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著作: Seike Junichi/[丹黒 章]/Yuasa Yasuhiro/Okitsu Hiroshi/[川上 行奎]/Sumitomo Masayuki/The effect of nutritional support on the immune function in the acute postoperative period after esophageal cancer surgery: total parenteral nutrition versus enteral nutrition./[The Journal of Medical Investigation : JMI]

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EID
229731
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877449
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丹黒 章
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種別 必須 学術論文(審査論文)
言語 必須 英語
招待 推奨
審査 推奨
カテゴリ 推奨
共著種別 推奨
学究種別 推奨
組織 推奨
著者 必須
  1. (英) Seike Junichi
    役割 任意
    貢献度 任意
    学籍番号 推奨
  2. 丹黒 章([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.胸部・内分泌・腫瘍外科学])
    役割 任意
    貢献度 任意
    学籍番号 推奨
  3. (英) Yuasa Yasuhiro
    役割 任意
    貢献度 任意
    学籍番号 推奨
  4. (英) Okitsu Hiroshi
    役割 任意
    貢献度 任意
    学籍番号 推奨
  5. 川上 行奎([徳島大学.病院.中央診療施設等.地域外科診療部])
    役割 任意
    貢献度 任意
    学籍番号 推奨
  6. (英) Sumitomo Masayuki
    役割 任意
    貢献度 任意
    学籍番号 推奨
題名 必須

(英) The effect of nutritional support on the immune function in the acute postoperative period after esophageal cancer surgery: total parenteral nutrition versus enteral nutrition.

副題 任意

(英) Enteral nutrition (EN) is now used more frequently than total parenteral nutrition (TPN) for nutritional support after resection for esophageal cancer. But consensus regarding which type of nutrition should be used does not exist. We studied the effect of TPN and EN on patients' nutritional status and immune function in the immediate postoperative period after esophageal cancer resection.

要約 任意

(英) Enteral nutrition (EN) is now used more frequently than total parenteral nutrition (TPN) for nutritional support after resection for esophageal cancer. But consensus regarding which type of nutrition should be used does not exist. We studied the effect of TPN and EN on patients' nutritional status and immune function in the immediate postoperative period after esophageal cancer resection. We enrolled 30 patients (27 men and 3 women) who underwent subtotal esophagectomy. The patients were randomly assigned to TPN or EN group. Either TPN or EN was begun on postoperative day 1. On postoperative days 1, 3, and 7, three endpoints were measured: albumin, C-reactive protein, and Th1/Th2 balance. All patients completed the study. Anastomotic leaks occurred in 6 patients in the TPN group and 7 patients in the EN group. Albumin, Th1/Th2 balance, and C-reactive protein did not differ between the groups. Th1/Th2 balance was not different regardless of the preoperative treatment or complications. No differences in immune function, nutritional state, or inflammatory response were seen between patients supported with TPN and those supported with EN. The results of our study suggest that perioperative nutritional support can be safely performed either with TPN or EN.

キーワード 推奨
  1. (英) Aged
  2. (英) C-Reactive Protein
  3. (英) Enteral Nutrition
  4. (英) Esophageal Neoplasms
  5. (英) Female
  6. (英) Humans
  7. (英) Male
  8. (英) Middle Aged
  9. (英) Parenteral Nutrition, Total
  10. (英) Postoperative Care
  11. (英) Postoperative Period
  12. (英) Serum Albumin
  13. (英) Th1 Cells
  14. (英) Th2 Cells
発行所 推奨
誌名 必須 The Journal of Medical Investigation : JMI([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)
ISSN 任意 1349-6867
ISSN: 1343-1420 (pISSN: 1343-1420, eISSN: 1349-6867)
Title: The journal of medical investigation : JMI
Title(ISO): J Med Invest
Supplier: 徳島大学
Publisher: Tokushima Daigaku Igakubu
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
必須 58
必須 1-2
必須 75 80
都市 任意
年月日 必須 2011年 2月 初日
URL 任意
DOI 任意 10.2152/jmi.58.75    (→Scopusで検索)
PMID 任意 21372490    (→Scopusで検索)
NAID 任意
WOS 任意
Scopus 任意
機関リポジトリ 75864
評価値 任意
被引用数 任意
指導教員 推奨
備考 任意
  1. (英) Article.Affiliation: Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan.

  2. (英) Article.PublicationTypeList.PublicationType: Journal Article