徳島大学 教育・研究者情報データベース(EDB)

Education and Research Database (EDB), Tokushima University

徳島大学ウェブサイトへのリンク

著作: [楊河 宏章]/木宿 昌俊/[赤池 雅史]/[東 博之]/[苛原 稔]/View of physicians on and barriers to patient enrollment in a multicenter clinical trial: experience in a Japanese rural area/[International Archives of Medicine]

ヘルプを読む

「著作」(著作(著書,論文,レター,国際会議など))は,研究業績にかかる著作(著書,論文,レター,国際会議など)を登録するテーブルです. (この情報が属するテーブルの詳細な定義を見る)

  • 項目名の部分にマウスカーソルを置いて少し待つと,項目の簡単な説明がツールチップ表示されます.

この情報をEDB閲覧画面で開く

EID
236808
EOID
657355
Map
0
LastModified
2012年9月3日(月) 16:56:09
Operator
大家 隆弘
Avail
TRUE
Censor
0
Owner
赤池 雅史
Read
継承
Write
継承
Delete
継承
種別 必須 学術論文(審査論文)
言語 必須 英語
招待 推奨
審査 推奨 Peer Review
カテゴリ 推奨 研究
共著種別 推奨
学究種別 推奨
組織 推奨
著者 必須
  1. 楊河 宏章([徳島大学.病院.中央診療施設等.総合臨床研究センター])
    役割 任意
    貢献度 任意
    学籍番号 推奨
  2. (英) Kishuku Masatoshi / (日) 木宿 昌俊
    役割 任意
    貢献度 任意
    学籍番号 推奨
  3. 赤池 雅史([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.社会医学系.医療教育学])
    役割 任意
    貢献度 任意
    学籍番号 推奨
  4. 東 博之
    役割 任意
    貢献度 任意
    学籍番号 推奨
  5. 苛原 稔([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.産科婦人科学])
    役割 任意
    貢献度 任意
    学籍番号 推奨
題名 必須

(英) View of physicians on and barriers to patient enrollment in a multicenter clinical trial: experience in a Japanese rural area

副題 任意
要約 任意

(英) Clinical trials in the general practice setting are important for providing evidence on the effectiveness and safety of different agents under various conditions. In conducting these trials, the participation of physicians and patient recruitment are important issues. Various investigations in the literature have reported views and attitudes of physicians on various types of clinical trials. Nevertheless, there is still little information concerning physicians participating in a clinical trial and among them, those who could not recruit any patients (unsuccessful physician recruiters). In 2003, we collaborated in a large-scale multicenter study of Japanese hypertensive patients (COPE Trial). In Tokushima University Hospital and 18 other medical institutions, we investigated the views and attitudes of unsuccessful physician recruiters in comparison with successful physician recruiters, using a questionnaire. The questionnaire was provided by mail to 47 physicians and 27 (57%) responded. The response rate was 79% for successful physician recruiters compared to 43% (P = 0.014) for unsuccessful physician recruiters. More successful physician recruiters (73%) than unsuccessful physician recruiters (42%) stated they had participated and enrolled patients in previous multicenter clinical trials. A significantly higher number of successful physician recruiters than unsuccessful physician recruiters (42%; P = 0.040) considered the presence of a support system with clinical research coordinators (CRC) as the reason for participation (80%). A large number of unsuccessful physician recruiters experienced difficulty in obtaining informed consent (67%), whereas a significantly smaller number of successful physician recruiters experienced such difficulty (20%; P = 0.014). The difficulties experienced by unsuccessful physician recruiters in the trial were as follows: inability to find possible participants (100%), difficulty in obtaining informed consent (58%), cumbersome procedures (58%), difficulty in long-term follow up (33%), and insufficient tools for explanation and obtaining informed consent (8%). This survey showed that successful physician recruiters consider a support system with CRC of value, and that they are skillful in obtaining informed consent. These views and attitudes may have originated from past experience involving clinical trials. In this regard, we need to develop an infrastructure to enlighten physicians on this support system for the promotion of clinical trials.

キーワード 推奨
発行所 推奨
誌名 必須 International Archives of Medicine([BioMed Central Ltd.])
(eISSN: 1755-7682)
ISSN 任意 1755-7682
ISSN: 1755-7682 (eISSN: 1755-7682)
Title: International archives of medicine
Title(ISO): Int Arch Med
Publisher: BioMed Central
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
必須 3
必須 1
必須 7 7
都市 任意
年月日 必須 2010年 6月 4日
URL 任意
DOI 任意 10.1186/1755-7682-3-7    (→Scopusで検索)
PMID 任意 20525325    (→Scopusで検索)
NAID 任意
WOS 任意
Scopus 任意
評価値 任意
被引用数 任意
指導教員 推奨
備考 任意
  1. (英) Article.Affiliation: Clinical Trial Center for Developmental Therapeutics, Tokushima University Hospital, Tokushima, Japan. niseko@clin.med.tokushima-u.ac.jp.

  2. (英) Article.PublicationTypeList.PublicationType: Journal Article

  3. (英) OtherID: PMC2893519