327195: Tokushige Akihiro/Ueda Shinichiro/Tomiyama Hirofumi/Ohishi Mituru/Kohro Takahide/Higashi Yukihito/Takase Bonpei/Suzuki Toru/Ishizu Tomoko/Yamazaki Tsutomu/Furumoto Tomoo/Kario Kazuomi/Inoue Teruo/Koba Shinji/Takemoto Yasuhiko/Hano Takuzo/[佐田政隆]/Ishibashi Yutaka/Node Koichi/Maemura Koji/Ohya Yusuke/Furukawa Taiji/Ito Hiroshi/Yamashina Akira/Association Between Waist-to-Height Ratio and Endothelial Dysfunction in Patients With Morbidity A Report From the FMD-J Study/[Circulation Journal]

著作: Tokushige Akihiro/Ueda Shinichiro/Tomiyama Hirofumi/Ohishi Mituru/Kohro Takahide/Higashi Yukihito/Takase Bonpei/Suzuki Toru/Ishizu Tomoko/Yamazaki Tsutomu/Furumoto Tomoo/Kario Kazuomi/Inoue Teruo/Koba Shinji/Takemoto Yasuhiko/Hano Takuzo/[佐田政隆]/Ishibashi Yutaka/Node Koichi/Maemura Koji/Ohya Yusuke/Furukawa Taiji/Ito Hiroshi/Yamashina Akira/Association Between Waist-to-Height Ratio and Endothelial Dysfunction in Patients With Morbidity A Report From the FMD-J Study/[Circulation Journal]

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EID: 327195
EOID: 937593
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LastModified: 2019年1月9日(水) 15:07:15
Operator: 三木ちひろ
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Censor: 承認済
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種別

必須

学術論文(審査論文)

言語

必須

英語

招待

推奨

審査

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Peer Review

カテゴリ

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研究

共著種別

推奨

学究種別

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組織

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著者

必須

(英) Tokushige Akihiro

役割任意

貢献度任意

学籍番号推奨
(英) Ueda Shinichiro

役割任意

貢献度任意

学籍番号推奨
(英) Tomiyama Hirofumi

役割任意

貢献度任意

学籍番号推奨
(英) Ohishi Mituru

役割任意

貢献度任意

学籍番号推奨
(英) Kohro Takahide

役割任意

貢献度任意

学籍番号推奨
(英) Higashi Yukihito

役割任意

貢献度任意

学籍番号推奨
(英) Takase Bonpei

役割任意

貢献度任意

学籍番号推奨
(英) Suzuki Toru

役割任意

貢献度任意

学籍番号推奨
(英) Ishizu Tomoko

役割任意

貢献度任意

学籍番号推奨
(英) Yamazaki Tsutomu

役割任意

貢献度任意

学籍番号推奨
(英) Furumoto Tomoo

役割任意

貢献度任意

学籍番号推奨
(英) Kario Kazuomi

役割任意

貢献度任意

学籍番号推奨
(英) Inoue Teruo

役割任意

貢献度任意

学籍番号推奨
(英) Koba Shinji

役割任意

貢献度任意

学籍番号推奨
(英) Takemoto Yasuhiko

役割任意

貢献度任意

学籍番号推奨
(英) Hano Takuzo

役割任意

貢献度任意

学籍番号推奨
佐田政隆([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.循環器内科学])

役割任意

貢献度任意

学籍番号推奨
(英) Ishibashi Yutaka

役割任意

貢献度任意

学籍番号推奨
(英) Node Koichi

役割任意

貢献度任意

学籍番号推奨
(英) Maemura Koji

役割任意

貢献度任意

学籍番号推奨
(英) Ohya Yusuke

役割任意

貢献度任意

学籍番号推奨
(英) Furukawa Taiji

役割任意

貢献度任意

学籍番号推奨
(英) Ito Hiroshi

役割任意

貢献度任意

学籍番号推奨
(英) Yamashina Akira

役割任意

貢献度任意

学籍番号推奨

題名

必須

(英) Association Between Waist-to-Height Ratio and Endothelial Dysfunction in Patients With Morbidity A Report From the FMD-J Study

副題

任意

要約

任意

(英) Waist circumference (WC), waist-to-height ratio (WHtR) and body mass index (BMI) are known as easy anthropometric markers of abnormal obesity and screening tools for predicting cardiovascular outcomes, but which indices are best is unclear. We therefore investigated the superiority and association between each index and low flow-mediated dilatation (FMD) as a surrogate marker for cardiovascular outcomes in patients with morbidity in a large Japanese prospective cohort.Methods and Results:A total of 1,645 Japanese patients who had coronary artery disease and hypertension or diabetes mellitus were enrolled, and 1,087 of them were analyzed. The high-WHtR group (≥0.5) showed greater morbidity and increased inflammation in association with atherosclerosis compared with the low-WHtR group. High WHtR and advanced age were identified as predictors of low FMD (odds ratio (OR) 1.39, 95% confidence interval (CI) 1.02-1.88, P=0.037 and OR 1.55, 95% CI 1.19-2.01, P=0.001, respectively). However, WC was not associated with that risk in either sex (male: OR 1.37, 95% CI 0.97-1.93, P=0.076; female: OR 1.08, 95% CI 0.68-1.73, P=0.74), and no association was evident between high BMI and low FMD (OR 0.92, 95% CI 0.71-1.19, P=0.54). WHtR offers a superior predictor of decreased FMD than other anthropometric indices, and progression of arteriosclerosis might be detected more sensitively. Further study is needed to investigate the relationship between cardiovascular mortality and WHtR.

キーワード

推奨

(英) Aged
(英) Asian Continental Ancestry Group
動脈硬化(atherosclerosis)
(英) Dilatation
(英) Disease Progression
(英) Endothelium
(英) Female
(英) Humans
(英) Male
(英) Middle Aged
(英) Morbidity
(英) Prospective Studies
(英) Waist-Height Ratio

発行所

推奨

社団法人日本循環器学会

誌名

必須

Circulation Journal([社団法人日本循環器学会])

(pISSN: 1346-9843, eISSN: 1347-4820)

ISSN	任意	1347-4820 ISSN: 1346-9843 (pISSN: 1346-9843, eISSN: 1347-4820) Title: Circulation journal : official journal of the Japanese Circulation Society Title(ISO): Circ J Supplier: 社団法人日本循環器学会 Publisher: Japanese Circulation Society (NLM Catalog) (Webcat Plus) (医中誌Web) (J-STAGE) (Scopus) (CrossRef) (Scopus information is found. [need login])

巻

必須

号

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頁

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1911 1918

都市

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年月日

必須

2017年 7月 7日

URL

任意

DOI

任意

10.1253/circj.CJ-17-0211 (→Scopusで検索)

PMID

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28690284 (→Scopusで検索)

CRID

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WOS

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Scopus

任意

2-s2.0-85035216086

評価値

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被引用数

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指導教員

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備考

任意

(英) Article.ELocationID: 10.1253/circj.CJ-17-0211
(英) Article.PublicationTypeList.PublicationType: Journal Article
(英) KeywordList.Keyword: Body mass index
(英) KeywordList.Keyword: Endothelial dysfunction
(英) KeywordList.Keyword: Flow-mediated vasodilatation
(英) KeywordList.Keyword: Waist circumference
(英) KeywordList.Keyword: Waist-to-height ratio

徳島大学教育・研究者情報データベース(EDB)

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