著作: [藤原 亜希子]/[三田村 佳典]/Inomoto Naoki/Sano Hiroki/Akaiwa Kei/[仙波 賢太郎]/Optical coherence tomographic parameters predictive of visual outcome after anti-vascular endothelial growth factor therapy for retinal vein occlusion/[Clinical Ophthalmology]
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種別 | 必須 | 学術論文(審査論文) | |||
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言語 | 必須 | 英語 | |||
招待 | 推奨 | ||||
審査 | 推奨 | ||||
カテゴリ | 推奨 | ||||
共著種別 | 推奨 | ||||
学究種別 | 推奨 | ||||
組織 | 推奨 | ||||
著者 | 必須 | ||||
題名 | 必須 |
(英) Optical coherence tomographic parameters predictive of visual outcome after anti-vascular endothelial growth factor therapy for retinal vein occlusion |
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副題 | 任意 | ||||
要約 | 任意 |
(英) To determine the optical coherence tomography (OCT) parameters that are predictive of visual outcome after anti-VEGF therapy for a retinal vein occlusion (RVO). Fifty-seven eyes with macular edema (ME) secondary to a central or branch RVO treated with bevacizumab or ranibizumab were studied. Spectral-domain OCT and microperimetry were performed before, 1, 3, and 6 months after the treatment and at the final visit. Central retinal thickness (CRT), macular volume (MV), integrity of the external limiting membrane (ELM), ellipsoid zone (EZ), and foveal bulge (FB), and photoreceptor outer segment (PROS) length were determined. The mean follow-up period was 17.8±11.5 months. In 46 of the 57 eyes, a resolution of the ME was achieved. The pretreatment CRT and MV, presence of intact ELM, EZ, and FB, and PROS length at the time of ME resolution were significantly correlated with the best-corrected visual acuity and retinal sensitivity at the final visit (P<0.050). Multiple regression analyses showed that the pretreatment MV had the highest correlation with the posttreatment best-corrected visual acuity and retinal sensitivity (P<0.050). The CRT, MV, ELM, EZ, FB, and PROS length are predictive factors for the visual outcome after anti-VEGF therapy for RVO. |
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キーワード | 推奨 | ||||
発行所 | 推奨 | ||||
誌名 | 必須 |
Clinical Ophthalmology(The Society of Clinical Ophthalmology)
(pISSN: 1177-5467, eISSN: 1177-5483)
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巻 | 必須 | 10 | |||
号 | 必須 | --- | |||
頁 | 必須 | 1305 1313 | |||
都市 | 任意 | ||||
年月日 | 必須 | 2016年 7月 18日 | |||
URL | 任意 | ||||
DOI | 任意 | 10.2147/OPTH.S110793 (→Scopusで検索) | |||
PMID | 任意 | 27486302 (→Scopusで検索) | |||
CRID | 任意 | ||||
WOS | 任意 | ||||
Scopus | 任意 | 2-s2.0-84982683416 | |||
評価値 | 任意 | ||||
被引用数 | 任意 | ||||
指導教員 | 推奨 | ||||
備考 | 任意 |
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