326405: Nanri Hinako/Nishida Yuichiro/Nakamura Kazuyo/Tanaka Keitaro/Naito Mariko/Yin Guang/Hamajima Nobuyuki/Takashima Naoyuki/Suzuki Sadao/Nindita Yora/Kohno Michiko/[上村浩一]/Koyama Teruhide/Hosono Satoyo/Mikami Haruo/Kubo Michiaki/Tanaka Hideo/Associations between Dietary Patterns, ADR 2 Gln27Glu and ADR 3 Trp64Arg with Regard to Serum Triglyceride Levels: J-MICC Study./[Nutrients]

著作: Nanri Hinako/Nishida Yuichiro/Nakamura Kazuyo/Tanaka Keitaro/Naito Mariko/Yin Guang/Hamajima Nobuyuki/Takashima Naoyuki/Suzuki Sadao/Nindita Yora/Kohno Michiko/[上村浩一]/Koyama Teruhide/Hosono Satoyo/Mikami Haruo/Kubo Michiaki/Tanaka Hideo/Associations between Dietary Patterns, ADR 2 Gln27Glu and ADR 3 Trp64Arg with Regard to Serum Triglyceride Levels: J-MICC Study./[Nutrients]

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種別

必須

学術論文(審査論文)

言語

必須

英語

招待

推奨

審査

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カテゴリ

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共著種別

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学究種別

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組織

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著者

必須

(英) Nanri Hinako

役割任意

貢献度任意

学籍番号推奨
(英) Nishida Yuichiro

役割任意

貢献度任意

学籍番号推奨
(英) Nakamura Kazuyo

役割任意

貢献度任意

学籍番号推奨
(英) Tanaka Keitaro

役割任意

貢献度任意

学籍番号推奨
(英) Naito Mariko

役割任意

貢献度任意

学籍番号推奨
(英) Yin Guang

役割任意

貢献度任意

学籍番号推奨
(英) Hamajima Nobuyuki

役割任意

貢献度任意

学籍番号推奨
(英) Takashima Naoyuki

役割任意

貢献度任意

学籍番号推奨
(英) Suzuki Sadao

役割任意

貢献度任意

学籍番号推奨
(英) Nindita Yora

役割任意

貢献度任意

学籍番号推奨
(英) Kohno Michiko

役割任意

貢献度任意

学籍番号推奨
上村浩一

役割任意

貢献度任意

学籍番号推奨
(英) Koyama Teruhide

役割任意

貢献度任意

学籍番号推奨
(英) Hosono Satoyo

役割任意

貢献度任意

学籍番号推奨
(英) Mikami Haruo

役割任意

貢献度任意

学籍番号推奨
(英) Kubo Michiaki

役割任意

貢献度任意

学籍番号推奨
(英) Tanaka Hideo

役割任意

貢献度任意

学籍番号推奨

題名

必須

(英) Associations between Dietary Patterns, ADR 2 Gln27Glu and ADR 3 Trp64Arg with Regard to Serum Triglyceride Levels: J-MICC Study.

副題

任意

要約

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(英) Interactions between dietary patterns and 2 -adrenergic receptor (ADR ) gene polymorphisms (ADR 2 Gln27Glu and ADR 3 Trp64Arg) were examined with regard to the effects on serum triglyceride levels. The cross-sectional study comprised 1720 men and women (aged 35-69 years) enrolled in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study. Genotyping was conducted using a multiplex polymerase chain reaction-based invader assay. We used 46 items from a validated short food frequency questionnaire and examined major dietary patterns by factor analysis. We identified four dietary patterns: healthy, Western, seafood and bread patterns. There was no significant association between any dietary pattern and serum triglyceride levels. After a separate genotype-based analysis, significant interactions between ADR 3 Trp64Arg genotype and the bread pattern (p for interaction = 0.01) were associated with serum triglyceride levels; specifically, after adjusting for confounding factors, Arg allele carriers with the bread pattern had lower serum triglycerides (p for trend = 0.01). However, the Trp/Trp homozygous subjects with the bread pattern showed no association with serum triglycerides (p for trend = 0.55). Interactions between other dietary patterns and ADR polymorphisms were not significant for serum triglyceride levels. Our findings suggest that ADR 3 polymorphism modifies the effects of the bread pattern on triglyceride levels.

キーワード

推奨

(英) Adult
(英) Aged
(英) Alleles
(英) Cohort Studies
(英) Cross-Sectional Studies
(英) Diet
(英) Female
(英) Genotyping Techniques
(英) Heterozygote
(英) Homozygote
(英) Humans
(英) Japan
(英) Linear Models
(英) Male
(英) Middle Aged
(英) Nutrition Assessment
(英) Polymorphism, Genetic
(英) Receptors, Adrenergic, beta-2
(英) Receptors, Adrenergic, beta-3
(英) Reproducibility of Results
(英) Surveys and Questionnaires
(英) Triglycerides

発行所

推奨

誌名

必須

Nutrients(Molecular Diversity Preservation International)

(eISSN: 2072-6643)

ISSN	任意	2072-6643 ISSN: 2072-6643 (eISSN: 2072-6643) Title: Nutrients Title(ISO): Nutrients Publisher: Multidisciplinary Digital Publishing Institute (MDPI) (NLM Catalog) (Scopus) (CrossRef) (Scopus information is found. [need login])

巻

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号

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頁

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都市

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年月日

必須

2016年 9月 6日

URL

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DOI

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10.3390/nu8090545 (→Scopusで検索)

PMID

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27608039 (→Scopusで検索)

CRID

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Scopus

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researchmap

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評価値

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被引用数

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指導教員

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備考

任意

(英) Article.ELocationID: 10.3390/nu8090545
(英) Article.ELocationID: E545
(英) Article.PublicationTypeList.PublicationType: Journal Article
(英) KeywordList.Keyword: dietary pattern
(英) KeywordList.Keyword: factor analysis
(英) KeywordList.Keyword: polymorphism
(英) KeywordList.Keyword: triglyceride
(英) KeywordList.Keyword: -adrenergic receptor (ADR )
(英) CoiStatement: The authors declare no conflicts of interest.

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