 2047-9980)
ISSN 任意 2047-9980
ISSN: 2047-9980 (eISSN: 2047-9980)
Title: Journal of the American Heart Association
Title(ISO): J Am Heart Assoc
Publisher: American Heart Association
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
必須 6
必須 11
必須 e007163 e007163
都市 任意
年月日 必須 2017年 11月 17日
URL 任意
DOI 任意 10.1161/JAHA.117.007163    (→Scopusで検索)
PMID 任意 29150492    (→Scopusで検索)
NAID 任意
WOS 任意
Scopus 任意 2-s2.0-85034775846
機関リポジトリ 113032
評価値 任意
被引用数 任意
指導教員 推奨
備考 任意
  1. (英) Article.ELocationID: e007163

  2. (英) Article.ELocationID: 10.1161/JAHA.117.007163

  3. (英) Article.PublicationTypeList.PublicationType: Journal Article

  4. (英) Article.PublicationTypeList.PublicationType: Observational Study

  5. (英) KeywordList.Keyword: ischemic cardiomyopathy

  6. (英) KeywordList.Keyword: magnetic resonance imaging

  7. (英) KeywordList.Keyword: mitral valve regurgitation

  8. (英) KeywordList.Keyword: myocardial delayed enhancement

  9. (英) KeywordList.Keyword: revascularization