徳島大学 教育・研究者情報データベース(EDB)

1. 大塚 秀樹([徳島大学.大学院医歯薬学研究部.保健学域.保健科学部門.放射線科学系.画像医学・核医学]/[徳島大学.医学部.保健学科.放射線技術科学専攻.診療放射線技術学講座])

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2. (英) Terazawa Kaori

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3. 森田 奈緒美

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4. (英) Otomi Yoichi

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5. 髙尾 正一郎([徳島大学.大学院医歯薬学研究部.保健学域.保健科学部門.放射線科学系.医用画像解析学]/[徳島大学.医学部.保健学科.放射線技術科学専攻.診療放射線技術学講座])

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6. 岩本 誠司

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7. 尾﨑 享祐

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8. 原田 雅史([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.放射線医学])

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9. 西谷 弘

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(英) Thallium-201 chloride scintigraphy in soft tissue tumors.

(英) We report the findings of Thallium-201 chloride ((201)TlCl) scintigraphy and consider how to use this technique to evaluate the character of soft tissue lesions. We enrolled 91 consecutive patients (45 males and 46 females, age range 8-91-years-old). Nineteen patients were malignant and 72 were benign. Patients were scanned 15 minutes (early phase) and 3 hours (delayed phase) after (201)TlCl injection. More intense uptake in the lesion compared to the normal side was considered as 'high', the same degree of uptake was considered 'iso', and decreased uptake was 'low'. The retention index (RI) was calculated in 9 patients in the malignant group and in 16 patients in the benign group. In malignant tumors, 15 of 19 patients showed high uptake in both the early and delayed phases. One malignant fibrous histiocytoma patient was high only in the delayed phase and 1 liposarcoma patient was high only in the early phase. Two liposarcoma patients showed an iso uptake in both phases. One of these patients was pathologically diagnosed as a myxoid type. In benign lesions, no lipoma showed increased uptake. All neurogenic tumors except for 2 demonstrated high uptake. All 3 ganglions of the lower extremities showed iso uptake. Most inflammatory diseases showed increased uptake. Clinically-considered benign patients consisted of tumorous lesions or inflammatory disease. Only 2 patients were considered 'low', and these were diagnosed as intramuscular hematoma and cyst. RI was variable in both malignant and benign lesions and no statistically significant difference was seen between malignant and benign lesions by t-test (p=0.72). A high (201)TlCl uptake lesion is more frequently seen in malignant tumors, but regardless of whether the tumor is benign or malignant, according to the histopathological variety, the (201)TlCl uptake pattern can not be the only indicator to differentiate malignant from benign tumors. We ultimately need to evaluate the nature of tumors by a combination of several imaging techniques.

1. (英) Adolescent
2. (英) Adult
3. (英) Aged
4. (英) Aged, 80 and over
5. 子ども(children)
6. (英) Diagnosis, Differential
7. (英) Female
8. (英) Histiocytoma, Malignant Fibrous
9. (英) Humans
10. (英) Liposarcoma
11. 磁気共鳴映像法(magnetic resonance imaging)
12. (英) Male
13. (英) Middle Aged
14. (英) Radiopharmaceuticals
15. (英) Soft Tissue Neoplasms
16. (英) Thallium
17. (英) Thallium Radioisotopes
18. (英) Young Adult

1. (英) Article.PublicationTypeList.PublicationType: Evaluation Studies

2. (英) Article.PublicationTypeList.PublicationType: Journal Article