著作: [山本 伸昭]/[寺澤 由佳]/[里見 淳一郎]/酒井 和香/[原田 雅史]/[和泉 唯信]/[永廣 信治]/[梶 龍兒]/Predictors of neurologic deterioration in patients with small-vessel occlusion and infarcts in the territory of perforating arteries/[Journal of Stroke & Cerebrovascular Diseases]
(英) Predictors of neurologic deterioration in patients with small-vessel occlusion and infarcts in the territory of perforating arteries
(英) It is difficult to predict neurologic deterioration in patients with small-vessel occlusion (SVO), that is, small infarcts in the territory of cerebral perforating arteries. We reviewed 110 patients with SVO who were admitted to our hospital. We divided them into groups with (n = 32, group 1) and without deterioration (n = 78, group 2) and evaluated their medical records, risk factors, magnetic resonance imaging findings, grade of periventricular hyperintensity (PVH), maximum diameter of the infarct area, and the number of slices showing infarcts on diffusion-weighted images (DWI). Our study population consisted of 110 patients (71 males and 39 females; mean age 69.2 years): 32 (29%) did and 78 (71%) did not suffer deterioration. By univariate analysis, the age, current smoking, history of stroke, maximum diameter of the infarcted area, number of DWI slices with infarcts, frequency of PVH, and PVH grade based on Fazekas classification differed significantly between the 2 groups. By multivariate analysis, conventional risk factors other than PVH and history of stroke were not associated with neurologic deterioration (PVH grade ≥ 2 versus PVH grade ≤ 1, odds ratio 6.72, P = .006; with stroke versus without stroke, odds ratio .21, P = .049). We also found that higher the PVH grade, the worse the National Institutes of Health Stroke Scale score at the time of discharge. PVH and without history of stroke are independently associated with neurologic deterioration in patients with SVO.
Journal of Stroke & Cerebrovascular Diseases(National Stroke Association/日本脳卒中学会)
|年月日||必須||2014年 9月 初日|