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著作: [早渕 康信]/Ono Akemi/Homma Yukako/[香美 祥二]/Assessment of pulmonary arterial compliance evaluated using harmonic oscillator kinematics./[Pulmonary Circulation]

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336887
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2018年3月15日(木) 19:42:58
Operator
大家 隆弘
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早渕 康信
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種別 必須 学術論文(審査論文)
言語 必須 英語
招待 推奨
審査 推奨 Peer Review
カテゴリ 推奨 研究
共著種別 推奨
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著者 必須
  1. 早渕 康信([徳島大学.病院.中央診療施設等.地域小児科診療部])
    役割 任意
    貢献度 任意
    学籍番号 推奨
  2. (英) Ono Akemi
    役割 任意 共著
    貢献度 任意
    学籍番号 推奨
  3. (英) Homma Yukako
    役割 任意 共著
    貢献度 任意
    学籍番号 推奨
  4. 香美 祥二([徳島大学])
    役割 任意
    貢献度 任意
    学籍番号 推奨
題名 必須

(英) Assessment of pulmonary arterial compliance evaluated using harmonic oscillator kinematics.

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(英) We hypothesized that K, a harmonic oscillator kinematics-derived spring constant parameter of the pulmonary artery pressure (PAP) profile, reflects PA compliance in pediatric patients. In this prospective study of 33 children (age range = 0.5-20 years) with various cardiac diseases, we assessed the novel parameter designated as Kcalculated using the pressure phase plane and the equation K = (dP/dt_max)/([Pmax - Pmin])/2), where dP/dt_max is the peak derivative of PAP, and Pmax - Pmin is the difference between the minimum and maximum PAP. PA compliance was also calculated using two conventional methods: systolic PA compliance (sPAC) was expressed as the stroke volume/Pmax - Pmin; and diastolic PA compliance (dPAC) was determined according to a two-element Windkessel model of PA diastolic pressure decay. In addition, data were recorded during abdominal compression to determine the influence of preload on K. A significant correlation was observed between Kand sPAC (r = 0.52, P = 0.0018), but not dPAC. Significant correlations were also seen with the time constant (τ) of diastolic PAP (r = -0.51, P = 0.0026) and the pulmonary vascular resistance index (r = -0.39, P = 0.0242). No significant difference in Kwas seen between before and after abdominal compression. Khad a higher intraclass correlation coefficient than other compliance and resistance parameters for both intra-observer and inter-observer variability (0.998 and 0.997, respectively). These results suggest that Kcan provide insight into the underlying mechanisms and facilitate the quantification of PA compliance.

キーワード 推奨
発行所 推奨 (英) SAGE Publishing
誌名 必須 Pulmonary Circulation(Pulmonary Vascular Research Institute (Canterbury England))
(pISSN: 2045-8932, eISSN: 2045-8940)
ISSN 任意 2045-8932
ISSN: 2045-8932 (pISSN: 2045-8932, eISSN: 2045-8940)
Title: Pulmonary circulation
Title(ISO): Pulm Circ
Publisher: SAGE Publications
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
必須 7
必須 3
必須 666 673
都市 任意
年月日 必須 2017年 7月 1日
URL 任意
DOI 任意 10.1177/2045893217714781    (→Scopusで検索)
PMID 任意 28621582    (→Scopusで検索)
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  1. (英) Article.ELocationID: 10.1177/2045893217714781

  2. (英) Article.PublicationTypeList.PublicationType: Journal Article

  3. (英) KeywordList.Keyword: children

  4. (英) KeywordList.Keyword: harmonic oscillator

  5. (英) KeywordList.Keyword: pressure phase plane